![N-[3-[(5-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide structure, CAS 918505-84-7](/structures/60000/59142_1_918505_84_7.png)
CAS Number918505-84-7
SynonymsPLX 4720,PLX-4720; N-{3-[(5-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl}-1-propanesulfonamide; PLX-4720; S1152_Selleck; PLX4720
Molecular FormulaC17H14O3N3Cl1S1F2
Molecular Weight413.83
Purity98.00%
Density1.5±0.1 g/cm3
Boiling Point621.4±65.0 °C at 760 mmHg
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 918505-84-7 |
| Catalog No. | 2A-9059142 |
| Chinese Name | PLX-4720 |
| Synonyms | PLX 4720,PLX-4720; N-{3-[(5-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl}-1-propanesulfonamide; PLX-4720; S1152_Selleck; PLX4720 |
| Molecular Formula | C17H14O3N3Cl1S1F2 |
| Molecular Weight | 413.83 |
| Purity | 98.00 |
| Density | 1.5±0.1 g/cm3 |
| Boiling Point | 621.4±65.0 °C at 760 mmHg |
| Storage Condition | -20°C |
| Application | PLX-4720 is a potent, selective inhibitor of B-RafV600E with an IC50 value of 13 nM; the same selectivity for c-Raf-1 and 10-fold selectivity over wild-type B-Raf. |
| MDL Number | MFCD14635203 |
| SMILES | CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2c[nH]c3ncc(Cl)cc23)c1F |
| InChI Key | YZDJQTHVDDOVHR-UHFFFAOYSA-N |
| MSDS | msds/59142_1_918505_84_7.pdf |
| Transport Info | Product name: PLX-4720 |
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