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6-[5-(Cyclopropylcarbamoyl)-3-fluoro-2-methylphenyl]-N-(2,2-dimethylpropyl)pyridine-3-carboxamide

Name: 6-[5-(Cyclopropylcarbamoyl)-3-fluoro-2-methylphenyl]-N-(2,2-dimethylpropyl)pyridine-3-carboxamide
Brand: 2A Biotech
SKU: 2A-9057633

CAS Number585543-15-3

SynonymsUNII-F2DQF16BXE; 6-[5-(Cyclopropylcarbamoyl)-3-fluoro-2-methylphenyl]-N-(2,2-dimethylpropyl)nicotinamide; Losmapimod

Molecular FormulaC22H26FN3O2

Molecular Weight383.46

Purity≥98 (HPLC)%

Density1.2±0.1 g/cm3

Boiling Point529.4±50.0 °C at 760 mmHg

Appearancepowder

Cat. No.: 2A-9057633 Purity: ≥98 (HPLC)%

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Quality Control of [ 585543-15-3 ] Purity: ≥98 (HPLC)% SDS Specification MoL

Chemical & Physical Properties
CAS Number	585543-15-3
Catalog No.	2A-9057633
Chinese Name	6-[5-(环丙基氨基甲酰基)-3-氟-2-甲基苯基]-N-(2,2-二甲基丙基)吡啶-3-甲酰胺
Synonyms	UNII-F2DQF16BXE; 6-[5-(Cyclopropylcarbamoyl)-3-fluoro-2-methylphenyl]-N-(2,2-dimethylpropyl)nicotinamide; Losmapimod
Molecular Formula	C22H26FN3O2
Molecular Weight	383.46
Purity	≥98 (HPLC)
Density	1.2±0.1 g/cm3
Boiling Point	529.4±50.0 °C at 760 mmHg
Appearance	powder
Storage Condition	-20℃
Application	Losmapimod is a potent, selective, orally available p38 MAPK inhibitor with pKi values of 8.1 and 7.6 for p38α and p38β, respectively.
MDL Number	MFCD16619322
SMILES	O=C(NCC(C)(C)C)C1=CC=C(C2=C(C)C(F)=CC(C(NC3CC3)=O)=C2)N=C1
InChI	1S/C22H26FN3O2/c1-13-17(9-15(10-18(13)23)21(28)26-16-6-7-16)19-8-5-14(11-24-19)20(27)25-12-22(2,3)4/h5,8-11,16H,6-7,12H2,1-4H3,(H,25,27)(H,26,28)
InChI Key	KKYABQBFGDZVNQ-UHFFFAOYSA-N
NACRES Code	NA.77
UNSPSC	12352200
MSDS	msds/57633_1_585543_15_3.pdf
Transport Info	Product Name: Losmapimod

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