CAS Number1486-70-0
Synonyms2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-methoxychromen-4-one; 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-3-methoxy-4H-chromen-4-one; 3-methoxy-5,7,3',4'-tetrahydroxy-flavone; 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-3-methoxy-4H-1-benzopyran-4-one; 3-O-Methylquercetin
Molecular FormulaC16H12O7
Molecular Weight316.26
Purity≥97 (HPLC)%
Density1.7±0.1 g/cm3
Boiling Point643.0±55.0 °C at 760 mmHg
Appearancepowder
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 1486-70-0 |
| Catalog No. | 2A-9066376 |
| Chinese Name | 3-O-甲基槲皮素 |
| Synonyms | 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-methoxychromen-4-one; 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-3-methoxy-4H-chromen-4-one; 3-methoxy-5,7,3',4'-tetrahydroxy-flavone; 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-3-methoxy-4H-1-benzopyran-4-one; 3-O-Methylquercetin |
| Molecular Formula | C16H12O7 |
| Molecular Weight | 316.26 |
| Purity | ≥97 (HPLC) |
| Density | 1.7±0.1 g/cm3 |
| Boiling Point | 643.0±55.0 °C at 760 mmHg |
| Appearance | powder |
| Storage Condition | 2-8℃, dry, sealed |
| Application | 3-O-Methylquercetin (3-MQ) is a major component from the plant Rhamnus nakaharai and inhibits total cAMP and cGMP-phosphodiesterase (PDE). The IC50 values of 3-O-Methylquercetin (3-MQ) against PDE1, |
| HTC | 2914509090 |
| PubChem ID | 329769845 |
| MDL Number | MFCD00210588 |
| SMILES | COC1=C(Oc2cc(O)cc(O)c2C1=O)c3ccc(O)c(O)c3 |
| InChI | 1S/C16H12O7/c1-22-16-14(21)13-11(20)5-8(17)6-12(13)23-15(16)7-2-3-9(18)10(19)4-7/h2-6,17-20H,1H3 |
| InChI Key | WEPBGSIAWZTEJR-UHFFFAOYSA-N |
| Beilstein/REAXYS | 324509 |
| NACRES Code | NA.32 |
| UNSPSC | 12352202 |
| Hazard Symbols | transportation |
| MSDS | msds/66376_1_1486_70_0.pdf |
| Bioactivity | 3-O-Methylquercetin (3-MQ), a main constituent of Rhamnus nakaharai, inhibits total cAMP and cGMP-phosphodiesterase (PDE) of guinea pig trachealis. 3-O-Methylquercetin (3-MQ) exhibits IC50 values of 31.9 μM， 86.9 μM， 18.6 μM and 1.6 μM for PDE1, PDE5, PDE2 and PDE4, respectively[1]. Related Catalog Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphodiesterase (PDE) Research Areas >> Inflammation/Immunology References [1]. Wun-Chang Ko, et al. 3-O-methylquercetin More Selectively Inhibits Phosphodiesterase Subtype 3. Planta Med. 2003 Apr;69(4):310-5. Chemical & Physical Properties Density 1.7±0.1 g/cm3 Boiling Point 643.0±55.0 °C at 760 mmHg Molecular Formula C16H12O7 Molecular Weight 316.262 Flash Point 244.7±25.0 °C Exact Mass 316.058289 PSA 120.36000 LogP 2.02 Vapour Pressure 0.0±2.0 mmHg at 25°C Index of Refraction 1.762 InChIKey WEPBGSIAWZTEJR-UHFFFAOYSA-N SMILES COc1c(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c2c1=O |
| Use of | 3-O-Methylquercetin (3-MQ), a main constituent of Rhamnus nakaharai, inhibits total cAMP and cGMP-phosphodiesterase (PDE) of guinea pig trachealis. 3-O-Methylquercetin (3-MQ) exhibits IC50 values of 31.9 μM， 86.9 μM， 18.6 μM and 1.6 μM for PDE1, PDE5, PDE2 and PDE4, respectively[1]. Properties Name 3',4',5,7-tetrahydroxy-3-methoxyflavone Synonym More Synonyms 3-O-Methylquercetin Biological Activity Description 3-O-Methylquercetin (3-MQ), a main constituent of Rhamnus nakaharai, inhibits total cAMP and cGMP-phosphodiesterase (PDE) of guinea pig trachealis. 3-O-Methylquercetin (3-MQ) exhibits IC50 values of 31.9 μM， 86.9 μM， 18.6 μM and 1.6 μM for PDE1, PDE5, PDE2 and PDE4, respectively[1]. Related Catalog Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphodiesterase (PDE) Research Areas >> Inflammation/Immunology References [1]. Wun-Chang Ko, et al. 3-O-methylquercetin More Selectively Inhibits Phosphodiesterase Subtype 3. Planta Med. 2003 Apr;69(4):310-5. Chemical & Physical Properties Molecular Formula C16H12O7 Exact Mass 316.058289 PSA 120.36000 Index of Refraction 1.762 InChIKey WEPBGSIAWZTEJR-UHFFFAOYSA-N |
| Tax Rebate | 9.0% |
| Supervision | None MFN tariff: 5.5% Ordinary tariff: 30.0% |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Dangerous Regulations for land transport: 2811 International Dangerous Regulations for sea transport: 2811 International Dangerous Regulations for air transport: 2811 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: TOXIC SOLID, ORGANIC, N.O.S. (3-O-Methylquercetin) IMDG: TOXIC SOLID, ORGANIC, N.O.S. (3-O-Methylquercetin) International air transport hazard regulations: Toxic solid, organic, n.o.s. (3-O-Methylquercetin) 14.3 Transport hazard categories European Land Transport Danger Regulations: 6.1 International Maritime Transport Danger Regulations: 6.1 International Air Transport Danger Regulations: 6.1 14.4 Package group European Land Transport Danger Regulations: III International Maritime Transport Danger Regulations: III International Air Transport Danger Regulations: III 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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