![6-(2,6-Dichlorophenyl)-8-methyl-2-[[3-(methylthio)phenyl]amino]pyrido[2,3-d]pyrimidin-7(8H)-one structure, CAS 260415-63-2](/structures/60000/56103_1_260415_63_2.png)
CAS Number260415-63-2
Synonyms6-(2,6-Dichlorophenyl)-8-methyl-2-{[3-(methylsulfanyl)phenyl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one; 6-(2,6-dichlorophenyl)-8-methyl-2-{[3-(methylthio)phenyl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one; 6-(2,6-DICHLORO-PHENYL)-8-METHYL-2-(3-METHYLSULFANYL-PHENYLAMINO)-8H-PYRIDO[2,3-D]PYRIMIDIN-7-ONE; PD173955
Molecular FormulaC21H16Cl2N4OS
Molecular Weight443.35
Purity≥98 (HPLC)%
Density1.5±0.1 g/cm3
Boiling Point626.7±65.0 °C at 760 mmHg
Appearancepowder
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 260415-63-2 |
| Catalog No. | 2A-9056103 |
| Chinese Name | PD173955 |
| Synonyms | 6-(2,6-Dichlorophenyl)-8-methyl-2-{[3-(methylsulfanyl)phenyl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one; 6-(2,6-dichlorophenyl)-8-methyl-2-{[3-(methylthio)phenyl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one; 6-(2,6-DICHLORO-PHENYL)-8-METHYL-2-(3-METHYLSULFANYL-PHENYLAMINO)-8H-PYRIDO[2,3-D]PYRIMIDIN-7-ONE; PD173955 |
| Molecular Formula | C21H16Cl2N4OS |
| Molecular Weight | 443.35 |
| Purity | ≥98 (HPLC) |
| Density | 1.5±0.1 g/cm3 |
| Boiling Point | 626.7±65.0 °C at 760 mmHg |
| Appearance | powder |
| Storage Condition | -20℃ |
| Application | PD173955 is a selective inhibitor of the Src kinase family. The IC50 value for Src, Yes and Abl kinases is about 22nM. It has weak inhibitory effect on FGFR_alpha_ and has no activity on InsR and PKC. |
| MDL Number | MFCD16038305 |
| SMILES | S(C)c1cc(ccc1)Nc2nc3c(cn2)C=C(C(=O)N3C)c4c(cccc4Cl)Cl |
| InChI | 1S/C21H16Cl2N4OS/c1-27-19-12(9-15(20(27)28)18-16(22)7-4-8-17(18)23)11-24-21(26-19)25-13-5-3-6-14(10-13)29-2/h3-11H,1-2H3,(H,24,25,26) |
| InChI Key | VAARYSWULJUGST-UHFFFAOYSA-N |
| NACRES Code | NA.25 |
| UNSPSC | 12352200 |
| MSDS | msds/56103_1_260415_63_2.pdf |
| Transport Info | Product name: PD173955 |
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