CAS Number25739-41-7
Synonyms4',5-dihydroxy-3',7-dimethoxyflavone; 5,4'-dihydroxy-7,3'-dimethoxyflavone; Flavoyadorigenin B; 5-Hydroxy-2-(4-hydroxy-3-methoxyphenyl)-7-methoxy-4H-chromen-4-one; chrysoeriol-7-methyl ether; 5,4'-dihydroxy-7,3'-dimethoxylflavone; luteolin 7,3'-dimethyl ether; Velutin; 7,3'-di-O-methylluteolin
Molecular FormulaC17H14O6
Molecular Weight314.29
Density1.4±0.1 g/cm3
Boiling Point567.5±50.0 °C at 760 mmHg
Appearanceyellow powder
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 25739-41-7 |
| Catalog No. | 2A-9066757 |
| Chinese Name | 毡毛美洲茶素 |
| Synonyms | 4',5-dihydroxy-3',7-dimethoxyflavone; 5,4'-dihydroxy-7,3'-dimethoxyflavone; Flavoyadorigenin B; 5-Hydroxy-2-(4-hydroxy-3-methoxyphenyl)-7-methoxy-4H-chromen-4-one; chrysoeriol-7-methyl ether; 5,4'-dihydroxy-7,3'-dimethoxylflavone; luteolin 7,3'-dimethyl ether; Velutin; 7,3'-di-O-methylluteolin |
| Molecular Formula | C17H14O6 |
| Molecular Weight | 314.29 |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 567.5±50.0 °C at 760 mmHg |
| Appearance | yellow powder |
| Storage Condition | 2-8℃, dry, sealed |
| Application | Velutin is an aglycone extracted from mistletoe and has the activity of inhibiting melanin biosynthesis. Velutin reduces osteoclast differentiation and downregulates HIF-1α through the NF-κB pathway. |
| HTC | 2914509090 |
| MDL Number | MFCD20260863 |
| SMILES | COc1cc(O)c2c(=O)cc(-c3ccc(O)c(OC)c3)oc2c1 |
| InChI | InChI=1S/C17H14O6/c1-21-10-6-12(19)17-13(20)8-14(23-16(17)7-10)9-3-4-11(18)15(5-9)22-2/h3-8,18-19H,1-2H3 |
| InChI Key | ROCUOVBWAWAQFD-UHFFFAOYSA-N |
| MSDS | msds/66757_1_25739_41_7.pdf |
| Use of | Velutin is an aglycone extracted from Korean Mistletoe, with inhibitory activity against melanin biosynthesis. Velutin reduces osteoclast differentiation and down-regulates HIF-1α through the NF-κB pathway[1][2]. Properties Name 5-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-7-methoxychromen-4-one Synonym More Synonyms Velutin Biological Activity Description Velutin is an aglycone extracted from Korean Mistletoe, with inhibitory activity against melanin biosynthesis. Velutin reduces osteoclast differentiation and down-regulates HIF-1α through the NF-κB pathway[1][2]. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology References [1]. Jung SH, et al. Velutin, an Aglycone Extracted from Korean Mistletoe, with Improved Inhibitory Activity against Melanin Biosynthesis. Molecules. 2019 Jul 12;24(14). Chemical & Physical Properties Molecular Formula C17H14O6 Exact Mass 314.079041 PSA 89.13000 Index of Refraction 1.646 InChIKey ROCUOVBWAWAQFD-UHFFFAOYSA-N Safety Information Hazard Codes Xi HS Code 2914509090 Synthetic Route 5,4'-dihydroxy-... CAS#:1449692-19-6 CAS#:25739-41-7 Literature: Ahmad, Ateeque; Kim, Seung-Hyun; Ali, Mohd; Park, Inmyoung; Kim, Jin-Seog; Kim, Eun-Hye; Lim, Ju-Jin; Kim, Seul-Ki; Chung, Ill-Min Journal of Agricultural and Food Chemistry, 2013 , vol. 61, # 34 p. 8039 - 8048 CAS#:1449692-20-9 CAS#:25739-41-7 Literature: Ahmad, Ateeque; Kim, Seung-Hyun; Ali, Mohd; Park, Inmyoung; Kim, Jin-Seog; Kim, Eun-Hye; Lim, Ju-Jin; Kim, Seul-Ki; Chung, Ill-Min Journal of Agricultural and Food Chemistry, 2013 , vol. 61, # 34 p. 8039 - 8048 5,4'-dihydroxy-... CAS#:1449692-19-6 D-(+)-Xylose CAS#:58-86-6 CAS#:25739-41-7 stearic acid CAS#:57-11-4 Literature: Ahmad, Ateeque; Kim, Seung-Hyun; Ali, Mohd; Park, Inmyoung; Kim, Jin-Seog; Kim, Eun-Hye; Lim, Ju-Jin; Kim, Seul-Ki; Chung, Ill-Min Journal of Agricultural and Food Chemistry, 2013 , vol. 61, # 34 p. 8039 - 8048 Precursor & DownStream Precursor 3 CAS#:41877-53-6 (-)-5-hydroxy-2... CAS#:491-70-3 CAS#:1239-68-5 4'-Hydroxy-5,7,... DownStream 1 CAS#:855-97-0 5,7,3',4'-Tetra... |
| Tax Rebate | 9.0% |
| Supervision | None MFN tariff: 5.5% Ordinary tariff: 30.0% |
| Transport Info | Product name: Summary HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0% |
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