Home > Products > Pharmaceuticals & Life Science > Pharmaceutical Intermediates > (S)-1-[4-[[2-(2-Aminopyrimidin-5-yl)-7-methyl-4-(morpholin-4-yl)thieno[3,2-d]pyrimidin-6-yl]methyl]piperazin-1-yl]-2-hydroxypropan-1-one

(S)-1-[4-[[2-(2-Aminopyrimidin-5-yl)-7-methyl-4-(morpholin-4-yl)thieno[3,2-d]pyrimidin-6-yl]methyl]piperazin-1-yl]-2-hydroxypropan-1-one

Name: (S)-1-[4-[[2-(2-Aminopyrimidin-5-yl)-7-methyl-4-(morpholin-4-yl)thieno[3,2-d]pyrimidin-6-yl]methyl]piperazin-1-yl]-2-hydroxypropan-1-one
Brand: 2A Biotech
SKU: 2A-9060223

CAS Number1032754-93-0

SynonymsGDC 0980; GDC-0980; GNE 390; Apitolisib; GDC0980; RG7422; Apitolisib (GDC-0980)

Molecular FormulaC23H30O3N8S1

Molecular Weight498.61

Density1.4±0.1 g/cm3

Boiling Point718.6±70.0 °C at 760 mmHg

Appearancepowder

MSDSChinese English

Cat. No.: 2A-9060223 Purity:

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Quality Control of [ 1032754-93-0 ] SDS Specification MoL

Chemical & Physical Properties
CAS Number	1032754-93-0
Catalog No.	2A-9060223
Chinese Name	Apitolisib (GDC-0980)
Synonyms	GDC 0980; GDC-0980; GNE 390; Apitolisib; GDC0980; RG7422; Apitolisib (GDC-0980)
Molecular Formula	C23H30O3N8S1
Molecular Weight	498.61
Density	1.4±0.1 g/cm3
Boiling Point	718.6±70.0 °C at 760 mmHg
Appearance	powder
Storage Condition	-20℃
Application	Apitolisib (GDC-0980) is an orally active PI3K and mTOR (TORC1/2) kinase inhibitor that inhibits the activity of PI3Kα/PI3Kβ/PI3Kδ/PI3Kγ with IC50 values of 5 nM/27 nM/7 nM/14 nM. Inhibits mTOR with
MDL Number	MFCD20274520
SMILES	Cc1c(CN2CCN(C(=O)C(C)O)CC2)sc2c(N3CCOCC3)nc(-c3cnc(N)nc3)nc12
InChI Key	YOVVNQKCSKSHKT-HNNXBMFYSA-N
MSDS	msds/60223_1_1032754_93_0.pdf
Transport Info	Product name: GDC-0980(RG7422)

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(S)-1-[4-[[2-(2-Aminopyrimidin-5-yl)-7-methyl-4-(morpholin-4-yl)thieno[3,2-d]pyrimidin-6-yl]methyl]piperazin-1-yl]-2-hydroxypropan-1-one

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