CAS Number82911-78-2
SynonymsSerine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, methyl ester; Methyl N-[(9H-fluoren-9-ylmethoxy)carbonyl]serinate; methyl (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-hydroxypropanoate; Fmoc-Ser-Ome
Molecular FormulaC19H19O5N1
Molecular Weight341.36
Purity98.00%
Density1.3±0.1 g/cm3
Boiling Point579.4±45.0 °C at 760 mmHg
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 82911-78-2 |
| Catalog No. | 2A-9048827 |
| Chinese Name | fmoc-l-丝氨酸甲酯 |
| Synonyms | Serine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, methyl ester; Methyl N-[(9H-fluoren-9-ylmethoxy)carbonyl]serinate; methyl (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-hydroxypropanoate; Fmoc-Ser-Ome |
| Molecular Formula | C19H19O5N1 |
| Molecular Weight | 341.36 |
| Purity | 98.00 |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 579.4±45.0 °C at 760 mmHg |
| Storage Condition | -15°C |
| Application | Fmoc-Ser-OMe (Fmoc-L-Ser-OMe) is a hydroxylated L-amino acid protected by 9-fluorenylmethyloxycarbonyl (Fmoc). Fmoc-Ser-OMe participates in the synthesis of chlorophyll-amino acid conjugates as a pigm |
| HTC | 2924299090 |
| PubChem ID | 16220234 |
| MDL Number | MFCD00672334 |
| SMILES | COC(=O)C(CO)NC(=O)OCC1c2ccccc2-c2ccccc21 |
| InChI | InChI=1S/C19H19NO5/c1-24-18(22)17(10-21)20-19(23)25-11-16-14-8-4-2-6-12(14)13-7-3-5-9-15(13)16/h2-9,16-17,21H,10-11H2,1H3,(H,20,23)/t17-/m0/s1 |
| InChI Key | QQQVLIVWQMWACQ-KRWDZBQOSA-N |
| MSDS | msds/48827_1_82911_78_2.pdf |
| Use of | Fmoc-Ser-OMe (Fmoc-L-Ser-OMe) is a hydroxylated L-amino acid protected with a 9-fluorenylmethyloxycarbonyl (Fmoc) group. Fmoc-Ser-OMe involves in chlorophyll-amino acid conjugates synthesis, and acts as a chromo/fluorophores modified protein and emits visible to near-infrared lights efficiently. Fmoc-Ser-OMe glycosylates and produces small mucin-related Olinked glycopeptides, as an alcohol acceptor[1][2]. Properties Name (S)-Methyl 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-hydroxypropanoate Synonym More Synonyms Fmoc-ser-ome Biological Activity Description Fmoc-Ser-OMe (Fmoc-L-Ser-OMe) is a hydroxylated L-amino acid protected with a 9-fluorenylmethyloxycarbonyl (Fmoc) group. Fmoc-Ser-OMe involves in chlorophyll-amino acid conjugates synthesis, and acts as a chromo/fluorophores modified protein and emits visible to near-infrared lights efficiently. Fmoc-Ser-OMe glycosylates and produces small mucin-related Olinked glycopeptides, as an alcohol acceptor[1][2]. Related Catalog Research Areas >> Others Signaling Pathways >> Others >> Others References [1]. Tamiaki H, et al. Synthesis of chlorophyll-amino acid conjugates as models for modification of proteins with chromo/fluorophores. Bioorg Med Chem. 2014 Feb 15;22(4):1421-8. [2]. Kärkkäinen TS, et al. Iodine-mediated glycosylation en route to mucin-related glyco-aminoacids and glycopeptides. Carbohydr Res. 2008 Jul 21;343(10-11):1830-4. Chemical & Physical Properties Molecular Formula C19H19NO5 Exact Mass 341.126312 PSA 88.35000 Index of Refraction 1.595 InChIKey QQQVLIVWQMWACQ-KRWDZBQOSA-N Safety Information HS Code 2924299090 Synthetic Route H-Ser-Ome·HCl CAS#:5680-80-8 CAS#:82911-69-1 Fmoc-ser-ome CAS#:82911-78-2 Literature: Shao, Hui; Lockman, Jeffrey W.; Parquette, Jon R. Journal of the American Chemical Society, 2007 , vol. 129, # 7 p. 1884 - 1885 Fmoc-Ser-OH CAS#:73724-45-5 methyl iodide CAS#:74-88-4 Fmoc-ser-ome CAS#:82911-78-2 Literature: Zhang, Fa; Zhang, Wei; Zhang, Yan; Curran, Dennis P.; Liu, Gang Journal of Organic Chemistry, 2009 , vol. 74, # 6 p. 2594 - 2597 diazomethane CAS#:186581-53-3 Fmoc-Ser-OH CAS#:73724-45-5 Fmoc-ser-ome CAS#:82911-78-2 Literature: Bioorganic and Medicinal Chemistry, , vol. 22, # 4 p. 1421 - 1428 Precursor & DownStream Precursor 10 CAS#:5680-80-8 H-Ser-Ome·HCl CAS#:82911-69-1 CAS#:73724-45-5 Fmoc-Ser-OH CAS#:74-88-4 methyl iodide DownStream 5 CAS#:282734-37-6 2-PYRIDINEPROPA... CAS#:73724-45-5 Fmoc-Ser-OH CAS#:156017-42-4 N-Fmoc-3-iodo-L... CAS#:185379-40-2 Fmoc-L-2-Pyridy... |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 30.0% |
| Transport Info | Product name: Summary 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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