CAS Number703-95-7
SynonymsEINECS 211-876-0; 5-Fluoro-6-carboxyuracil; 5-Fluoro orotic acid; 5-Fluoro-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid; MFCD00042526; 5-Fluoro-2,6-dioxo-1,2,3,6-tetrahydro-4-pyrimidinecarboxylic acid; 5-Fluoroorotic acid; 5-Fluoroorotic acid monohydrate
Molecular FormulaC5H3O4N2F1
Molecular Weight174.09
Purity98%
Density1.8±0.1 g/cm3
Melting Point278 °C (dec.)(lit.)
AppearanceLight yellow or reddish yellow, crystal or powder
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 703-95-7 |
| Catalog No. | 2A-9006546 |
| Chinese Name | 5-氟乳清酸 |
| Synonyms | EINECS 211-876-0; 5-Fluoro-6-carboxyuracil; 5-Fluoro orotic acid; 5-Fluoro-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid; MFCD00042526; 5-Fluoro-2,6-dioxo-1,2,3,6-tetrahydro-4-pyrimidinecarboxylic acid; 5-Fluoroorotic acid; 5-Fluoroorotic acid monohydrate |
| Molecular Formula | C5H3O4N2F1 |
| Molecular Weight | 174.09 |
| Purity | 98 |
| Density | 1.8±0.1 g/cm3 |
| Melting Point | 278 °C (dec.)(lit.) |
| Appearance | Light yellow or reddish yellow, crystal or powder |
| Water Solubility | NH4OH 4 M: 50 mg/mL, clear, faintly yellow |
| Storage Condition | Store in an airtight container in a cool, dry plac |
| Application | 5-Fluoroorotic is a selective agent in yeast molecular genetics. 5-Fluoroorotic has anticancer effects close to those of 5-fluorocytosine and moderate antidermatophytes. |
| HTC | 2933599090 |
| MDL Number | MFCD00223679 |
| SMILES | O=C(O)c1[nH]c(=O)[nH]c(=O)c1F |
| InChI | InChI=1S/C5H3FN2O4/c6-1-2(4(10)11)7-5(12)8-3(1)9/h(H,10,11)(H2,7,8,9,12) |
| InChI Key | SEHFUALWMUWDKS-UHFFFAOYSA-N |
| Hazard Symbols | Transport |
| MSDS | msds/6546_1_703_95_7.pdf |
| Bioactivity | 5-Fluoroorotic is a selective agent in yeast molecular genetics. 5-Fluoroorotic possesses a well-expressed anticandidal effect close to that of 5-fluorocytosine, as well as moderate antidermatophytal effects[1][2]. Related Catalog Research Areas >> Cancer Research Areas >> Infection Signaling Pathways >> Others >> Others References [1]. Boeke JD, et, al. 5-Fluoroorotic acid as a selective agent in yeast molecular genetics. Methods Enzymol. 1987; 154: 164-75. [2]. Nikolova K, et, al. Studies on the antimycotic activity of 5-fluoroorotic acid. Methods Find Exp Clin Pharmacol. 1987 Feb; 9(2): 85-9. Chemical & Physical Properties Density 1.8±0.1 g/cm3 Melting Point 278 °C (dec.)(lit.) Molecular Formula C5H3FN2O4 Molecular Weight 174.087 Exact Mass 174.007690 PSA 103.02000 LogP -1.00 Index of Refraction 1.580 InChIKey SEHFUALWMUWDKS-UHFFFAOYSA-N SMILES O=C(O)c1[nH]c(=O)[nH]c(=O)c1F Storage condition −20°C Water Solubility NH4OH 4 M: 50 mg/mL, clear, faintly yellow |
| Use of | 5-Fluoroorotic is a selective agent in yeast molecular genetics. 5-Fluoroorotic possesses a well-expressed anticandidal effect close to that of 5-fluorocytosine, as well as moderate antidermatophytal effects[1][2]. Properties Name 5-Fluoroorotic Acid Synonym More Synonyms 5-Fluoroorotic acid Biological Activity Description 5-Fluoroorotic is a selective agent in yeast molecular genetics. 5-Fluoroorotic possesses a well-expressed anticandidal effect close to that of 5-fluorocytosine, as well as moderate antidermatophytal effects[1][2]. Related Catalog Research Areas >> Cancer Research Areas >> Infection Signaling Pathways >> Others >> Others References [1]. Boeke JD, et, al. 5-Fluoroorotic acid as a selective agent in yeast molecular genetics. Methods Enzymol. 1987; 154: 164-75. [2]. Nikolova K, et, al. Studies on the antimycotic activity of 5-fluoroorotic acid. Methods Find Exp Clin Pharmacol. 1987 Feb; 9(2): 85-9. Chemical & Physical Properties Molecular Formula C5H3FN2O4 Exact Mass 174.007690 PSA 103.02000 LogP -1.00 Index of Refraction 1.580 InChIKey SEHFUALWMUWDKS-UHFFFAOYSA-N SMILES O=C(O)c1[nH]c(=O)[nH]c(=O)c1F |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available The above information is believed to be correct, but is not all-inclusive and should be used as a guide only. The information in this document is based on our current knowledge and is Correct safety instructions apply to this product. This information does not represent a warranty as to the properties of this product. See reverse side of invoice or packing slip. |
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