EN
0
Home > Products > Specialty & Industrial Chemicals > Specialty Chemicals > Canertinib
Canertinib structure, CAS 267243-28-7

Canertinib

CAS Number267243-28-7

SynonymsN-{4-[(3-chloro-4-fluorophenyl)amino]-7-[3-(morpholin-4-yl)propoxy]quinazolin-6-yl}prop-2-enamide; Canertinib (CI-1033); UNII-C78W1K5ASF; N-(4-(3-chloro-4-fluorophenylamino)-7-(3-morpholinopropoxy)quinazolin-6-yl)acrylamide; N-{4-[(3-Chloro-4-fluorophenyl)amino]-7-[3-(4-morpholinyl)propoxy]-6-quinazolinyl}acrylamide; Canertinib; S1019_Selleck; N-[4-(3-chloro-4-fluoroanilino)-7-(3-morpholin-4-ylpropoxy)quinazolin-6-yl]prop-2-enamide; N-{4-[(3-Chloro-4-fluorophenyl)amino]-7-[3-(morpholin-4-yl)propoxy]quinazolin-6-yl}acrylamide; CI-1033

Molecular FormulaC24H25ClFN5O3

Molecular Weight485.95

Purity98.00%

Density1.4±0.1 g/cm3

Boiling Point691.0±55.0 °C at 760 mmHg

Melting Point188-190°

Flash Point

AppearanceWhite or similar to white crystalline powder

EINECS

MSDSChineseEnglish

Symbol

Signal Word

Cat. No.: 2A-9056171 Purity: 98.00%
Change View

Please Login or Create an Account to: See VlP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

Inquiry

Quality Control of [ 267243-28-7 ] Purity: 98.00% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number267243-28-7
Catalog No.2A-9056171
Chinese Name卡奈替尼
SynonymsN-{4-[(3-chloro-4-fluorophenyl)amino]-7-[3-(morpholin-4-yl)propoxy]quinazolin-6-yl}prop-2-enamide; Canertinib (CI-1033); UNII-C78W1K5ASF; N-(4-(3-chloro-4-fluorophenylamino)-7-(3-morpholinopropoxy)quinazolin-6-yl)acrylamide; N-{4-[(3-Chloro-4-fluorophenyl)amino]-7-[3-(4-morpholinyl)propoxy]-6-quinazolinyl}acrylamide; Canertinib; S1019_Selleck; N-[4-(3-chloro-4-fluoroanilino)-7-(3-morpholin-4-ylpropoxy)quinazolin-6-yl]prop-2-enamide; N-{4-[(3-Chloro-4-fluorophenyl)amino]-7-[3-(morpholin-4-yl)propoxy]quinazolin-6-yl}acrylamide; CI-1033
Molecular FormulaC24H25ClFN5O3
Molecular Weight485.95
Purity98.00
Density1.4±0.1 g/cm3
Boiling Point691.0±55.0 °C at 760 mmHg
Melting Point188-190°
AppearanceWhite or similar to white crystalline powder
Storage Condition-20°C
ApplicationCanertinib (CI-1033; PD-183805) is a potent, irreversible EGFR inhibitor; inhibiting cellular EGFR and ErbB2 autophosphorylation with IC50 values ​​of 7.4 and 9 nM, respectively.
MDL NumberC24H25ClFN5O3
SMILESC=CC(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OCCCN1CCOCC1
InChIInChI=1S/C24H25ClFN5O3/c1-2-23(32)30-21-13-17-20(14-22(21)34-9-3-6-31-7-10-33-11-8-31)27-15-28-24(17)29-16-4-5-19(26)18(25)12-16/h2,4-5,12-15H,1,3,6-11H2,(H,30,32)(H,27,28,29)
InChI KeyOMZCMEYTWSXEPZ-UHFFFAOYSA-N
MSDSmsds/56171_1_267243_28_7.pdf
Transport InfoProduct name: Canertinib (CI-1033)
Related Products in Specialty Chemicals
N,N,N',N'-Tetramethyl-O-(N-succinimidyl)uronium hexafluorophosphate265651-18-12A-9056161
2,3-Difluoro-D-phenylalanine266360-59-22A-9056164
2,5-Difluoro-D-phenylalanine266360-61-62A-9056166
2-Amino-4,6-dimethoxy-5-pyrimidinol267224-18-02A-9056168
D-2-Bromophenylalanine267225-27-42A-9056169
L-Styrylalanine267650-37-32A-9056172
Udenafil268203-93-62A-9056173
Ethyl 2-amino-5-iodobenzoate268568-11-22A-9056176
Methyl 4-cyano-3-fluorobenzoate268734-34-52A-9056181
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-aspartic acid 4-[[4-[[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino]phenyl]methyl] ester269066-08-22A-9056183
Browse all Specialty Chemicals products »
Contact Us

Phone:

630-322-8886

630-322-8887

Email:

[email protected]

Office Locations:

Chicago, IL, USA

San Francisco, CA, USA