CAS Number7728-40-7
Synonymsmonoethylglycine-2,6-xylidide; monoethyl glycine xylidide; MEGX; N-Ethylglycinexylidide; ethylaminoacet-2,6-xylidide; L 86; Ethylglycylxylidide; desmethyllidocaine; 2-ethylamino-2',6'-dimethylacetanilide; Norlidocaine; 2-Ethylamino-2,6-acetoxylidine; 2-Ethylamino-2',6'-acetoxylidide; N-(2,6-dimethylphenyl)-2-(ethylamino)acetamide
Molecular FormulaC12H18N2O
Molecular Weight206.28
Purity≥95 (HPLC)%
Density1.047g/cm3
Boiling Point335.6ºC at 760 mmHg
Melting Point242-245ºC
Appearancepowder
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 7728-40-7 |
| Catalog No. | 2A-9062063 |
| Chinese Name | 去乙基利多卡因 |
| Synonyms | monoethylglycine-2,6-xylidide; monoethyl glycine xylidide; MEGX; N-Ethylglycinexylidide; ethylaminoacet-2,6-xylidide; L 86; Ethylglycylxylidide; desmethyllidocaine; 2-ethylamino-2',6'-dimethylacetanilide; Norlidocaine; 2-Ethylamino-2,6-acetoxylidine; 2-Ethylamino-2',6'-acetoxylidide; N-(2,6-dimethylphenyl)-2-(ethylamino)acetamide |
| Molecular Formula | C12H18N2O |
| Molecular Weight | 206.28 |
| Purity | ≥95 (HPLC) |
| Density | 1.047g/cm3 |
| Boiling Point | 335.6ºC at 760 mmHg |
| Melting Point | 242-245ºC |
| Appearance | powder |
| Storage Condition | 2-8°C |
| Application | Monoethylglycinimide is a metabolite of lidocaine (HY-B0185), which oxidizes N-deethylation of lignin through liver cytochrome P-450 enzyme [1]. |
| HTC | 2924299090 |
| PubChem ID | 329825147 |
| MDL Number | MFCD00098991 |
| SMILES | CC1=C(NC(CNCC)=O)C(C)=CC=C1 |
| InChI | 1S/C12H18N2O/c1-4-13-8-11(15)14-12-9(2)6-5-7-10(12)3/h5-7,13H,4,8H2,1-3H3,(H,14,15) |
| InChI Key | WRMRXPASUROZGT-UHFFFAOYSA-N |
| NACRES Code | NA.77 |
| UNSPSC | 12352200 |
| MSDS | msds/62063_1_7728_40_7.pdf |
| Bioactivity | Monoethylglycinexylidide is a metabolite of Lidocain (HY-B0185) via oxidative N-deethylation of Lignocaine by liver cytochrome P-450 enzymes in the liver[1]. Related Catalog Research Areas >> Inflammation/Immunology Research Areas >> Metabolic Disease References [1]. Y S Huang, et al. Measuring lidocaine metabolite--monoethylglycinexylidide as a quantitative index of hepatic function in adults with chronic hepatitis and cirrhosis. J Hepatol. 1993 Aug;19(1):140-7. Chemical & Physical Properties Density 1.047g/cm3 Boiling Point 335.6ºC at 760 mmHg Melting Point 242-245ºC Molecular Formula C12H18N2O Molecular Weight 206.28 Flash Point 127.8ºC Exact Mass 206.14200 PSA 41.13000 LogP 2.31530 Index of Refraction 1.553 InChIKey WRMRXPASUROZGT-UHFFFAOYSA-N SMILES CCNCC(=O)Nc1c(C)cccc1C Storage condition 2-8°C |
| Use of | Monoethylglycinexylidide is a metabolite of Lidocain (HY-B0185) via oxidative N-deethylation of Lignocaine by liver cytochrome P-450 enzymes in the liver[1]. Properties Articles31 Name monoethylglycinexylidide Synonym More Synonyms Monoethylglycinexylidide Biological Activity Description Monoethylglycinexylidide is a metabolite of Lidocain (HY-B0185) via oxidative N-deethylation of Lignocaine by liver cytochrome P-450 enzymes in the liver[1]. Related Catalog Research Areas >> Inflammation/Immunology Research Areas >> Metabolic Disease References [1]. Y S Huang, et al. Measuring lidocaine metabolite--monoethylglycinexylidide as a quantitative index of hepatic function in adults with chronic hepatitis and cirrhosis. J Hepatol. 1993 Aug;19(1):140-7. Chemical & Physical Properties Molecular Formula C12H18N2O Exact Mass 206.14200 PSA 41.13000 LogP 2.31530 Index of Refraction 1.553 InChIKey WRMRXPASUROZGT-UHFFFAOYSA-N |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 30.0% |
| Transport Info | Product name: Summary 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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