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NVP-BEZ 235 structure, CAS 915019-65-7

NVP-BEZ 235

CAS Number915019-65-7

SynonymsNVPBEZ235; S1009_Selleck; BEZ235; NVP-BEZ235; NVP-BEZ 235; Dactolisib; 2-methyl-2-[4-(3-methyl-2-oxo-8-quinolin-3-ylimidazo[4,5-c]quinolin-1-yl)phenyl]propanenitrile; NVP BEZ235; BEZ-235; NVP-BEZ235-NX

Molecular FormulaC30H23O1N5

Molecular Weight469.55

Purity98.00%

Density1.3±0.1 g/cm3

Boiling Point701.0±70.0 °C at 760 mmHg

Melting Point288-289°C

Flash Point

Appearance

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Cat. No.: 2A-9059106 Purity: 98.00%
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Quality Control of [ 915019-65-7 ] Purity: 98.00% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number915019-65-7
Catalog No.2A-9059106
Chinese NameDactolisib (BEZ235)
SynonymsNVPBEZ235; S1009_Selleck; BEZ235; NVP-BEZ235; NVP-BEZ 235; Dactolisib; 2-methyl-2-[4-(3-methyl-2-oxo-8-quinolin-3-ylimidazo[4,5-c]quinolin-1-yl)phenyl]propanenitrile; NVP BEZ235; BEZ-235; NVP-BEZ235-NX
Molecular FormulaC30H23O1N5
Molecular Weight469.55
Purity98.00
Density1.3±0.1 g/cm3
Boiling Point701.0±70.0 °C at 760 mmHg
Melting Point288-289°C
Storage ConditionRefrigerator
ApplicationBEZ235 is a dual pan-class I PI3K and mTOR inhibitor, acting on p110α/γ/δ/β and mTOR, with IC50 of 4 nM/5 nM/7 nM/75 nM and 20.7 nM, respectively. BEZ235 inhibits mTORC1 and mTORC2.
MDL NumberMFCD10565944
SMILESCn1c(=O)n(-c2ccc(C(C)(C)C#N)cc2)c2c3cc(-c4cnc5ccccc5c4)ccc3ncc21
InChI KeyJOGKUKXHTYWRGZ-UHFFFAOYSA-N
MSDSmsds/59106_1_915019_65_7.pdf
Transport InfoProduct name: BEZ235
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