![9-[(R)-2-(Phosphonomethoxy)propyl]adenine monohydrate structure, CAS 206184-49-8](/structures/60000/55371_1_206184_49_8.png)
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 206184-49-8 |
| Catalog No. | 2A-9055371 |
| Chinese Name | 9-[(R)-2-(磷酰甲氧基)丙基]腺嘌呤 |
| Synonyms | Tenofovir Monohydrate; Unii-99yxe507il; 9-[(R)-2-(Phosphonomethoxy)propyl]adenine monohydrate; Tenofovir hydrate; Tenofovir (hydrate) |
| Molecular Formula | C9H16N5O5P |
| Molecular Weight | 305.23 |
| Purity | 98.00 |
| Density | 1.79g/cm3 |
| Boiling Point | 616.1ºC at 760mmHg |
| Storage Condition | 2-8℃ |
| Application | Tenofovir hydrate is a nucleotide reverse transcriptase inhibitor used to treat HIV and chronic hepatitis B. |
| HTC | 2933990090 |
| MDL Number | MFCD11519982 |
| SMILES | [P](=O)(O)(O)CO[C@@H](C[n]1c2ncnc(c2nc1)N)C.O |
| InChI | 1S/C9H14N5O4P.H2O/c1-6(18-5-19(15,16)17)2-14-4-13-7-8(10)11-3-12-9(7)14;/h3-4,6H,2,5H2,1H3,(H2,10,11,12)(H2,15,16,17);1H2/t6-;/m1./s1 |
| InChI Key | PINIEAOMWQJGBW-FYZOBXCZSA-N |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| MSDS | msds/55371_1_206184_49_8.pdf |
| Use of | Tenofovir hydrate is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B. Properties Name tenofovir hydrate Synonym More Synonyms Tenofovir Monohydrate Biological Activity Description Tenofovir hydrate is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B. Related Catalog Signaling Pathways >> Anti-infection >> HIV Signaling Pathways >> Anti-infection >> Reverse Transcriptase Research Areas >> Infection References [2]. Musumeci G, et al. M48U1 and Tenofovir combination synergistically inhibits HIV infection in activated PBMCs and human cervicovaginal histocultures. Sci Rep. 2017 Feb 1;7:41018. [3]. Wahl A, et al. Predicting HIV Pre-exposure Prophylaxis Efficacy for Women using a Preclinical Pharmacokinetic-Pharmacodynamic In Vivo Model. Sci Rep. 2017 Feb 1;7:41098. [4]. Menne S, Cote PJ, Korba BE, Antiviral effect of oral administration of tenofovir disoproxil fumarate in woodchucks with chronic woodchuck hepatitis virus infection. Antimicrob Agents Chemother. 2005 Jul;49(7):2720-8. Chemical & Physical Properties Molecular Formula C9H16N5O5P Exact Mass 305.08900 PSA 155.42000 LogP 0.46570 InChIKey PINIEAOMWQJGBW-FYZOBXCZSA-N Storage condition 2-8℃ Safety Information Signal Word Danger Hazard Statements H301 Precautionary Statements Missing Phrase - N15.00950417 RIDADR NONH for all modes of transport HS Code 2933990090 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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