
CAS Number107233-08-9
Synonyms3]oxathiolane]; CevimelineHClSalt; CEVIMELINE, HYDROCHLORIDE SALT; (2R,2'R)-2'-Methylspiro[4-azabicyclo[2.2.2]octane-2,5'-[1,3]oxathiolane]; cis-2'-Methylspiro[4-azabicyclo[2.2.2]octane-2,5'-[1,3]oxathiolane]; Evoxac; AF-102B; (2R,2'R)-2'-Methylspiro[4-azabicyclo[2.2.2]octan-2,5'-[1,3]oxathiolan]; (2R,2'R)-Cevimeline; Cevimeline; (2R,2'R)-rel-2'-Methylspiro[4-azabicyclo[2.2.2]octane-2,5'-[1,3]oxathiolane]; 3R)-rel; SNI-2011
Molecular FormulaC10H17NOS
Molecular Weight199.31 (anhydrous free base basis)
Purity≥95 (HPLC, NMR)%
Density1.2±0.1 g/cm3
Boiling Point308.5±42.0 °C at 760 mmHg
Melting Point195-197ºC
Appearancepowder
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| Chemical & Physical Properties | |
|---|---|
| CAS Number | 107233-08-9 |
| Catalog No. | 2A-9050333 |
| Chinese Name | 西维美林 |
| Synonyms | 3]oxathiolane]; CevimelineHClSalt; CEVIMELINE, HYDROCHLORIDE SALT; (2R,2'R)-2'-Methylspiro[4-azabicyclo[2.2.2]octane-2,5'-[1,3]oxathiolane]; cis-2'-Methylspiro[4-azabicyclo[2.2.2]octane-2,5'-[1,3]oxathiolane]; Evoxac; AF-102B; (2R,2'R)-2'-Methylspiro[4-azabicyclo[2.2.2]octan-2,5'-[1,3]oxathiolan]; (2R,2'R)-Cevimeline; Cevimeline; (2R,2'R)-rel-2'-Methylspiro[4-azabicyclo[2.2.2]octane-2,5'-[1,3]oxathiolane]; 3R)-rel; SNI-2011 |
| Molecular Formula | C10H17NOS |
| Molecular Weight | 199.31 (anhydrous free base basis) |
| Purity | ≥95 (HPLC, NMR) |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 308.5±42.0 °C at 760 mmHg |
| Melting Point | 195-197ºC |
| Appearance | powder |
| Storage Condition | -20°C |
| Application | Cevimeline (Evoxac) is a parasympathomimetic and muscarinic agonist with partial agonistic effects on M3 receptors. |
| PubChem ID | 329825084 |
| SMILES | O.Cl.Cl.C[C@@H]1O[C@@]2(CS1)CN3CC[C@H]2CC3.C[C@@H]4O[C@@]5(CS4)CN6CC[C@H]5CC6 |
| InChI | 1S/2C10H17NOS.2ClH.H2O/c2*1-8-12-10(7-13-8)6-11-4-2-9(10)3-5-11;;;/h2*8-9H,2-7H2,1H3;2*1H;1H2/t2*8-,10-;;;/m11.../s1 |
| InChI Key | ZSTLCHCDLIUXJE-GMLJRNIPSA-N |
| NACRES Code | NA.77 |
| UNSPSC | 12352200 |
| MSDS | msds/50333_1_107233_08_9.pdf |
| Transport Info | Product name: Cevimeline |
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