CAS Number81-61-8
Synonyms1,2,5,8-tetrahydroxy-9,10-anthracenedione; Alizarinbordeaux; MFCD00001205; 9,10-Anthracenedione,1,2,5,8-tetrahydroxy; Alizarine Bordeaux B; 1,2,5,8-Tetrahydroxy-9,10-anthraquinone; Mordant Violet 26; Khinalizarin; Alizarine Bordeaux; C.I. Mordant Violet 26; Alizarin bordeaux B; 1,2,5,8-tetrahydroxyanthracene-9,10-dione; Quinalizarin; 1,2,5,8-tetrahydroxyanthraquinone; EINECS 201-366-6
Molecular FormulaC14H8O6
Molecular Weight272.21
Purity≥95 (HPLC)%
Density1.8±0.1 g/cm3
Boiling Point517.1±45.0 °C at 760 mmHg
Melting Point≥300 °C
Appearancepowder
EINECS201-366-6
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 81-61-8 |
| Catalog No. | 2A-9062633 |
| Chinese Name | 醌茜素 |
| Synonyms | 1,2,5,8-tetrahydroxy-9,10-anthracenedione; Alizarinbordeaux; MFCD00001205; 9,10-Anthracenedione,1,2,5,8-tetrahydroxy; Alizarine Bordeaux B; 1,2,5,8-Tetrahydroxy-9,10-anthraquinone; Mordant Violet 26; Khinalizarin; Alizarine Bordeaux; C.I. Mordant Violet 26; Alizarin bordeaux B; 1,2,5,8-tetrahydroxyanthracene-9,10-dione; Quinalizarin; 1,2,5,8-tetrahydroxyanthraquinone; EINECS 201-366-6 |
| Molecular Formula | C14H8O6 |
| Molecular Weight | 272.21 |
| Purity | ≥95 (HPLC) |
| Density | 1.8±0.1 g/cm3 |
| Boiling Point | 517.1±45.0 °C at 760 mmHg |
| Melting Point | ≥300 °C |
| Appearance | powder |
| Storage Condition | This product should be sealed and stored in a dry |
| Application | Quinalidine is a potent, selective and cell-permeable protein kinase CK2 inhibitor with a Ki of approximately 50 nM and an IC50 of 110 nM. Quinalidine can induce apoptosis in some cancer cells [1]. |
| EINECS | 201-366-6 |
| PubChem ID | 329823863 |
| MDL Number | MFCD00001205 |
| SMILES | Oc1ccc2C(=O)c3c(O)ccc(O)c3C(=O)c2c1O |
| InChI | 1S/C14H8O6/c15-6-3-4-7(16)11-10(6)12(18)5-1-2-8(17)13(19)9(5)14(11)20/h1-4,15-17,19H |
| InChI Key | VBHKTXLEJZIDJF-UHFFFAOYSA-N |
| Beilstein/REAXYS | 1889617 |
| NACRES Code | NA.77 |
| UNSPSC | 12171500 |
| Hazard Symbols | transportation |
| MSDS | msds/62633_1_81_61_8.pdf |
| Bioactivity | Quinalizarin is a potent, selective and cell-permeable protein kinase CK2 inhibitor with an Ki of ~50 nM and an IC50 of 110 nM. Quinalizarin can induce apoptosis of certain cancer cells[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Casein Kinase Signaling Pathways >> Stem Cell/Wnt >> Casein Kinase Target CK2:~50 nM (Ki) CK2:110 nM (IC50) References [1]. Cozza G, et al. Quinalizarin as a potent, selective and cell-permeable inhibitor of protein kinase CK2. Biochem J. 2009;421(3):387-395. Published 2009 Jul 15. Chemical & Physical Properties Density 1.8±0.1 g/cm3 Boiling Point 517.1±45.0 °C at 760 mmHg Melting Point 99 °C Molecular Formula C14H8O6 Molecular Weight 272.210 Flash Point 280.6±25.2 °C Exact Mass 272.032074 PSA 115.06000 LogP 5.18 Vapour Pressure 0.0±1.4 mmHg at 25°C Index of Refraction 1.815 InChIKey VBHKTXLEJZIDJF-UHFFFAOYSA-N SMILES O=C1c2ccc(O)c(O)c2C(=O)c2c(O)ccc(O)c21 Storage condition room temp |
| Use of | Quinalizarin is a potent, selective and cell-permeable protein kinase CK2 inhibitor with an Ki of ~50 nM and an IC50 of 110 nM. Quinalizarin can induce apoptosis of certain cancer cells[1]. Properties Name quinalizarin Synonym More Synonyms Quinalizarin Biological Activity Description Quinalizarin is a potent, selective and cell-permeable protein kinase CK2 inhibitor with an Ki of ~50 nM and an IC50 of 110 nM. Quinalizarin can induce apoptosis of certain cancer cells[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Casein Kinase Signaling Pathways >> Stem Cell/Wnt >> Casein Kinase CK2:~50 nM (Ki) CK2:110 nM (IC50) References [1]. Cozza G, et al. Quinalizarin as a potent, selective and cell-permeable inhibitor of protein kinase CK2. Biochem J. 2009;421(3):387-395. Published 2009 Jul 15. Chemical & Physical Properties Molecular Formula C14H8O6 Exact Mass 272.032074 PSA 115.06000 Index of Refraction 1.815 InChIKey VBHKTXLEJZIDJF-UHFFFAOYSA-N Storage condition room temp |
| Transport Info | Product name: Purity: 95.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Danger Regulations: 3077 International Maritime Transport Danger Regulations: 3077 International Air Transport Danger Regulations: 3077 14.2 Names specified by the United Nations (UN) European land transport hazard regulations: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (1,2,5,8- Tetrahydroxyanthraquinone) IMDG Code: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (1,2,5,8- Tetrahydroxyanthraquinone) International air transport hazard regulations: Environmentally hazardous substance, solid, n.o.s. (1,2,5,8-Tetrahydroxyanthraquinone) 14.3 Transport hazard categories European land transport Dangerous Regulations: 9 International sea transport Dangerous Regulations: 9 International air transport Dangerous Regulations: 9 14.4 Package group European Land Transport Danger Regulations: III International Maritime Transport Danger Regulations: III International Air Transport Danger Regulations: III 14.5 Environmental hazards European Land Transport Dangerous Regulations: Yes International Maritime Transport Dangerous Regulations Maritime Pollutants: Yes International Air Transport Dangerous Regulations: Yes 14.6 Special reminder to users further information Dangerous goods are individually packaged, with liquids exceeding 5 liters or solids exceeding 5 kilograms. The outer packaging of each independent package and the combined independent inner package must have EHS on it. Identification (according to European ADR Regulation 2.2.9.1.10, IMDG Regulation 2.10.3), |
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