CAS Number130800-90-7
Synonyms2-(4-Methyl-1-piperazinyl)-5-(2,3,5-trichlorophenyl)-4-pyrimidinamine; Sipatrigine [INN:BAN]; 4-Amino-2-(4-methyl-1-piperazinyl)-5-(2,3,5-trichlorophenyl)pyrimidine; Sipatrigine
Molecular FormulaC15H16N5Cl3
Molecular Weight372.68
Purity98.00%
Density1.419 g/cm3
Boiling Point531.1ºC at 760 mmHg
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 130800-90-7 |
| Catalog No. | 2A-9052069 |
| Chinese Name | 西帕曲近 |
| Synonyms | 2-(4-Methyl-1-piperazinyl)-5-(2,3,5-trichlorophenyl)-4-pyrimidinamine; Sipatrigine [INN:BAN]; 4-Amino-2-(4-methyl-1-piperazinyl)-5-(2,3,5-trichlorophenyl)pyrimidine; Sipatrigine |
| Molecular Formula | C15H16N5Cl3 |
| Molecular Weight | 372.68 |
| Purity | 98.00 |
| Density | 1.419 g/cm3 |
| Boiling Point | 531.1ºC at 760 mmHg |
| Storage Condition | 2-8°C, dry, sealed |
| Application | Sipatrigine is a neuroprotective agent, a glutamate release inhibitor, a voltage-dependent sodium channel and calcium channel inhibitor that can penetrate the central nervous system. It has the potent |
| HTC | 2933990090 |
| MDL Number | MFCD00867772 |
| SMILES | CN1CCN(c2ncc(-c3cc(Cl)cc(Cl)c3Cl)c(N)n2)CC1 |
| InChI | InChI=1S/C15H16Cl3N5/c1-22-2-4-23(5-3-22)15-20-8-11(14(19)21-15)10-6-9(16)7-12(17)13(10)18/h6-8H,2-5H2,1H3,(H2,19,20,21) |
| InChI Key | PDOCBJADCWMDGL-UHFFFAOYSA-N |
| MSDS | msds/52069_1_130800_90_7.pdf |
| Use of | Sipatrigine, a neuroprotective agent, is a glutamate release inhibitor, voltage-dependent sodium channel and calcium channel inhibitor, penetrating the central nervous system. Has potential to treat focal cerebral ischemia and stroke[1][2]. Properties Name 2-(4-methylpiperazin-1-yl)-5-(2,3,5-trichlorophenyl)pyrimidin-4-amine Synonym More Synonyms Sipatrigine Biological Activity Description Sipatrigine, a neuroprotective agent, is a glutamate release inhibitor, voltage-dependent sodium channel and calcium channel inhibitor, penetrating the central nervous system. Has potential to treat focal cerebral ischemia and stroke[1][2]. Related Catalog Signaling Pathways >> Membrane Transporter/Ion Channel >> Sodium Channel Signaling Pathways >> Membrane Transporter/Ion Channel >> Calcium Channel Research Areas >> Neurological Disease Sodium channel, calcium channel[1][2]. References Chemical & Physical Properties Exact Mass 371.04700 PSA 58.28000 LogP 4.02190 InChIKey PDOCBJADCWMDGL-UHFFFAOYSA-N Safety Information Hazard Codes Xi HS Code 2933990090 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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