| Chemical & Physical Properties | |
|---|---|
| CAS Number | 796967-16-3 |
| Catalog No. | 2A-9058213 |
| Chinese Name | 利尼伐尼 |
| Synonyms | Linifanib; S1003_Selleck; Kinome_532; ABT 869; ABT-869 |
| Molecular Formula | C21H18O1N5F1 |
| Molecular Weight | 375.41 |
| Purity | 98.00 |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 542.2±50.0 °C at 760 mmHg |
| Melting Point | 180-183ºC (dec.) |
| Storage Condition | -20?C Freezer |
| Application | Linifanib (ABT-869) is a multi-target inhibitor of the VEGF and PDGFR receptor families. The IC50 values for inhibiting KDR, Flt-1, PDGFRβ and FLT3 are 3, 4, 66 and 4 nM respectively. |
| MDL Number | MFCD11840918 |
| SMILES | Cc1ccc(F)c(NC(=O)Nc2ccc(-c3cccc4[nH]nc(N)c34)cc2)c1 |
| InChI Key | MPVGZUGXCQEXTM-UHFFFAOYSA-N |
| MSDS | msds/58213_1_796967_16_3.pdf |
| Transport Info | Product name: Linifanib (ABT-869) |
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