![N-(1,1-Dimethylethyl)-3-[[5-methyl-2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]amino]benzenesulfonamide structure, CAS 936091-14-4](/structures/60000/59232_1_936091_14_4.png)
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 936091-14-4 |
| Catalog No. | 2A-9059232 |
| Chinese Name | N-(1,1-二甲基乙基)-3-[[5-甲基-2-[[4-(4-甲基-1-哌嗪基)苯基]氨基]-4-嘧啶基]氨基]苯磺酰胺 |
| Synonyms | Kinome_702; TG101209 |
| Molecular Formula | C26H35O2N7S1 |
| Molecular Weight | 509.68 |
| Purity | 98.00 |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 703.1±70.0 °C at 760 mmHg |
| Appearance | White to gray solid |
| Storage Condition | -20℃ |
| Application | TG101209 is a selective and potent JAK2 inhibitor with an IC50 value of 6 nM; it can also inhibit the activity of Flt3 and RET with an IC50 value of 25 nM and 17 nM respectively. |
| MDL Number | MFCD15528085 |
| SMILES | Cc1cnc(Nc2ccc(N3CCN(C)CC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 |
| InChI Key | JVDOKQYTTYUYDV-UHFFFAOYSA-N |
| MSDS | msds/59232_1_936091_14_4.pdf |
| Transport Info | Product name: TG101209 |
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