CAS Number66335-38-4
Synonyms5'-deoxy-5-fluoro-Cytidine; 5'-Deoxy-5-fluorocytidine; MFCD07369278; 4-Amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methyltetrahydro-2-furanyl]-5-fluoro-2(1H)-pyrimidinone; 5'-Deoxy-5-fluoro Cytidine
Molecular FormulaC9H12FN3O4
Molecular Weight245.21
Purity98%
Density1.8±0.1 g/cm3
Boiling Point437.9±55.0 °C at 760 mmHg
Melting Point196-198ºC
Appearancewhite solid
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 66335-38-4 |
| Catalog No. | 2A-9006541 |
| Chinese Name | 5'-脱氧-5-氟胞嘧啶核苷 |
| Synonyms | 5'-deoxy-5-fluoro-Cytidine; 5'-Deoxy-5-fluorocytidine; MFCD07369278; 4-Amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methyltetrahydro-2-furanyl]-5-fluoro-2(1H)-pyrimidinone; 5'-Deoxy-5-fluoro Cytidine |
| Molecular Formula | C9H12FN3O4 |
| Molecular Weight | 245.21 |
| Purity | 98 |
| Density | 1.8±0.1 g/cm3 |
| Boiling Point | 437.9±55.0 °C at 760 mmHg |
| Melting Point | 196-198ºC |
| Appearance | white solid |
| Storage Condition | Hygroscopic, -20°C Freezer, Under Inert Atmosphere |
| Application | 5-Fluoro-5'-deoxycytidine is a cytidine analog. Cytidine analogues have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420) and have potential anti-metabolic and anti-tumor |
| HTC | 2934999090 |
| MDL Number | MFCD07369278 |
| SMILES | Fc1c[n]([c](nc1N)=O)[C@@H]2O[C@@H]([C@H]([C@H]2O)O)C |
| InChI | 1S/C9H12FN3O4/c1-3-5(14)6(15)8(17-3)13-2-4(10)7(11)12-9(13)16/h2-3,5-6,8,14-15H,1H3,(H2,11,12,16)/t3-,5-,6-,8-/m1/s1 |
| InChI Key | YSNABXSEHNLERR-ZIYNGMLESA-N |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| MSDS | msds/6541_1_66335_38_4.pdf |
| Bioactivity | 5-Fluoro-5'-deoxycytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog References [1]. Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3(11):1062-8. Chemical & Physical Properties Density 1.8±0.1 g/cm3 Boiling Point 437.9±55.0 °C at 760 mmHg Melting Point 196-198ºC Molecular Formula C9H12FN3O4 Molecular Weight 245.21 Flash Point 218.6±31.5 °C Exact Mass 245.081177 PSA 110.60000 LogP -0.94 Vapour Pressure 0.0±2.4 mmHg at 25°C Index of Refraction 1.700 InChIKey YSNABXSEHNLERR-ZIYNGMLESA-N SMILES CC1OC(n2cc(F)c(N)nc2=O)C(O)C1O Storage condition Hygroscopic, -20°C Freezer, Under Inert Atmosphere |
| Use of | 5-Fluoro-5'-deoxycytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1]. Properties Name 5'-Deoxy-5-fluorocytidine Synonym More Synonyms 5'-Deoxy-5-fluorocytidine Biological Activity Description 5-Fluoro-5'-deoxycytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog References [1]. Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3(11):1062-8. Chemical & Physical Properties Molecular Formula C9H12FN3O4 Exact Mass 245.081177 PSA 110.60000 LogP -0.94 Index of Refraction 1.700 InChIKey YSNABXSEHNLERR-ZIYNGMLESA-N |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information United Nations classification: inconsistent with United Nations classification standards UN number: not specified |
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