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Motesanib

Name: Motesanib
Brand: 2A Biotech
SKU: 2A-9057267

CAS Number453562-69-1

SynonymsMotesanib; N-(3,3-Dimethyl-2,3-dihydro-1H-indol-6-yl)-2-[(pyridin-4-ylmethyl)amino]nicotinamide; N-(3,3-Dimethyl-2,3-dihydro-1H-indol-6-yl)-2-[(4-pyridinylmethyl)amino]nicotinamide; N-(3,3-dimethylindolin-6-yl)-2-(pyridin-4-ylmethylamino)nicotinamide; Motesanib Base

Molecular FormulaC22H23O1N5

Molecular Weight373.46

Purity98.00%

Density1.3±0.1 g/cm3

Boiling Point517.3±50.0 °C at 760 mmHg

MSDSChinese English

Cat. No.: 2A-9057267 Purity: 98.00%

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Quality Control of [ 453562-69-1 ] Purity: 98.00% SDS Specification MoL

Chemical & Physical Properties
CAS Number	453562-69-1
Catalog No.	2A-9057267
Chinese Name	莫特塞尼
Synonyms	Motesanib; N-(3,3-Dimethyl-2,3-dihydro-1H-indol-6-yl)-2-[(pyridin-4-ylmethyl)amino]nicotinamide; N-(3,3-Dimethyl-2,3-dihydro-1H-indol-6-yl)-2-[(4-pyridinylmethyl)amino]nicotinamide; N-(3,3-dimethylindolin-6-yl)-2-(pyridin-4-ylmethylamino)nicotinamide; Motesanib Base
Molecular Formula	C22H23O1N5
Molecular Weight	373.46
Purity	98.00
Density	1.3±0.1 g/cm3
Boiling Point	517.3±50.0 °C at 760 mmHg
Storage Condition	-20°C
Application	Motesanib is a potent ATP competitive inhibitor of VEGFR1/2/3 with IC50 values of 2 nM/3 nM/6 nM. It is similar to Kit in selectivity and is more than 10 times more selective than PDGFR and Ret.
MDL Number	MFCD10567689
SMILES	CC1(C)CNc2cc(NC(=O)c3cccnc3NCc3ccncc3)ccc21
InChI	InChI=1S/C22H23N5O/c1-22(2)14-26-19-12-16(5-6-18(19)22)27-21(28)17-4-3-9-24-20(17)25-13-15-7-10-23-11-8-15/h3-12,26H,13-14H2,1-2H3,(H,24,25)(H,27,28)
InChI Key	RAHBGWKEPAQNFF-UHFFFAOYSA-N
MSDS	msds/57267_1_453562_69_1.pdf
Transport Info	Product Name: Motesanib

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Motesanib

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