![4-Methyl-3-[[3-[2-(methylamino)-4-pyrimidinyl]-2-pyridinyl]oxy]-N-[3-(trifluoromethyl)phenyl]benzamide structure, CAS 870223-96-4](/structures/60000/58616_1_870223_96_4.png)
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 870223-96-4 |
| Catalog No. | 2A-9058616 |
| Chinese Name | 4-甲基-3-[[3-[2-(甲基氨基)-4-嘧啶基]-2-吡啶基]氧基]-N-[3-(三氟甲基)苯基]苯甲酰胺 |
| Synonyms | 4-methyl-3-(3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-yloxy)-N-(3-(trifluoromethyl)phenyl)benzamide; AMG-Tie2; pyridylpyrimidine ether 4; AMG-Tie2-1 |
| Molecular Formula | C25H20O2N5F3 |
| Molecular Weight | 479.46 |
| Purity | 98.00 |
| Density | 1.4±0.1 g/cm3 |
| Application | AMG-Tie2-1 is an inhibitor of endothelial cell kinase 2 (Tie2) and VEGF receptor 2 (VEGFR2), with IC50 values of 1 and 3nm respectively. |
| MDL Number | MFCD16038641 |
| SMILES | CNc1nccc(-c2cccnc2Oc2cc(C(=O)Nc3cccc(C(F)(F)F)c3)ccc2C)n1 |
| InChI Key | ZVIWALRWYYSHSU-UHFFFAOYSA-N |
| MSDS | msds/58616_1_870223_96_4.pdf |
| Transport Info | Product name: AMG-Tie2-1 |
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