
CAS Number1071-37-0
SynonymsMFCD00012585; Ethiron; S-ethylisothiouronium hydrobromate; S-Ethylisothio Urea,Hydrobromide; Ethyl carbamimidothioate hydrobromide (1:1); Ethiron bromide; USAF EL-18; S-ethylthiouronium bromide; 2-Ethyl-2-isothiourea hydrobromide; S-Ethylisothiuronium bromide; S-Ethylthiuronium bromide; 2-Ethyl-2-thiopseudourea hydrobromide; 2-ethyl isothiourea hydrobromide; Carbamimidothioic acid, ethyl ester, hydrobromide (1:1); Bromide S-ethylisothiuronium; etiron; S-Ethylisothiouronium hydrobromide; ethyl imidothiocarbamate hydrobromide; S-ETHYLISOTHIOUREA HYDROBROMIDE
Molecular FormulaC3H9BrN2S
Molecular Weight185.09
Density1.19 g/cm3
Boiling Point159.6ºC at 760 mmHg
Melting Point79-81°C
AppearanceWhite crystalline solid
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 1071-37-0 |
| Catalog No. | 2A-9064085 |
| Chinese Name | S-乙基异硫脲氢溴酸盐 |
| Synonyms | MFCD00012585; Ethiron; S-ethylisothiouronium hydrobromate; S-Ethylisothio Urea,Hydrobromide; Ethyl carbamimidothioate hydrobromide (1:1); Ethiron bromide; USAF EL-18; S-ethylthiouronium bromide; 2-Ethyl-2-isothiourea hydrobromide; S-Ethylisothiuronium bromide; S-Ethylthiuronium bromide; 2-Ethyl-2-thiopseudourea hydrobromide; 2-ethyl isothiourea hydrobromide; Carbamimidothioic acid, ethyl ester, hydrobromide (1:1); Bromide S-ethylisothiuronium; etiron; S-Ethylisothiouronium hydrobromide; ethyl imidothiocarbamate hydrobromide; S-ETHYLISOTHIOUREA HYDROBROMIDE |
| Molecular Formula | C3H9BrN2S |
| Molecular Weight | 185.09 |
| Density | 1.19 g/cm3 |
| Boiling Point | 159.6ºC at 760 mmHg |
| Melting Point | 79-81°C |
| Appearance | White crystalline solid |
| Storage Condition | Store airtight at 2-8°C |
| Application | S-EIT (hydrobromide) is a biochemical reagent that can be used as a biological material or organic compound for life science-related research. |
| HTC | 2930909090 |
| SMILES | Br.CCSC(=N)N |
| InChI | InChI=1S/C3H8N2S.Br/c1-2-6-3(4)5;/h2H2,1H3,(H3,4,5); |
| InChI Key | SWXXKWPYNMZFTE-UHFFFAOYSA-N |
| Hazard Symbols | transportation |
| MSDS | msds/64085_2_1071_37_0.pdf |
| Bioactivity | S-EIT (hydrobromide) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Related Catalog Research Areas >> Others In Vitro EIT (S-ethylisothiourea) Hydrobromide is a selective inhibitor of type II NOS. EIT produced a dose-dependent and >95% inhibition of LPS-induced increases in plasma [NOx]. The ED50 value of EIT is 0.4 mg/kg. Pretreatment with L-arginine (but not D-arginine) prevented mortality without affecting type II NOS-dependent NO production, suggesting that toxicity may be due to inhibition of one of the other NOS isoforms (endothelial or neuronal) [1]. Selective NOS II antagonists attenuate but do not block shear stress-induced vasodilation in fetal lungs. Stimulation of NOS II activity, possibly from smooth muscle cells, partially contributes to the NO-mediated decrease in PVR (pulmonary vascular resistance) during shear stress-induced pulmonary vasodilation. Splenocytes stimulated with alloantigens in the presence of AMT or another selective iNOS inhibitor, S-ethylisothiourea (EIT), produced more interleukin (IL)-4 and IL-10 than cells stimulated in the absence of the iNOS inhibitor. Production of the Th1 cytokines IL-2 and interferon (IFN)-γ was not enhanced by inhibition of NO synthesis. Acute administration of EIT (380 nmol/h), another selective inhibitor of inducible nitric oxide synthase, also attenuated the pregnancy-induced increases in glomerular filtration rate and effective renal plasma flow. Chemical & Physical Properties Density 1.19 g/cm3 Boiling Point 159.6ºC at 760 mmHg Melting Point 79-81°C Molecular Formula C3H9BrN2S Molecular Weight 185.09 Flash Point 50.3ºC Exact Mass 183.966980 PSA 75.17000 LogP 2.39110 Vapour Pressure 2.26mmHg at 25°C Index of Refraction 1.548 InChIKey SWXXKWPYNMZFTE-UHFFFAOYSA-N SMILES Br.CCSC(=N)N Storage condition 2-8°C |
| Use of | S-EIT (hydrobromide) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Properties Articles27 Name ethyl carbamimidothioate,hydrobromide Synonym More Synonyms Biological Activity Description S-EIT (hydrobromide) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Related Catalog Research Areas >> Others Chemical & Physical Properties Molecular Formula C3H9BrN2S Exact Mass 183.966980 PSA 75.17000 LogP 2.39110 Index of Refraction 1.548 InChIKey SWXXKWPYNMZFTE-UHFFFAOYSA-N SMILES Br.CCSC(=N)N |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 30.0% |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: No dangerous goods IMDG Code: No dangerous goods International Air Transport Dangerous Regulations: No dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special precautions for users No data available |
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