
CAS Number107452-89-1
SynonymsZiconotide; ω-conotoxin MVIIA; SNX-111,Ziconotide; o-Conotoxin MVIIA; SNX-111 Ziconotide; snx111; Ziconotideacetate; Prialt; SNX-111; CKGKGAKCSRLMYDCCTGSCRSGKC-NH2
Molecular FormulaC102H172N36O32S7
Molecular Weight2639.134
Purity98.00%
Density1.6±0.1 g/cm3
Appearancewhite powder
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 107452-89-1 |
| Catalog No. | 2A-9050345 |
| Chinese Name | 醋酸齐考诺肽 |
| Synonyms | Ziconotide; ω-conotoxin MVIIA; SNX-111,Ziconotide; o-Conotoxin MVIIA; SNX-111 Ziconotide; snx111; Ziconotideacetate; Prialt; SNX-111; CKGKGAKCSRLMYDCCTGSCRSGKC-NH2 |
| Molecular Formula | C102H172N36O32S7 |
| Molecular Weight | 2639.134 |
| Purity | 98.00 |
| Density | 1.6±0.1 g/cm3 |
| Appearance | white powder |
| Storage Condition | The warehouse is low-temperature, ventilated, dry, |
| Packaging | III |
| Application | Ziconotide is an analgesic that has been used to treat neuropathic and non-neuropathic pain. Ziconotide acts by binding to N-type calcium channels located at the terminals of primary afferent neurons |
| SMILES | CSCCC1NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(CO)NC(=O)C2CSSCC3NC(=O)C(CO)NC(=O)CNC(=O)C(C(C)O)NC(=O)C(CSSCC(N)C(=O)NC(CCCCN)C(=O)NCC(=O)NC(CCCCN)C(=O)NCC(=O)NC(C)C(=O)NC(CCCCN)C(=O)N2)NC(=O)C(CSSCC(C(N)=O)NC(=O)C(CCCCN)NC(=O)CNC(=O)C(CO)NC(=O)C(CCCNC(=N)N)NC3=O)NC(=O)C(CC(=O)O)NC(=O)C(Cc2ccc(O)cc2)NC1=O |
| InChI Key | BPKIMPVREBSLAJ-UHFFFAOYSA-N |
| Hazard Symbols | 6.1(b) |
| Bioactivity | Ziconotide is an analgesic agent and has been used to treat neuropathic and non-neuropathic pain. Ziconotide acts by binding to N-type calcium channels situated on the terminal part of primary afferent neurons of the nociceptive pathway therefore reducing synaptic transmission with potent antinociceptive effects[1]. Target N-Type Ca2+ Channel References [1]. Brinzeu A, et al. Ziconotide for spinal cord injury-related pain. Eur J Pain. 2019 Oct;23(9):1688-1700. Chemical & Physical Properties Density 1.6±0.1 g/cm3 Molecular Formula C102H172N36O32S7 Molecular Weight 2639.134 Exact Mass 2637.098389 PSA 1310.94000 LogP -17.05 Index of Refraction 1.710 InChIKey BPKIMPVREBSLAJ-UHFFFAOYSA-N SMILES CSCCC1NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(CO)NC(=O)C2CSSCC3NC(=O)C(CO)NC(=O)CNC(=O)C(C(C)O)NC(=O)C(CSSCC(N)C(=O)NC(CCCCN)C(=O)NCC(=O)NC(CCCCN)C(=O)NCC(=O)NC(C)C(=O)NC(CCCCN)C(=O)N2)NC(=O)C(CSSCC(C(N)=O)NC(=O)C(CCCCN)NC(=O)CNC(=O)C(CO)NC(=O)C(CCCNC(=N)N)NC3=O)NC(=O)C(CC(=O)O)NC(=O)C(Cc2ccc(O)cc2)NC1=O |
| Use of | Ziconotide is an analgesic agent and has been used to treat neuropathic and non-neuropathic pain. Ziconotide acts by binding to N-type calcium channels situated on the terminal part of primary afferent neurons of the nociceptive pathway therefore reducing synaptic transmission with potent antinociceptive effects[1]. Properties Articles32 Name Ziconotide acetate Synonym More Synonyms ω-Conotoxin MVIIA Biological Activity Description Ziconotide is an analgesic agent and has been used to treat neuropathic and non-neuropathic pain. Ziconotide acts by binding to N-type calcium channels situated on the terminal part of primary afferent neurons of the nociceptive pathway therefore reducing synaptic transmission with potent antinociceptive effects[1]. N-Type Ca2+ Channel References [1]. Brinzeu A, et al. Ziconotide for spinal cord injury-related pain. Eur J Pain. 2019 Oct;23(9):1688-1700. Chemical & Physical Properties Molecular Formula C102H172N36O32S7 Exact Mass 2637.098389 PSA 1310.94000 LogP -17.05 Index of Refraction 1.710 InChIKey BPKIMPVREBSLAJ-UHFFFAOYSA-N |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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