CAS Number728-86-9
Synonymsfxffr dvr; Phenyl[4-(trifluoromethyl)phenyl]methanone; EINECS 211-974-3; (4-(trifluoromethyl)phenyl)(phenyl)methanone; p-Trifluoromethylbenzophenone; 4-(Trifluoromethyl)benzophenone; MFCD00000400; phenyl 4-(trifluoromethyl)phenyl ketone; (4-trifluoromethyl)(phenyl)methanone
Molecular FormulaC14H9O1F3
Molecular Weight250.22
Purity98%
Density1.244g/cm3
Boiling Point309.2ºC at 760 mmHg
Melting Point114-116 °C(lit.)
AppearanceOff-white to beige crystalline solid
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 728-86-9 |
| Catalog No. | 2A-9006140 |
| Chinese Name | 4-(三氟甲基)二苯甲酮 |
| Synonyms | fxffr dvr; Phenyl[4-(trifluoromethyl)phenyl]methanone; EINECS 211-974-3; (4-(trifluoromethyl)phenyl)(phenyl)methanone; p-Trifluoromethylbenzophenone; 4-(Trifluoromethyl)benzophenone; MFCD00000400; phenyl 4-(trifluoromethyl)phenyl ketone; (4-trifluoromethyl)(phenyl)methanone |
| Molecular Formula | C14H9O1F3 |
| Molecular Weight | 250.22 |
| Purity | 98 |
| Density | 1.244g/cm3 |
| Boiling Point | 309.2ºC at 760 mmHg |
| Melting Point | 114-116 °C(lit.) |
| Appearance | Off-white to beige crystalline solid |
| Storage Condition | Keep container tightly closed and stored in a cool |
| Application | 11β-HSD1-IN-7 (compound c10a) is an 11β-HSD1 inhibitor with an IC50 value of 1.9 μM for human 11β-HDD1. 11β-HHS1-IN-7 can be used in research on diabetes and cognitive decline [1]. |
| HTC | 2914700090 |
| MDL Number | MFCD00000400 |
| SMILES | FC(F)(F)c1ccc(cc1)C(=O)c2ccccc2 |
| InChI | InChI=1S/C14H9F3O/c15-14(16,17)12-8-6-11(7-9-12)13(18)10-4-2-1-3-5-10/h1-9H |
| InChI Key | InChIKey=OHTYZZYAMUVKQS-UHFFFAOYSA-N |
| MSDS | msds/6140_1_728_86_9.pdf |
| Bioactivity | 11β-HSD1-IN-7 (compound c10a) is a 11β‑HSD1 inhibitor with an IC50 value of 1.9 μM for human 11β‑HSD1. 11β-HSD1-IN-7 can be used for the research of diabetes and cognitive decline[1]. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease Research Areas >> Neurological Disease Target IC50: 1.9 μM (human 11β‑HSD1)[1] In Vitro 11β-HSD1-IN-7 (0-50 μM) inhibits human and rat 11β‑HSD1 with IC50 values of 1.9 μM and ＞50 μM, respectively[1]. Chemical & Physical Properties Density 1.244g/cm3 Boiling Point 309.2ºC at 760 mmHg Melting Point 114-116 °C(lit.) Molecular Formula C14H9F3O Molecular Weight 250.21600 Flash Point 153ºC Exact Mass 250.06100 PSA 17.07000 LogP 3.93640 Index of Refraction 1.519 |
| Use of | Properties Name phenyl-[4-(trifluoromethyl)phenyl]methanone Synonym More Synonyms 4-(trifluoromethyl)benzophenone Biological Activity Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease Research Areas >> Neurological Disease IC50: 1.9 μM (human 11β‑HSD1)[1] In Vitro 11β-HSD1-IN-7 (0-50 μM) inhibits human and rat 11β‑HSD1 with IC50 values of 1.9 μM and ＞50 μM, respectively[1]. Chemical & Physical Properties Molecular Formula C14H9F3O Exact Mass 250.06100 PSA 17.07000 LogP 3.93640 Index of Refraction 1.519 |
| Tax Rebate | 9.0% |
| Supervision | None MFN tariff: 5.5% Ordinary tariff: 30.0% |
| Transport Info | Product name: Summary HS: 2914700090 halogenated, sulphonated, nitrated or nitrosated derivatives of ketones and quinones, whether or not with other oxygen function Tax rebate rate:9.0% Supervision conditions:none VAT:17.0% MFN tariff:5.5% General tariff:30.0% |
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