CAS Number74-79-3
SynonymsL-Arginine; MFCD00002635; H-L-ARG-OH; L-Argnie; (L)-Arginine; L-ARG-OH; L-arginie; AGRININE; arginine; L(+)-Arginine; FEMA 3819; EINECS 200-811-1; L-a-Amino-d-guanidinovaleric Acid; (2S)-2-Amino-5-carbamimidamidopentanoic acid; H-ARG-OH; S-(+)-2-Amino-5-[(aminoiminomethyl)amino]pentanoic acid; l-arginin; Arginine (VAN); l-arg; 5-[(Aminoiminomethyl)amino]-L-norvaline; Arg; N5-(Aminoiminomethyl)-L-ornithine
Molecular FormulaH2NC(=NH)NH(CH2)3CH(NH2)CO2H
Molecular Weight174.20
Purity98.5-101.0%
Density1.5±0.1 g/cm3
Boiling Point367.6±52.0 °C at 760 mmHg
Melting Point222 °C (dec.) (lit.)
Appearancepowder
EINECS200-811-1
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 74-79-3 |
| Catalog No. | 2A-9060981 |
| Chinese Name | L-精氨酸 |
| Synonyms | L-Arginine; MFCD00002635; H-L-ARG-OH; L-Argnie; (L)-Arginine; L-ARG-OH; L-arginie; AGRININE; arginine; L(+)-Arginine; FEMA 3819; EINECS 200-811-1; L-a-Amino-d-guanidinovaleric Acid; (2S)-2-Amino-5-carbamimidamidopentanoic acid; H-ARG-OH; S-(+)-2-Amino-5-[(aminoiminomethyl)amino]pentanoic acid; l-arginin; Arginine (VAN); l-arg; 5-[(Aminoiminomethyl)amino]-L-norvaline; Arg; N5-(Aminoiminomethyl)-L-ornithine |
| Molecular Formula | H2NC(=NH)NH(CH2)3CH(NH2)CO2H |
| Molecular Weight | 174.20 |
| Purity | 98.5-101.0 |
| Density | 1.5±0.1 g/cm3 |
| Boiling Point | 367.6±52.0 °C at 760 mmHg |
| Melting Point | 222 °C (dec.) (lit.) |
| Appearance | powder |
| Water Solubility | 148.7 g/L (20 ºC) |
| Storage Condition | Sealed packaging in brown glass bottles. Store in |
| Application | L-Arginine is a nitrogen donor for the synthesis of nitric oxide and a vasodilator. |
| EINECS | 200-811-1 |
| HTC | 2922499990 |
| PubChem ID | 24891316 |
| MDL Number | MFCD00002635 |
| SMILES | N[C@@H](CCCNC(N)=N)C(O)=O |
| InChI | 1S/C6H14N4O2/c7-4(5(11)12)2-1-3-10-6(8)9/h4H,1-3,7H2,(H,11,12)(H4,8,9,10)/t4-/m0/s1 |
| InChI Key | ODKSFYDXXFIFQN-BYPYZUCNSA-N |
| Beilstein/REAXYS | 1725413 |
| NACRES Code | NA.26 |
| eCl@ss | 32160406 |
| UNSPSC | 12352209 |
| Hazard Symbols | transportation |
| MSDS | msds/60981_1_74_79_3.pdf |
| Bioactivity | L-Arginine is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.Target: OthersL-Arginine is an α-amino acid. It was first isolated in 1886. The L-form is one of the 20 most common natural amino acids. At the level of molecular genetics, in the structure of the messenger ribonucleic acid mRNA, CGU, CGC, CGA, CGG, AGA, and AGG, are the triplets of nucleotide bases or codons that code for arginine during protein synthesis. In mammals, arginine is classified as a semiessential or conditionally essential amino acid, depending on the developmental stage and health status of the individual.L-Arginine is associated with a decrease in cardiac index while stroke index is maintained in patients with severe sepsis. Resolution of shock at 72 hours is achieved by 40% and 24% of the patients in the L-Arginine and placebo cohorts, respectively. L-Arginine (450 mg/kg during a 15-minute period) amplifies and sustains the hyperemia (38%) and increases absolute brain blood flow after eNOS upregulation by chronic simvastatin treatment (2 mg/kg subcutaneously, daily for 14 days) in SV-129 mice. Related Catalog Signaling Pathways >> Immunology/Inflammation >> NO Synthase Natural Products >> Others Research Areas >> Others Target Human Endogenous Metabolite References [1]. Tapiero H, et al. I. Arginine. Biomed Pharmacother. 2002 Nov;56(9):439-45. [2]. Bakker J, et al. Administration of the nitric oxide synthase inhibitor NG-methyl-L-arginine hydrochloride (546C88) by intravenous infusion for up to 72 hours can promote the resolution of shock in patients with severe sepsis: results of a randomized, double-blind, placebo-controlled multicenter study (study no. 144-002). Crit Care Med. 2004 Jan;32(1):1-12. [3]. Yamada M, et al. Endothelial nitric oxide synthase-dependent cerebral blood flow augmentation by L-arginine after chronic statin treatment. J Cereb Blood Flow Metab. 2000 Apr;20(4):709-17. Chemical & Physical Properties Density 1.5±0.1 g/cm3 Boiling Point 367.6±52.0 °C at 760 mmHg Melting Point 222 °C (dec.)(lit.) Molecular Formula C6H14N4O2 Molecular Weight 174.201 Flash Point 176.1±30.7 °C Exact Mass 174.111679 PSA 125.22000 LogP -1.79 Vapour Pressure 0.0±1.8 mmHg at 25°C Index of Refraction 1.601 InChIKey ODKSFYDXXFIFQN-BYPYZUCNSA-N SMILES NC(N)=NCCCC(N)C(=O)O Water Solubility 148.7 g/L (20 ºC) |
| Use of | Properties Articles396 Name L-arginine Synonym More Synonyms L-arginine Biological Activity Related Catalog Signaling Pathways >> Immunology/Inflammation >> NO Synthase Natural Products >> Others Research Areas >> Others Human Endogenous Metabolite References [1]. Tapiero H, et al. I. Arginine. Biomed Pharmacother. 2002 Nov;56(9):439-45. [3]. Yamada M, et al. Endothelial nitric oxide synthase-dependent cerebral blood flow augmentation by L-arginine after chronic statin treatment. J Cereb Blood Flow Metab. 2000 Apr;20(4):709-17. Chemical & Physical Properties Molecular Formula C6H14N4O2 Exact Mass 174.111679 PSA 125.22000 LogP -1.79 Index of Refraction 1.601 InChIKey ODKSFYDXXFIFQN-BYPYZUCNSA-N SMILES NC(N)=NCCCC(N)C(=O)O |
| Tax Rebate | 9.0% |
| Supervision | none |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: No dangerous goods IMDG Code: No dangerous goods International Air Transport Dangerous Regulations: No dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special precautions for users No data available |
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