![N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-[2-(2H-tetrazol-5-yl)pyridin-4-yl]pyrimidin-4-yl]-5-methyl-pyridine-2-sulfonamide structure, CAS 180384-56-9](/structures/80000/60807_1_180384_56_9.png)
CAS Number180384-56-9
SynonymsN-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-[2-(2H-tetrazol-5-yl)pyridin-4-yl]pyrimidin-4-yl]-5-methylpyridine-2-sulfonamide; N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-[2-(2H-tetrazol-5-yl)-4-pyridyl]pyrimidin-4-yl]-5-methyl-pyridine-2-sulfonamide; N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-[2-(2H-tetrazol-5-yl)-4-pyridyl]-4-pyrimidinyl]-5-methyl-2-pyridinesulfonamide; N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-[2-(2H-1,2,3,4-tetrazol-5-yl)pyridin-4-yl]pyrimidin-4-yl]-5-methyl-pyridine-2-sulfonamide; Clazosentan
Molecular FormulaC20H19O3N6S2F3
Molecular Weight512.54
Purity98%
Density1.485g/cm3
Boiling Point754.5ºC at 760 mmHg
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 180384-56-9 |
| Catalog No. | 2A-9060807 |
| Chinese Name | N-(2-(2-(1H-四唑-5-基)吡啶-4-基)-6-(2-羟基乙氧基)-5-(2-甲氧基苯氧基)嘧啶-4-基)-5-甲基吡啶-2-磺酰胺 |
| Synonyms | N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-[2-(2H-tetrazol-5-yl)pyridin-4-yl]pyrimidin-4-yl]-5-methylpyridine-2-sulfonamide; N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-[2-(2H-tetrazol-5-yl)-4-pyridyl]pyrimidin-4-yl]-5-methyl-pyridine-2-sulfonamide; N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-[2-(2H-tetrazol-5-yl)-4-pyridyl]-4-pyrimidinyl]-5-methyl-2-pyridinesulfonamide; N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-[2-(2H-1,2,3,4-tetrazol-5-yl)pyridin-4-yl]pyrimidin-4-yl]-5-methyl-pyridine-2-sulfonamide; Clazosentan |
| Molecular Formula | C20H19O3N6S2F3 |
| Molecular Weight | 512.54 |
| Purity | 98 |
| Density | 1.485g/cm3 |
| Boiling Point | 754.5ºC at 760 mmHg |
| Storage Condition | 2-8°C, sealed, dry |
| Application | Clazosentan (Ro 61-1790) is a selective endothelin a (ETA) receptor antagonist. Clazosentan inhibits ET-1-mediated vasoconstriction. Clazosentan prevents cerebral vasospasm and vasospasm-related cereb |
| MDL Number | MFCD35066924 |
| SMILES | COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C)cn2)nc(-c2ccnc(-c3nn[nH]n3)c2)nc1OCCO |
| InChI | InChI=1S/C25H23N9O6S/c1-15-7-8-20(27-14-15)41(36,37)32-24-21(40-19-6-4-3-5-18(19)38-2)25(39-12-11-35)29-22(28-24)16-9-10-26-17(13-16)23-30-33-34-31-23/h3-10,13-14,35H,11-12H2,1-2H3,(H,28,29,32)(H,30,31,33,34) |
| InChI Key | LFWCJABOXHSRGC-UHFFFAOYSA-N |
| MSDS | msds/60807_1_180384_56_9.pdf |
| Transport Info | Product Name: Clazosentan Soudium |
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