CAS Number101328-85-2
Synonyms6-(4-Amino-phenyl)-5-methyl-4,5-dih; ydro-2H-pyridazin-3-one; (R)-6-(4-Aminophenyl)-4,5-dihydro-5-methyl-3(2H)-pyridazinone; MFCD01692712; 6-(4-Aminophenyl)-5-methyl-4,5-dihydropyridazin-3(2H)-one; 6-(4-Aminophenyl)-5-methyl-4,5-dihydro-3(2H)-pyridazinone
Molecular FormulaC11H13O1N3
Molecular Weight203.24
Purity98.00%
Density1.3±0.1 g/cm3
Melting Point206-208ºC
AppearanceLight yellow solid
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 101328-85-2 |
| Catalog No. | 2A-9049810 |
| Chinese Name | (R)-6-(4-氨基苯基)-4,5-二氢-5-甲基-3(2H)-哒嗪酮 |
| Synonyms | 6-(4-Amino-phenyl)-5-methyl-4,5-dih; ydro-2H-pyridazin-3-one; (R)-6-(4-Aminophenyl)-4,5-dihydro-5-methyl-3(2H)-pyridazinone; MFCD01692712; 6-(4-Aminophenyl)-5-methyl-4,5-dihydropyridazin-3(2H)-one; 6-(4-Aminophenyl)-5-methyl-4,5-dihydro-3(2H)-pyridazinone |
| Molecular Formula | C11H13O1N3 |
| Molecular Weight | 203.24 |
| Purity | 98.00 |
| Density | 1.3±0.1 g/cm3 |
| Melting Point | 206-208ºC |
| Appearance | Light yellow solid |
| Storage Condition | -20?C Freezer |
| Application | OR-1855 is the active metabolite of Levosimendan and affects human muscle contractility. Levosimendan is a calcium-sensitive drug used to treat acute decompensated congestive heart failure. |
| HTC | 2933990090 |
| PubChem ID | 15487957 |
| MDL Number | MFCD09032921 |
| SMILES | CC1CC(=O)NN=C1c1ccc(N)cc1 |
| InChI | InChI=1S/C11H13N3O/c1-7-6-10(15)13-14-11(7)8-2-4-9(12)5-3-8/h2-5,7H,6,12H2,1H3,(H,13,15)/t7-/m1/s1 |
| InChI Key | GDMRFHZLKNYRRO-SSDOTTSWSA-N |
| MSDS | msds/49810_1_101328_85_2.pdf |
| Use of | OR-1855, an active metabolite of Levosimendan, has effect on human myometrial contractility. Levosimendan is a calcium sensitiser used in the management of acutely decompensated congestive heart failure[1][2]. Properties Name (R)-6-(4-Aminophenyl)-5-methyl-4,5-dihydropyridazin-3(2H)-one Synonym More Synonyms OR-1855 Biological Activity Description OR-1855, an active metabolite of Levosimendan, has effect on human myometrial contractility. Levosimendan is a calcium sensitiser used in the management of acutely decompensated congestive heart failure[1][2]. Related Catalog Research Areas >> Cardiovascular Disease Signaling Pathways >> Others >> Others References [2]. Mark P. Hehir, et al. 487: OR-1855, a levosimendan metabolite with an effect on human myometrial contractility.December 2009Volume 201, Issue 6, Supplement, Pages S182-S183. Chemical & Physical Properties Molecular Formula C11H13N3O Exact Mass 203.105865 PSA 67.48000 LogP -0.75 Index of Refraction 1.653 InChIKey GDMRFHZLKNYRRO-SSDOTTSWSA-N Storage condition -20?C Freezer Safety Information Hazard Codes Xi HS Code 2933990090 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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