CAS Number81732-46-9
Synonyms(±)-Bambuterol hydrochloride; Bambuterol hydrochloride; 5-[2-(tert-Butylamino)-1-hydroxyethyl]-1,3-phenylene bis(dimethylcarbamate) hydrochloride (1:1); 5-[2-(tert-butylamino)-1-hydroxyethyl]benzene-1,3-diyl bis(dimethylcarbamate) hydrochloride (1:1); UNII:786Q84QZ3F; MFCD03427293; Bambec; Bambuterol (hydrochloride)
Molecular FormulaC18H29N3O5 · HCl
Molecular Weight403.90
Purity98.00%
Density1.154g/cm3
Boiling Point500.9ºC at 760 mmHg
Melting Point222-224ºC
Appearancewhite solid
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 81732-46-9 |
| Catalog No. | 2A-9048657 |
| Chinese Name | 盐酸班布特罗 |
| Synonyms | (±)-Bambuterol hydrochloride; Bambuterol hydrochloride; 5-[2-(tert-Butylamino)-1-hydroxyethyl]-1,3-phenylene bis(dimethylcarbamate) hydrochloride (1:1); 5-[2-(tert-butylamino)-1-hydroxyethyl]benzene-1,3-diyl bis(dimethylcarbamate) hydrochloride (1:1); UNII:786Q84QZ3F; MFCD03427293; Bambec; Bambuterol (hydrochloride) |
| Molecular Formula | C18H29N3O5 · HCl |
| Molecular Weight | 403.90 |
| Purity | 98.00 |
| Density | 1.154g/cm3 |
| Boiling Point | 500.9ºC at 760 mmHg |
| Melting Point | 222-224ºC |
| Appearance | white solid |
| Water Solubility | H2O: ~33 mg/mL, soluble |
| Storage Condition | -20°C Freezer |
| Application | Bambuterol hydrochloride is a long-acting adrenergic receptor agonist and the prodrug of Terbutaline. |
| PubChem ID | 329773104 |
| MDL Number | MFCD03427293 |
| SMILES | Cl.CN(C)C(=O)Oc1cc(OC(=O)N(C)C)cc(c1)C(O)CNC(C)(C)C |
| InChI | 1S/C18H29N3O5.ClH/c1-18(2,3)19-11-15(22)12-8-13(25-16(23)20(4)5)10-14(9-12)26-17(24)21(6)7;/h8-10,15,19,22H,11H2,1-7H3;1H |
| InChI Key | LBARATORRVNNQM-UHFFFAOYSA-N |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| Hazard Symbols | transportation |
| MSDS | msds/48657_1_81732_46_9.pdf |
| Bioactivity | Bambuterol Hcl is a long acting beta-adrenoceptor agonist (LABA) used in the treatment of asthma; it also is a prodrug of terbutaline.IC50 value:Target: beta-adrenoceptor agonistBambuterol is contraindicated in pregnancy and in people with seriously impaired liver function. It can be used by people with renal impairment, but dose adjustments are necessary. The adverse effect profile of bambuterol is similar to that of salbutamol, and may include fatigue, nausea, palpitations, headache, dizziness and tremor. Related Catalog Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor Research Areas >> Others References [1]. Bambuterol, From Wikipedia Chemical & Physical Properties Density 1.154g/cm3 Boiling Point 500.9ºC at 760 mmHg Melting Point 222-224ºC Molecular Formula C18H30ClN3O5 Molecular Weight 403.901 Flash Point 256.7ºC Exact Mass 403.187408 PSA 91.34000 LogP 3.42180 Index of Refraction 1.533 InChIKey LBARATORRVNNQM-UHFFFAOYSA-N SMILES CN(C)C(=O)Oc1cc(OC(=O)N(C)C)cc(C(O)CNC(C)(C)C)c1.Cl Storage condition -20°C Freezer Water Solubility H2O: ~33 mg/mL, soluble |
| Use of | Bambuterol Hcl is a long acting beta-adrenoceptor agonist (LABA) used in the treatment of asthma; it also is a prodrug of terbutaline.IC50 value:Target: beta-adrenoceptor agonistBambuterol is contraindicated in pregnancy and in people with seriously impaired liver function. It can be used by people with renal impairment, but dose adjustments are necessary. The adverse effect profile of bambuterol is similar to that of salbutamol, and may include fatigue, nausea, palpitations, headache, dizziness and tremor. Properties Name bambuterol hydrochloride Synonym More Synonyms Bambuterol Hydrochloride Biological Activity Description Bambuterol Hcl is a long acting beta-adrenoceptor agonist (LABA) used in the treatment of asthma; it also is a prodrug of terbutaline.IC50 value:Target: beta-adrenoceptor agonistBambuterol is contraindicated in pregnancy and in people with seriously impaired liver function. It can be used by people with renal impairment, but dose adjustments are necessary. The adverse effect profile of bambuterol is similar to that of salbutamol, and may include fatigue, nausea, palpitations, headache, dizziness and tremor. Related Catalog Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor Research Areas >> Others References [1]. Bambuterol, From Wikipedia Chemical & Physical Properties Exact Mass 403.187408 PSA 91.34000 LogP 3.42180 Index of Refraction 1.533 InChIKey LBARATORRVNNQM-UHFFFAOYSA-N |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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