CAS Number723-46-6
SynonymsMFCD00010546; N1-(5-methylisoxazol-3-yl)-4-aminobenzene-1-sulfonamide; SEPTRA; Sulfamethoxazole; 4-Amino-N-(5-methyl-1,2-oxazol-3-yl)benzenesulfonamide; BACTRIM; Sulphamethoxazole; EINECS 211-963-3; Septrin; Gantanol; Sinomin
Molecular FormulaC10H11N3O3S
Molecular Weight253.28
Purity98%
Density1.5±0.1 g/cm3
Boiling Point482.1±55.0 °C at 760 mmHg
Melting Point166 °C
AppearanceCrystal or white powder
EINECS211-963-3
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 723-46-6 |
| Catalog No. | 2A-9005183 |
| Chinese Name | 磺胺甲噁唑 |
| Synonyms | MFCD00010546; N1-(5-methylisoxazol-3-yl)-4-aminobenzene-1-sulfonamide; SEPTRA; Sulfamethoxazole; 4-Amino-N-(5-methyl-1,2-oxazol-3-yl)benzenesulfonamide; BACTRIM; Sulphamethoxazole; EINECS 211-963-3; Septrin; Gantanol; Sinomin |
| Molecular Formula | C10H11N3O3S |
| Molecular Weight | 253.28 |
| Purity | 98 |
| Density | 1.5±0.1 g/cm3 |
| Boiling Point | 482.1±55.0 °C at 760 mmHg |
| Melting Point | 166 °C |
| Appearance | Crystal or white powder |
| Water Solubility | Soluble in: methanol |
| Storage Condition | Store in a sealed, cool, dry and away from light |
| Application | Sulfamethoxazole is a sulfonamide antibiotic and a competitive antagonist of PABA. |
| EINECS | 211-963-3 |
| HTC | 2935003000 |
| PubChem ID | 329824585 |
| MDL Number | MFCD00010546 |
| SMILES | Cc1cc(NS(=O)(=O)c2ccc(N)cc2)no1 |
| InChI | 1S/C10H11N3O3S/c1-7-6-10(12-16-7)13-17(14,15)9-4-2-8(11)3-5-9/h2-6H,11H2,1H3,(H,12,13) |
| InChI Key | JLKIGFTWXXRPMT-UHFFFAOYSA-N |
| Beilstein/REAXYS | 6732984 |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| Hazard Symbols | Transport |
| MSDS | msds/5183_1_723_46_6.pdf |
| Bioactivity | Sulfamethoxazole is a sulfonamide bacteriostatic antibiotic.Target: AntibacterialSulfonamides are structural analogs and competitive antagonists of para-aminobenzoic acid (PABA). They inhibit normal bacterial utilization of PABA for the synthesis of folic acid, an important metabolite in DNA synthesis. The effects seen are usually bacteriostatic in nature. Folic acid is not synthesized in humans, but is instead a dietary requirement. This allows for the selective toxicity to bacterial cells (or any cell dependent on synthesizing folic acid) over human cells. Bacterial resistance to sulfamethoxazole is caused by mutations in the enzymes involved in folic acid synthesis that prevent the drug from binding to it. Related Catalog Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection References [1]. http://en.wikipedia.org/wiki/Sulfamethoxazole Chemical & Physical Properties Density 1.5±0.1 g/cm3 Boiling Point 482.1±55.0 °C at 760 mmHg Melting Point 166 °C Molecular Formula C10H11N3O3S Molecular Weight 253.278 Flash Point 245.4±31.5 °C Exact Mass 253.052109 PSA 106.60000 LogP 0.89 Vapour Pressure 0.0±1.2 mmHg at 25°C Index of Refraction 1.641 InChIKey JLKIGFTWXXRPMT-UHFFFAOYSA-N SMILES Cc1cc(NS(=O)(=O)c2ccc(N)cc2)no1 Storage condition 0-6°C Stability Stable, but light sensitive. Incompatible with strong oxidizing agents. |
| Use of | Sulfamethoxazole is a sulfonamide bacteriostatic antibiotic.Target: AntibacterialSulfonamides are structural analogs and competitive antagonists of para-aminobenzoic acid (PABA). They inhibit normal bacterial utilization of PABA for the synthesis of folic acid, an important metabolite in DNA synthesis. The effects seen are usually bacteriostatic in nature. Folic acid is not synthesized in humans, but is instead a dietary requirement. This allows for the selective toxicity to bacterial cells (or any cell dependent on synthesizing folic acid) over human cells. Bacterial resistance to sulfamethoxazole is caused by mutations in the enzymes involved in folic acid synthesis that prevent the drug from binding to it. Properties Articles99 Name sulfamethoxazole Synonym More Synonyms Sulfamethoxazole Biological Activity Description Sulfamethoxazole is a sulfonamide bacteriostatic antibiotic.Target: AntibacterialSulfonamides are structural analogs and competitive antagonists of para-aminobenzoic acid (PABA). They inhibit normal bacterial utilization of PABA for the synthesis of folic acid, an important metabolite in DNA synthesis. The effects seen are usually bacteriostatic in nature. Folic acid is not synthesized in humans, but is instead a dietary requirement. This allows for the selective toxicity to bacterial cells (or any cell dependent on synthesizing folic acid) over human cells. Bacterial resistance to sulfamethoxazole is caused by mutations in the enzymes involved in folic acid synthesis that prevent the drug from binding to it. Related Catalog Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection References [1]. http://en.wikipedia.org/wiki/Sulfamethoxazole Chemical & Physical Properties Molecular Formula C10H11N3O3S Exact Mass 253.052109 PSA 106.60000 Index of Refraction 1.641 InChIKey JLKIGFTWXXRPMT-UHFFFAOYSA-N Stability Stable, but light sensitive. Incompatible with strong oxidizing agents. |
| Tax Rebate | 9.0% |
| Supervision | None Minimum tariff: 6.5% General tariff: 35.0% |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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