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Home > Products > Pharmaceutical R&D Materials > Heterocyclic Building Blocks > N-[4-[(6,7-Dimethoxy-4-quinolinyl)oxy]-2-methoxyphenyl]-N'-[1-(2-thiazolyl)ethyl]urea
N-[4-[(6,7-Dimethoxy-4-quinolinyl)oxy]-2-methoxyphenyl]-N'-[1-(2-thiazolyl)ethyl]urea structure, CAS 623142-96-1

N-[4-[(6,7-Dimethoxy-4-quinolinyl)oxy]-2-methoxyphenyl]-N'-[1-(2-thiazolyl)ethyl]urea

CAS Number623142-96-1

Synonyms1-{4-[(6,7-Dimethoxy-4-quinolinyl)oxy]-2-methoxyphenyl}-3-[1-(1,3-thiazol-2-yl)ethyl]urea; hms3244k11; hms3244k12; N-(4-((6,7-dimethoxy-4-quinolyl)oxy)-2-methoxyphenyl)-N'-(1-(1,3-thiazole-2-yl)ethyl)urea; Ki20227

Molecular FormulaC24H24N4O5S

Molecular Weight480.54

Purity98.00%

Density1.3±0.1 g/cm3

Boiling Point621.8±55.0 °C at 760 mmHg

Melting Point

Flash Point

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Cat. No.: 2A-9057725 Purity: 98.00%
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Quality Control of [ 623142-96-1 ] Purity: 98.00% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number623142-96-1
Catalog No.2A-9057725
Chinese NameN-[4-[(6,7-二甲氧基-4-喹啉基)氧基]-2-甲氧基苯基]-N'-[1-(2-噻唑基)乙基]脲
Synonyms1-{4-[(6,7-Dimethoxy-4-quinolinyl)oxy]-2-methoxyphenyl}-3-[1-(1,3-thiazol-2-yl)ethyl]urea; hms3244k11; hms3244k12; N-(4-((6,7-dimethoxy-4-quinolyl)oxy)-2-methoxyphenyl)-N'-(1-(1,3-thiazole-2-yl)ethyl)urea; Ki20227
Molecular FormulaC24H24N4O5S
Molecular Weight480.54
Purity98.00
Density1.3±0.1 g/cm3
Boiling Point621.8±55.0 °C at 760 mmHg
Storage Condition2-8℃
ApplicationKi-20227 is a CSF1R inhibitor with an IC50 of 2 nM, an IC50 of 12 nM for VEGFR2, and an IC50 of 451/217 nM for c-Kit/PDGFRβ.
MDL NumberC24H24N4O5S
SMILESCOc1cc(Oc2ccnc3cc(OC)c(OC)cc23)ccc1NC(=O)NC(C)c1nccs1
InChI KeySHPFDGWALWEPGS-UHFFFAOYSA-N
MSDSmsds/57725_1_623142_96_1.pdf
Transport InfoProduct name: Ki20227
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