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6-(2,6-Dichlorophenyl)-8-methyl-2-[[3-(methylthio)phenyl]amino]pyrido[2,3-d]pyrimidin-7(8H)-one structure, CAS 260415-63-2

6-(2,6-Dichlorophenyl)-8-methyl-2-[[3-(methylthio)phenyl]amino]pyrido[2,3-d]pyrimidin-7(8H)-one

CAS Number260415-63-2

Synonyms6-(2,6-Dichlorophenyl)-8-methyl-2-{[3-(methylsulfanyl)phenyl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one; 6-(2,6-dichlorophenyl)-8-methyl-2-{[3-(methylthio)phenyl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one; 6-(2,6-DICHLORO-PHENYL)-8-METHYL-2-(3-METHYLSULFANYL-PHENYLAMINO)-8H-PYRIDO[2,3-D]PYRIMIDIN-7-ONE; PD173955

Molecular FormulaC21H16Cl2N4OS

Molecular Weight443.35

Purity≥98 (HPLC)%

Density1.5±0.1 g/cm3

Boiling Point626.7±65.0 °C at 760 mmHg

Melting Point

Flash Point

Appearancepowder

EINECS

MSDSChineseEnglish

Symbol

Signal Word

Cat. No.: 2A-9056103 Purity: ≥98 (HPLC)%
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Quality Control of [ 260415-63-2 ] Purity: ≥98 (HPLC)% SDS Specification MoL

Chemical & Physical Properties
CAS Number260415-63-2
Catalog No.2A-9056103
Chinese NamePD173955
Synonyms6-(2,6-Dichlorophenyl)-8-methyl-2-{[3-(methylsulfanyl)phenyl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one; 6-(2,6-dichlorophenyl)-8-methyl-2-{[3-(methylthio)phenyl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one; 6-(2,6-DICHLORO-PHENYL)-8-METHYL-2-(3-METHYLSULFANYL-PHENYLAMINO)-8H-PYRIDO[2,3-D]PYRIMIDIN-7-ONE; PD173955
Molecular FormulaC21H16Cl2N4OS
Molecular Weight443.35
Purity≥98 (HPLC)
Density1.5±0.1 g/cm3
Boiling Point626.7±65.0 °C at 760 mmHg
Appearancepowder
Storage Condition-20℃
ApplicationPD173955 is a selective inhibitor of the Src kinase family. The IC50 value for Src, Yes and Abl kinases is about 22nM. It has weak inhibitory effect on FGFR_alpha_ and has no activity on InsR and PKC.
MDL NumberMFCD16038305
SMILESS(C)c1cc(ccc1)Nc2nc3c(cn2)C=C(C(=O)N3C)c4c(cccc4Cl)Cl
InChI1S/C21H16Cl2N4OS/c1-27-19-12(9-15(20(27)28)18-16(22)7-4-8-17(18)23)11-24-21(26-19)25-13-5-3-6-14(10-13)29-2/h3-11H,1-2H3,(H,24,25,26)
InChI KeyVAARYSWULJUGST-UHFFFAOYSA-N
NACRES CodeNA.25
UNSPSC12352200
MSDSmsds/56103_1_260415_63_2.pdf
Transport InfoProduct name: PD173955
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