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(2-AMINOETHOXY)DIPHENYLBORANE structure, CAS 524-95-8

(2-AMINOETHOXY)DIPHENYLBORANE

CAS Number524-95-8

Synonyms2-Aminoethoxydiphenylborane; Borinic acid, B,B-diphenyl-, 2-aminoethyl ester; Natural Product Reagent A; 2-diphenylboranyloxyethanamine; 2-Aminoethoxydiphenyl borate,2-APB,2-Aminoethyl diphenyl borate; Diphenylborinic Acid Ethanolamine Ester; EINECS 208-366-5; Diphenylborinic Acid 2-Aminoethyl Ester; 2-Aminoethyldiphenylborinate; 2-Aminoethyl diphenylborinate; MFCD00014823; (2-Aminoethoxy)diphenylborane

Molecular Formula(C6H5)2BOCH2CH2NH2

Molecular Weight225.09

Purity97%

Density1.0±0.1 g/cm3

Boiling Point325.3±34.0 °C at 760 mmHg

Melting Point192-194 °C(lit.)

Flash Point

Appearancepowder

EINECS208-366-5

MSDSChineseEnglish

Symboltransportation

Signal WordWarning

Cat. No.: 2A-9060678 Purity: 97%
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Quality Control of [ 524-95-8 ] Purity: 97% SDS Specification MoL

Chemical & Physical Properties
CAS Number524-95-8
Catalog No.2A-9060678
Chinese Name2-氨基乙基联苯基硼酸酯
Synonyms2-Aminoethoxydiphenylborane; Borinic acid, B,B-diphenyl-, 2-aminoethyl ester; Natural Product Reagent A; 2-diphenylboranyloxyethanamine; 2-Aminoethoxydiphenyl borate,2-APB,2-Aminoethyl diphenyl borate; Diphenylborinic Acid Ethanolamine Ester; EINECS 208-366-5; Diphenylborinic Acid 2-Aminoethyl Ester; 2-Aminoethyldiphenylborinate; 2-Aminoethyl diphenylborinate; MFCD00014823; (2-Aminoethoxy)diphenylborane
Molecular Formula(C6H5)2BOCH2CH2NH2
Molecular Weight225.09
Purity97
Density1.0±0.1 g/cm3
Boiling Point325.3±34.0 °C at 760 mmHg
Melting Point192-194 °C(lit.)
Appearancepowder
Storage ConditionStore in a cool, dry, well-ventilated warehouse. K
Application2-Aminoethyl diphenylborinate (2-APB) is a cell-permeable IP3R inhibitor. 2-Aminoethyl diphenylborinate inhibits store-operated Ca2+ (SOC) channels and activates some TRP channels (V1, V2, and V3).
EINECS208-366-5
HTC2931900090
PubChem ID57654145
MDL NumberMFCD00014823
SMILESNCCOB(c1ccccc1)c2ccccc2
InChI1S/C14H16BNO/c16-11-12-17-15(13-7-3-1-4-8-13)14-9-5-2-6-10-14/h1-10H,11-12,16H2
InChI KeyBLZVCIGGICSWIG-UHFFFAOYSA-N
Beilstein/REAXYS2942273
NACRES CodeNA.22
UNSPSC12352103
Hazard Symbolstransportation
MSDSmsds/60678_1_524_95_8.pdf
Bioactivity2-Aminoethyl diphenylborinate (2-APB) is a cell-permeable inhibitor of IP3R. 2-Aminoethyl diphenylborinate also inhibits the store-operated Ca2+ (SOC) channel and activates some TRP channels (V1, V2 and V3)[1][2][3]. Related Catalog Signaling Pathways >> Membrane Transporter/Ion Channel >> Calcium Channel Signaling Pathways >> Membrane Transporter/Ion Channel >> TRP Channel Research Areas >> Infection References [1]. Ma S, et al. Effect of Wilforine on the Calcium Signaling Pathway in Mythimna separata Walker MyocytesUsing the Calcium Imaging Technique. J Agric Food Chem. 2019 Nov 27. [2]. Boyacı MG, et al. Effects of 2-Aminoethyl Diphenylborinate, a Modulator of Transient Receptor Potential and OraiChannels in Subarachnoid Hemorrhage: An Experimental Study. [3]. Takahashi K, et al. Molecular mechanism of 2-APB-induced Ca²⁺ influx in external acidification in PC12. Exp Cell Res. 2014 May 1;323(2):337-45. Chemical & Physical Properties Density 1.0±0.1 g/cm3 Boiling Point 325.3±34.0 °C at 760 mmHg Melting Point 192-194 °C(lit.) Molecular Formula C14H16BNO Molecular Weight 225.094 Flash Point 150.6±25.7 °C Exact Mass 225.132492 PSA 35.25000 LogP 3.48 Vapour Pressure 0.0±0.7 mmHg at 25°C Index of Refraction 1.560 InChIKey BLZVCIGGICSWIG-UHFFFAOYSA-N SMILES NCCOB(c1ccccc1)c1ccccc1 Storage condition 2-8°C
Use of2-Aminoethyl diphenylborinate (2-APB) is a cell-permeable inhibitor of IP3R. 2-Aminoethyl diphenylborinate also inhibits the store-operated Ca2+ (SOC) channel and activates some TRP channels (V1, V2 and V3)[1][2][3]. Properties Articles72 Name 2-Aminoethyl Diphenylborinate Synonym More Synonyms 2-Aminoethyl Diphenylborinate Biological Activity Description 2-Aminoethyl diphenylborinate (2-APB) is a cell-permeable inhibitor of IP3R. 2-Aminoethyl diphenylborinate also inhibits the store-operated Ca2+ (SOC) channel and activates some TRP channels (V1, V2 and V3)[1][2][3]. Related Catalog Signaling Pathways >> Membrane Transporter/Ion Channel >> Calcium Channel Signaling Pathways >> Membrane Transporter/Ion Channel >> TRP Channel Research Areas >> Infection References [1]. Ma S, et al. Effect of Wilforine on the Calcium Signaling Pathway in Mythimna separata Walker MyocytesUsing the Calcium Imaging Technique. J Agric Food Chem. 2019 Nov 27. [2]. Boyacı MG, et al. Effects of 2-Aminoethyl Diphenylborinate, a Modulator of Transient Receptor Potential and OraiChannels in Subarachnoid Hemorrhage: An Experimental Study. [3]. Takahashi K, et al. Molecular mechanism of 2-APB-induced Ca²⁺ influx in external acidification in PC12. Exp Cell Res. 2014 May 1;323(2):337-45. Chemical & Physical Properties Molecular Formula C14H16BNO Exact Mass 225.132492 PSA 35.25000 Index of Refraction 1.560 InChIKey BLZVCIGGICSWIG-UHFFFAOYSA-N
Tax Rebate13.0%
SupervisionAB (Inbound cargo customs clearance form)
Transport InfoProduct name: Purity: 98.0%
MSDS Transport InfoModule 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available
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