![4-(2-Chlorophenoxy)-N-[3-[(methylamino)carbonyl]phenyl]-1-piperidinecarboxamide structure, CAS 1032229-33-6](/structures/60000/59510_1_1032229_33_6.png)
CAS Number1032229-33-6
Synonyms(4-(2-chlorophenoxy)-N-(3-(methylcarbamoyl)-phenyl)piperidine-1-carboxamide); 4-(2-chlorophenoxy)-N-{3-[(methylamino)carbonyl]phenyl}piperidine-1-carboxamide; 4-(2-Chlorophenoxy)-N-[3-[(methylamino)carbonyl]phenyl]-1-piperidinecarboxamide; A939572
Molecular FormulaC20H22ClN3O3
Molecular Weight387.86
Purity≥98 (HPLC)%
Density1.302 g/cm3
Boiling Point633.5ºC at 760 mmHg
Appearancepowder
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 1032229-33-6 |
| Catalog No. | 2A-9059510 |
| Chinese Name | 4-(2-氯苯氧基)-N-[3-[(甲基氨基)羰基]苯基]-1-哌啶甲酰胺 |
| Synonyms | (4-(2-chlorophenoxy)-N-(3-(methylcarbamoyl)-phenyl)piperidine-1-carboxamide); 4-(2-chlorophenoxy)-N-{3-[(methylamino)carbonyl]phenyl}piperidine-1-carboxamide; 4-(2-Chlorophenoxy)-N-[3-[(methylamino)carbonyl]phenyl]-1-piperidinecarboxamide; A939572 |
| Molecular Formula | C20H22ClN3O3 |
| Molecular Weight | 387.86 |
| Purity | ≥98 (HPLC) |
| Density | 1.302 g/cm3 |
| Boiling Point | 633.5ºC at 760 mmHg |
| Appearance | powder |
| Storage Condition | 2-8℃ |
| Application | A939572 is an orally active SCD1 inhibitor with IC50 of <4 nM and 37 nM for mSCD1 and hSCD1, respectively. |
| HTC | 2933399090 |
| MDL Number | MFCD10698997 |
| SMILES | Clc1c(cccc1)OC2CCN(CC2)C(=O)Nc3cc(ccc3)C(=O)NC |
| InChI | 1S/C20H22ClN3O3/c1-22-19(25)14-5-4-6-15(13-14)23-20(26)24-11-9-16(10-12-24)27-18-8-3-2-7-17(18)21/h2-8,13,16H,9-12H2,1H3,(H,22,25)(H,23,26) |
| InChI Key | DPYTYQFYDLYWHZ-UHFFFAOYSA-N |
| NACRES Code | NA.77 |
| UNSPSC | 12352200 |
| MSDS | msds/59510_1_1032229_33_6.pdf |
| Use of | A939572 is a potent, and orally bioavailable SCD1 inhibitor with IC50 values of <4 nM and 37 nM for mSCD1 and hSCD1, respectively. Properties Name 4-(2-chlorophenoxy)-N-[3-(methylcarbamoyl)phenyl]piperidine-1-carboxamide Synonym More Synonyms A939572 Biological Activity Description A939572 is a potent, and orally bioavailable SCD1 inhibitor with IC50 values of <4 nM and 37 nM for mSCD1 and hSCD1, respectively. Related Catalog Signaling Pathways >> Metabolic Enzyme/Protease >> Stearoyl-CoA Desaturase (SCD) Research Areas >> Cancer IC50: <4 nM (mSCD1), 37 nM (hSCD1)[1] References [1]. Xin Z, et al. Discovery of piperidine-aryl urea-based stearoyl-CoA desaturase 1 inhibitors. Bioorg Med Chem Lett. 2008 Aug 1;18(15):4298-302. [2]. von Roemeling CA, et al. Stearoyl-CoA desaturase 1 is a novel molecular therapeutic target for clear cell renal cell carcinoma. Clin Cancer Res. 2013 May 1;19(9):2368-80. Chemical & Physical Properties Exact Mass 387.13500 PSA 70.67000 LogP 4.17670 InChIKey DPYTYQFYDLYWHZ-UHFFFAOYSA-N Storage condition 2-8℃ Safety Information HS Code 2933399090 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
| Related Products in Heterocyclic Building Blocks | ||
|---|---|---|
| 4-(6,7-Dimethoxy-9H-pyrimido[4,5-b]indol-4-yl)-N-[4-[[(4-fluorophenyl)amino]sulfonyl]phenyl]-1-piperazinecarbothioamide | 1023310-86-2 | 2A-9059499 |
| 3-(4-Fluorophenyl)pyrrolidine hydrochloride | 1029636-03-0 | 2A-9059505 |
| 3-Chloro-5,6,7,8-tetrahydropyrido[3,4-c]pyridazine | 1029721-23-0 | 2A-9059506 |
| 5-Bromo-3,7-dimethyl-1H-indazole | 1031417-71-6 | 2A-9059507 |
| 3,4-Dihydro-6-methyl-3-(2-methylpropyl)-4-oxofuro[2,3-d]pyrimidine-5-carboxylic acid | 1031967-08-4 | 2A-9059509 |
| Ethyl 7-bromobenzofuran-2-carboxylate | 1033201-65-8 | 2A-9059514 |
| 3-(4-Bromophenyl)-5-(1-chloro-2-methylpropan-2-yl)-1,2,4-oxadiazole | 1033201-95-4 | 2A-9059515 |
| 3-(3-Bromophenyl)-1,2,4-oxadiazole | 1033202-12-8 | 2A-9059517 |
| Poly[[4,4-bis(2-ethylhexyl)-4H-cyclopenta[2,1-b:3,4-b']dithiophene-2,6-diyl]-2,5-thiophenediyl-2,1,3-benzothiadiazole-4,7-diyl-2,5-thiophenediyl] | 1035681-83-4 | 2A-9059520 |
| a-Methyltryptamine (3-(2-Methylaminoethyl)indole) | 299-26-3 | 2A-9059560 |
| Browse all Heterocyclic Building Blocks products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA
EN
SDS