| Chemical & Physical Properties | |
|---|---|
| CAS Number | 218457-67-1 |
| Catalog No. | 2A-9006245 |
| Chinese Name | 6-[4-(叔丁基)苯氧基]吡啶-3-胺 |
| Synonyms | 5-Amino-2-(4-tert-butylphenoxy)pyridine; 6-(4-(tert-Butyl)phenoxy)pyridin-3-amine; MFCD00052647 |
| Molecular Formula | C15H18N2O |
| Molecular Weight | 242.32 |
| Purity | ≥97 (HPLC) |
| Density | 1.09g/cm3 |
| Boiling Point | 394.2ºC at 760mmHg |
| Melting Point | 89-90ºC |
| Appearance | powder |
| Storage Condition | 2-8°C, sealed, dry |
| Application | CB-103 is a notch signaling pathway inhibitor developed for cancer treatment. For detailed information, please refer to the patent document US9296682B2. |
| HTC | 2933399090 |
| MDL Number | MFCD00052647 |
| SMILES | Nc1cnc(cc1)Oc2ccc(cc2)C(C)(C)C |
| InChI | 1S/C15H18N2O/c1-15(2,3)11-4-7-13(8-5-11)18-14-9-6-12(16)10-17-14/h4-10H,16H2,1-3H3 |
| InChI Key | WHIWGRCYMQLLAO-UHFFFAOYSA-N |
| NACRES Code | NA.77 |
| UNSPSC | 12352200 |
| MSDS | msds/6245_1_218457_67_1.pdf |
| Bioactivity | CB-103 is a notch signaling pathway inhibitor extracted from patent US9296682B2. CB-103 is developed for the treatment of cancers[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> Stem Cell/Wnt >> Notch References [1]. Freddy Radtke, et al. Inhibitors of notch signalling pathway and use thereof in treatment of cancers. US9296682B2. Chemical & Physical Properties Density 1.09g/cm3 Boiling Point 394.2ºC at 760mmHg Melting Point 89-90ºC Molecular Formula C15H18N2O Molecular Weight 242.31600 Flash Point 192.2ºC Exact Mass 242.14200 PSA 48.14000 LogP 4.33480 Vapour Pressure 2.01E-06mmHg at 25°C Index of Refraction 1.574 InChIKey WHIWGRCYMQLLAO-UHFFFAOYSA-N SMILES CC(C)(C)c1ccc(Oc2ccc(N)cn2)cc1 |
| Use of | Properties Name 6-(4-tert-butylphenoxy)pyridin-3-amine Synonym More Synonyms 5-AMINO-2-(4-TERT-BUTYLPHENOXY)PYRIDINE Biological Activity Related Catalog Research Areas >> Cancer Signaling Pathways >> Stem Cell/Wnt >> Notch References [1]. Freddy Radtke, et al. Inhibitors of notch signalling pathway and use thereof in treatment of cancers. US9296682B2. Chemical & Physical Properties Molecular Formula C15H18N2O Exact Mass 242.14200 PSA 48.14000 LogP 4.33480 Index of Refraction 1.574 InChIKey WHIWGRCYMQLLAO-UHFFFAOYSA-N |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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