CAS Number519055-62-0
SynonymsN-[(5-Bromo-2-thienyl)sulfonyl]-2,4-dichlorobenzamide; 5-Bromo-N-(2,4-dichlorobenzoyl)-2-thiophenesulfonamide; Tasisulam; cc-591; T5SJ BSWMVR BG DG&& EE; LY573636
Molecular FormulaC11H6BrCl2NO3S2
Molecular Weight415.11
Purity≥98 (HPLC)%
Density1.8±0.1 g/cm3
Appearancepowder
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 519055-62-0 |
| Catalog No. | 2A-9057555 |
| Chinese Name | 他斯索兰 |
| Synonyms | N-[(5-Bromo-2-thienyl)sulfonyl]-2,4-dichlorobenzamide; 5-Bromo-N-(2,4-dichlorobenzoyl)-2-thiophenesulfonamide; Tasisulam; cc-591; T5SJ BSWMVR BG DG&& EE; LY573636 |
| Molecular Formula | C11H6BrCl2NO3S2 |
| Molecular Weight | 415.11 |
| Purity | ≥98 (HPLC) |
| Density | 1.8±0.1 g/cm3 |
| Appearance | powder |
| Storage Condition | -20℃ |
| Application | Tasisulam is a small molecule antineoplastic drug that inhibits mitotic progression and induces vascular normalization. Tasisulam induces apoptosis through the intrinsic pathway. |
| HTC | 2934999090 |
| MDL Number | MFCD11973637 |
| SMILES | [S](=O)(=O)(NC(=O)c2c(cc(cc2)Cl)Cl)c1[s]c(cc1)Br |
| InChI | 1S/C11H6BrCl2NO3S2/c12-9-3-4-10(19-9)20(17,18)15-11(16)7-2-1-6(13)5-8(7)14/h1-5H,(H,15,16) |
| InChI Key | WWONFUQGBVOKOF-UHFFFAOYSA-N |
| NACRES Code | NA.77 |
| UNSPSC | 12352200 |
| MSDS | msds/57555_1_519055_62_0.pdf |
| Use of | Tasisulam is a small molecule antitumor agent that inhibits mitotic progression and induces vascular normalization. Tasisulam induces apoptosis via the intrinsic pathway[1]. Properties Name N-(5-bromothiophen-2-yl)sulfonyl-2,4-dichlorobenzamide Synonym More Synonyms Tasisulam Biological Activity Description Tasisulam is a small molecule antitumor agent that inhibits mitotic progression and induces vascular normalization. Tasisulam induces apoptosis via the intrinsic pathway[1]. Related Catalog Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer References [1]. Meier T, et al. Tasisulam sodium, an antitumor agent that inhibits mitotic progression and induces vascular normalization. Mol Cancer Ther. 2011 Nov;10(11):2168-78. Chemical & Physical Properties Molecular Formula C11H6BrCl2NO3S2 Exact Mass 412.834930 PSA 99.86000 Index of Refraction 1.657 InChIKey WWONFUQGBVOKOF-UHFFFAOYSA-N Storage condition -20℃ Safety Information HS Code 2934999090 Synthetic Route Total: 1 Page 2,4-Dichloroben... CAS#:50-84-0 5-bromothiophen... CAS#:1152981-12-8 CAS#:519055-62-0 Literature: Kosal, Andrew D.; Wilson, Erin E.; Ashfeld, Brandon L. Chemistry--A European Journal, 2012 , vol. 18, # 45 p. 14444 - 14453,10 Title/Abstract Full Text Show Details Kosal, Andrew D.; Wilson, Erin E.; Ashfeld, Brandon L. Chemistry - A European Journal, 2012 , vol. 18, # 45 p. 14444 - 14453 2-Bromothiophen... CAS#:53595-65-6 2,4-Dichloroben... CAS#:89-75-8 CAS#:519055-62-0 Literature: Yates, Matthew H.; Kallman, Neil J.; Ley, Christopher P.; Wei, Jeffrey N. Organic Process Research and Development, 2009 , vol. 13, # 2 p. 255 - 262 2-Bromothiophen... CAS#:53595-65-6 2,4-Dichloroben... CAS#:50-84-0 CAS#:519055-62-0 Literature: Mader, Mary M.; Shih, Chuan; Considine, Eileen; De Dios, Alfonso; Grossman, Cora Sue; Hipskind, Philip A.; Lin, Ho-Shen; Lobb, Karen L.; Lopez, Beatriz; Lopez, Jose E.; Cabrejas, Luisa M. Martin; Richett, Michael E.; White, Wesley T.; Cheung, Yiu-Yin; Huang, Zhongping; Reilly, John E.; Dinn, Sean R. Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 3 p. 617 - 620 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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