CAS Number80307-12-6
SynonymsMFCD00036817; (2,5-dioxopyrrolidin-1-yl) 4-(2,5-dioxopyrrol-1-yl)butanoate; 1-{4-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-4-oxobutyl}-1H-pyrrole-2,5-dione; 1-{4-[(2,5-Dioxopyrrolidin-1-yl)oxy]-4-oxobutyl}-1H-pyrrole-2,5-dione
Molecular FormulaC12H12N2O6
Molecular Weight280.23
Purity≥98.0 (HPLC)%
Density1.5±0.1 g/cm3
Boiling Point461.3±47.0 °C at 760 mmHg
Melting Point123-129 °C
Appearancewhite solid
Symbol
Signal WordWarning
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| Chemical & Physical Properties | |
|---|---|
| CAS Number | 80307-12-6 |
| Catalog No. | 2A-9048466 |
| Chinese Name | N-(4-马来酰亚胺丁酰基)琥珀酰亚胺 |
| Synonyms | MFCD00036817; (2,5-dioxopyrrolidin-1-yl) 4-(2,5-dioxopyrrol-1-yl)butanoate; 1-{4-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-4-oxobutyl}-1H-pyrrole-2,5-dione; 1-{4-[(2,5-Dioxopyrrolidin-1-yl)oxy]-4-oxobutyl}-1H-pyrrole-2,5-dione |
| Molecular Formula | C12H12N2O6 |
| Molecular Weight | 280.23 |
| Purity | ≥98.0 (HPLC) |
| Density | 1.5±0.1 g/cm3 |
| Boiling Point | 461.3±47.0 °C at 760 mmHg |
| Melting Point | 123-129 °C |
| Appearance | white solid |
| Water Solubility | chloroform: 100 mg/mL |
| Storage Condition | 2 -8 °C |
| Application | GMBS is a bifunctional cross-linking agent. GMBS is commonly used to prepare antibody-enzyme and hapten-carrier protein conjugates. |
| HTC | 2925190090 |
| PubChem ID | 329759802 |
| MDL Number | MFCD00036817 |
| SMILES | O=C1N(CCCC(ON2C(CCC2=O)=O)=O)C(C=C1)=O |
| InChI | 1S/C12H12N2O6/c15-8-3-4-9(16)13(8)7-1-2-12(19)20-14-10(17)5-6-11(14)18/h3-4H,1-2,5-7H2 |
| InChI Key | PVGATNRYUYNBHO-UHFFFAOYSA-N |
| Beilstein/REAXYS | 6427689 |
| NACRES Code | NA.25 |
| UNSPSC | 12352106 |
| Hazard Symbols | transportation |
| MSDS | msds/48466_1_80307_12_6.pdf |
| Bioactivity | GMBS is a heterobifunctional cross-linker. GMBS is often used to prepare antibody-enzyme and hapten-carrier protein conjugates. Related Catalog Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker References [1]. Ding YH, et al. Increasing the Depth of Mass-Spectrometry-Based Structural Analysis of Protein Complexes through the Use of Multiple Cross-Linkers. Anal Chem. 2016 Apr 19;88(8):4461-9. Chemical & Physical Properties Density 1.5±0.1 g/cm3 Boiling Point 461.3±47.0 °C at 760 mmHg Melting Point 123-129ºC Molecular Formula C12H12N2O6 Molecular Weight 280.233 Flash Point 232.8±29.3 °C Exact Mass 280.069550 PSA 101.06000 LogP -1.56 Vapour Pressure 0.0±1.1 mmHg at 25°C Index of Refraction 1.595 InChIKey PVGATNRYUYNBHO-UHFFFAOYSA-N SMILES O=C(CCCN1C(=O)C=CC1=O)ON1C(=O)CCC1=O Storage condition 2-8°C Water Solubility chloroform: 100 mg/mL |
| Use of | GMBS is a heterobifunctional cross-linker. GMBS is often used to prepare antibody-enzyme and hapten-carrier protein conjugates. Properties Articles29 Name 4-Maleimidobutyric Acid N-Succinimidyl Ester Synonym More Synonyms gmbs Biological Activity Description GMBS is a heterobifunctional cross-linker. GMBS is often used to prepare antibody-enzyme and hapten-carrier protein conjugates. Related Catalog Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker References [1]. Ding YH, et al. Increasing the Depth of Mass-Spectrometry-Based Structural Analysis of Protein Complexes through the Use of Multiple Cross-Linkers. Anal Chem. 2016 Apr 19;88(8):4461-9. Chemical & Physical Properties Molecular Formula C12H12N2O6 Exact Mass 280.069550 PSA 101.06000 LogP -1.56 Index of Refraction 1.595 InChIKey PVGATNRYUYNBHO-UHFFFAOYSA-N |
| Tax Rebate | 9.0% |
| Supervision | None MFN tariff: 6.5% Ordinary tariff: 30.0% |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available The above information is believed to be correct, but is not all-inclusive and should be used as a guide only. The information in this document is based on our current knowledge and is Correct safety instructions apply to this product. This information does not represent a warranty as to the properties of this product. See reverse side of invoice or packing slip. |
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