CAS Number82964-04-3
Synonyms[(6-Methoxy-5-trifluoromethyl-naphthalene-1-carbothioyl)-methyl-amino]-acetic acid; 2-[[6-methoxy-5-(trifluoromethyl)naphthalene-1-carbothioyl]-methylamino]acetic acid; N-{[6-Methoxy-5-(trifluoromethyl)-1-naphthyl]carbothioyl}-N-methylglycine; N-{[6-Methoxy-5-(trifluoromethyl)-1-naphthyl]carbonothioyl}-N-methylglycine; N-[[6-Methoxy-5-(trifluoromethyl)-1-naphthalenyl]thioxomethyl]-N-methylglycine; AY-27,773; Tolrestatum [Latin]; N-(6-Methoxythio-5-(trifluoromethyl)-1-naphthoyl)sarcosine; Alredase; N-{[6-methoxy-5-(trifluoromethyl)naphthalen-1-yl]carbothioyl}-N-methylglycine; Tolrestatum; Tolrestat
Molecular FormulaC16H14F3NO3S
Molecular Weight357.35
Purity≥98 (HPLC)%
Density1.4±0.1 g/cm3
Boiling Point498.1±55.0 °C at 760 mmHg
Melting Point164-165°
Appearancepowder
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 82964-04-3 |
| Catalog No. | 2A-9048836 |
| Chinese Name | 托雷斯萘 |
| Synonyms | [(6-Methoxy-5-trifluoromethyl-naphthalene-1-carbothioyl)-methyl-amino]-acetic acid; 2-[[6-methoxy-5-(trifluoromethyl)naphthalene-1-carbothioyl]-methylamino]acetic acid; N-{[6-Methoxy-5-(trifluoromethyl)-1-naphthyl]carbothioyl}-N-methylglycine; N-{[6-Methoxy-5-(trifluoromethyl)-1-naphthyl]carbonothioyl}-N-methylglycine; N-[[6-Methoxy-5-(trifluoromethyl)-1-naphthalenyl]thioxomethyl]-N-methylglycine; AY-27,773; Tolrestatum [Latin]; N-(6-Methoxythio-5-(trifluoromethyl)-1-naphthoyl)sarcosine; Alredase; N-{[6-methoxy-5-(trifluoromethyl)naphthalen-1-yl]carbothioyl}-N-methylglycine; Tolrestatum; Tolrestat |
| Molecular Formula | C16H14F3NO3S |
| Molecular Weight | 357.35 |
| Purity | ≥98 (HPLC) |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 498.1±55.0 °C at 760 mmHg |
| Melting Point | 164-165° |
| Appearance | powder |
| Storage Condition | 2-8℃ |
| Application | Tolrestat is a potent, orally available aldose reductase inhibitor with an IC50 of 35 nM. |
| PubChem ID | 4773 |
| SMILES | FC(F)(F)c1c2c(c(ccc2)C(=S)N(CC(=O)O)C)ccc1OC |
| InChI | 1S/C16H14F3NO3S/c1-20(8-13(21)22)15(24)11-5-3-4-10-9(11)6-7-12(23-2)14(10)16(17,18)19/h3-7H,8H2,1-2H3,(H,21,22) |
| InChI Key | LUBHDINQXIHVLS-UHFFFAOYSA-N |
| NACRES Code | NA.77 |
| UNSPSC | 12352200 |
| MSDS | msds/48836_1_82964_04_3.pdf |
| Transport Info | Product Name: Tolrestat |
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