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Home > Products > Pharmaceuticals & Life Science > Biotechnology & Diagnostics > N-Benzoyl-5'-O-(4,4-Dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]adenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
N-Benzoyl-5'-O-(4,4-Dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]adenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite structure, CAS 104992-55-4

N-Benzoyl-5'-O-(4,4-Dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]adenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite

CAS Number104992-55-4

SynonymsBz-rA Phosphoramidite; Bz-rAPhosphoramidite

Molecular FormulaC53H66N7O8PSi

Molecular Weight988.19

Purity≥99 (<SUP>31</SUP>P-NMR)%

Density

Boiling Point

Melting Point

Flash Point

Appearancepowder

EINECS

MSDSChineseEnglish

Symbol

Signal Word

Cat. No.: 2A-9050156 Purity: ≥99 (<SUP>31</SUP>P-NMR)%
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Quality Control of [ 104992-55-4 ] Purity: ≥99 (<SUP>31</SUP>P-NMR)% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number104992-55-4
Catalog No.2A-9050156
Chinese NameN-苯甲酰基-5'-O-(4,4-二甲氧基三苯甲基)-2'-O-[(叔丁基)二甲基硅基]腺苷-3'-(2-氰基乙基-N,N-二异丙基)亚磷酰胺
SynonymsBz-rA Phosphoramidite; Bz-rAPhosphoramidite
Molecular FormulaC53H66N7O8PSi
Molecular Weight988.19
Purity≥99 (<SUP>31</SUP>P-NMR)
Appearancepowder
Storage Conditionroom temperature, dry
ApplicationBz-rA Phosphoramidite can be used for modification of nucleotides.
PubChem ID329770730
MDL NumberMFCD00080297
SMILESCOc1ccc(cc1)C(OC[C@H]2O[C@H]([C@H](O[Si](C)(C)C(C)(C)C)[C@@H]2OP(OCCC#N)N(C(C)C)C(C)C)n3cnc4c(NC(=O)c5ccccc5)ncnc34)(c6ccccc6)c7ccc(OC)cc7
InChI1S/C53H66N7O8PSi/c1-36(2)60(37(3)4)69(65-32-18-31-54)67-46-44(33-64-53(39-21-16-13-17-22-39,40-23-27-42(62-8)28-24-40)41-25-29-43(63-9)30-26-41)66-51(47(46)68-70(10,11)52(5,6)7)59-35-57-45-48(55-34-56-49(45)59)58-50(61)38-19-14-12-15-20-38/h12-17,19-30,34-37,44,46-47,51H,18,32-33H2,1-11H3,(H,55,56,58,61)/t44-,46-,47-,51-,69?/m1/s1
InChI KeyFFXHNCNNHASXCT-RFMFGJHUSA-N
NACRES CodeNA.51
UNSPSC12352200
MSDSmsds/50156_1_104992_55_4.pdf
BioactivityBz-rA Phosphoramidite is used for ribonucleotides modification[1]. Related Catalog Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis Research Areas >> Others References [1]. Elise Malek-Adamian, et al. 4'-C-Methoxy-2'-deoxy-2'-fluoro Modified Ribonucleotides Improve Metabolic Stability and Elicit Efficient RNAi-Mediated Gene Silencing. J Am Chem Soc. 2017 Oct 18;139(41):14542-14555. Chemical & Physical Properties Molecular Formula C53H66N7O8PSi Molecular Weight 988.193 Exact Mass 987.447998 PSA 177.93000 LogP 13.07 InChIKey FFXHNCNNHASXCT-RFMFGJHUSA-N SMILES COc1ccc(C(OCC2OC(n3cnc4c(NC(=O)c5ccccc5)ncnc43)C(O[Si](C)(C)C(C)(C)C)C2OP(OCCC#N)N(C(C)C)C(C)C)(c2ccccc2)c2ccc(OC)cc2)cc1
Use ofBz-rA Phosphoramidite is used for ribonucleotides modification[1]. Properties Name N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[tert-butyl(dimethyl)silyl]oxy-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]purin-6-yl]benzamide Synonym More Synonyms Bz-rA Phosphoramidite Biological Activity Description Bz-rA Phosphoramidite is used for ribonucleotides modification[1]. Related Catalog Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis Research Areas >> Others References [1]. Elise Malek-Adamian, et al. 4'-C-Methoxy-2'-deoxy-2'-fluoro Modified Ribonucleotides Improve Metabolic Stability and Elicit Efficient RNAi-Mediated Gene Silencing. J Am Chem Soc. 2017 Oct 18;139(41):14542-14555. Chemical & Physical Properties Molecular Formula C53H66N7O8PSi Exact Mass 987.447998 PSA 177.93000 LogP 13.07 InChIKey FFXHNCNNHASXCT-RFMFGJHUSA-N
Transport InfoProduct name: N-benzoyl-5'-O-(4,4-dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]adenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
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