![6-(4-Methoxyphenyl)-2-methyl-3,7-dihydroimidazo[1,2-a]pyrazin-3(7H)-one hydrochloride structure, CAS 128322-44-1](/structures/60000/51887_1_128322_44_1.png)
CAS Number128322-44-1
Synonyms2-Methyl-6-(4-methoxyphenyl)-3,7-dihydroimidazo[1,2-a]pyrazin-3-one Hydrochloride; 6-(4-Methoxyphenyl)-2-methyl-3,7-dihydroimidazo[1,2-a]pyrazin-3(7H)-one hydrochloride; 6-(4-methoxyphenyl)-2-methyl-7H-imidazo[1,2-a]pyrazin-3-one,hydrochloride; MFCD00144728; 6-(4-Methoxyphenyl)-2-methylimidazo[1,2-a]pyrazin-3(7H)-one hydrochloride (1:1); Imidazo[1,2-a]pyrazin-3(7H)-one, 6-(4-methoxyphenyl)-2-methyl-, hydrochloride (1:1); 6-(4-Methoxyphenyl)-2-methyl-3,7-dihydroimidazo[1,2-a]pyrazin-3-one Hydrochloride; 6-(4-Methoxyphenyl)-2-methylimidazo[1,2-a]pyrazin-3(7H)-one hydrochloride; MCLA hydrochloride
Molecular FormulaC14H14ClN3O2
Molecular Weight291.73
Purity≥98 (HPLC)%
Boiling Point410.3ºC at 760 mmHg
Appearancepowder
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 128322-44-1 |
| Catalog No. | 2A-9051887 |
| Chinese Name | MCLA盐酸盐 |
| Synonyms | 2-Methyl-6-(4-methoxyphenyl)-3,7-dihydroimidazo[1,2-a]pyrazin-3-one Hydrochloride; 6-(4-Methoxyphenyl)-2-methyl-3,7-dihydroimidazo[1,2-a]pyrazin-3(7H)-one hydrochloride; 6-(4-methoxyphenyl)-2-methyl-7H-imidazo[1,2-a]pyrazin-3-one,hydrochloride; MFCD00144728; 6-(4-Methoxyphenyl)-2-methylimidazo[1,2-a]pyrazin-3(7H)-one hydrochloride (1:1); Imidazo[1,2-a]pyrazin-3(7H)-one, 6-(4-methoxyphenyl)-2-methyl-, hydrochloride (1:1); 6-(4-Methoxyphenyl)-2-methyl-3,7-dihydroimidazo[1,2-a]pyrazin-3-one Hydrochloride; 6-(4-Methoxyphenyl)-2-methylimidazo[1,2-a]pyrazin-3(7H)-one hydrochloride; MCLA hydrochloride |
| Molecular Formula | C14H14ClN3O2 |
| Molecular Weight | 291.73 |
| Purity | ≥98 (HPLC) |
| Boiling Point | 410.3ºC at 760 mmHg |
| Appearance | powder |
| Storage Condition | Sealed and refrigerated |
| Application | MCLA hydrochloride is a chemiluminescent reagent that can be used to quantify the water content of superoxide. |
| HTC | 2933990090 |
| MDL Number | MFCD00144728 |
| SMILES | O=C1C(C)=NC2=CNC(C3=CC=C(OC)C=C3)=CN21.Cl |
| InChI Key | MXZACTZQSGYANA-UHFFFAOYSA-N |
| NACRES Code | NA.21 |
| MSDS | msds/51887_1_128322_44_1.pdf |
| Bioactivity | MCLA hydrochloride is a chemiluminescent reagent which can be used to quantify aqueous concentrations of superoxide. Related Catalog Signaling Pathways >> Others >> Others Dye Reagents Research Areas >> Others In Vitro The non-specific luminescence remains almost constant for 10 min after the addition of MCLA hydrochloride (MCLA) and is not significantly influenced by SOD. The MCLA hydrochloride method is, however, 4.5-times more sensitive than the CLA method[1]. Kinase Assay The standard reaction mixture contains 1×l0-7 M MCLA hydrochloride (MCLA), 5×10-5 M hypoxanthine, XOD (6.5 U), SOD (0.2 to 20 ng/mL) or none, and 50 mM Tris-HCl buffer containing 0.1 mM EDTA at pH 7.8, in a total volume of 3.0 mL. Chemiluminescence measurement is initiated by the addition of MCLA hydrochloride to the standard incubation mixture excluding XOD, continued for 4 min without additive and for an additional 4 min after the addition of XOD. Chemiluminescence is measured using a luminescence reader at 25°C[1]. References [1]. Kimura H, et al. Highly sensitive and reliable chemiluminescence method for the assay of superoxide dismutase inhuman erythrocytes. FEBS Lett. 1988 Nov 7;239(2):347-50. Chemical & Physical Properties Boiling Point 410.3ºC at 760 mmHg Molecular Formula C14H14ClN3O2 Molecular Weight 291.733 Flash Point 201.9ºC Exact Mass 291.077454 PSA 59.39000 LogP 2.80860 Vapour Pressure 3.95E-07mmHg at 25°C InChIKey MXZACTZQSGYANA-UHFFFAOYSA-N SMILES COc1ccc(-c2cn3c(O)c(C)nc3cn2)cc1.Cl Storage condition 2~8°C |
| Use of | MCLA hydrochloride is a chemiluminescent reagent which can be used to quantify aqueous concentrations of superoxide. Properties Name 2-Methyl-6-(4-Methoxyphenyl)-3,7-Dihydroimidazo[1,2-a]Pyrazin-3-One Hydrochloride Synonym More Synonyms MCLA hydrochloride Biological Activity Description MCLA hydrochloride is a chemiluminescent reagent which can be used to quantify aqueous concentrations of superoxide. Related Catalog Signaling Pathways >> Others >> Others Dye Reagents Research Areas >> Others References [1]. Kimura H, et al. Highly sensitive and reliable chemiluminescence method for the assay of superoxide dismutase inhuman erythrocytes. FEBS Lett. 1988 Nov 7;239(2):347-50. Chemical & Physical Properties Exact Mass 291.077454 PSA 59.39000 LogP 2.80860 InChIKey MXZACTZQSGYANA-UHFFFAOYSA-N |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information United Nations classification: inconsistent with United Nations classification standards UN number: not specified |
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