CAS Number77182-82-2
SynonymsGlufosinate Ammonium; 2-Amino-4-(hydroxymethylphosphinyl)butyric acid ammonium salt; 2-Amino-4-(hydroxymethylphosphinyl)butanoic acid, monoammonium salt; DL-Phosphinothricin, monoammonium salt; 2-Amino-4-(hydroxymethylphosphinyl)butanoic acid monoammonium salt; 2-Amino-4-[hydroxy(methyl)phosphoryl]butanoic acid ammoniate (1:1); Glufosinate ammonium salt; Ammonium (3-amino-3-carboxypropyl)methylphosphinate; ammonium (2RS)-2-amino-4-(methylphosphinato)butyric acid; Monoammonium 2-amino-4-(hydroxymethylphosphinyl)butanoate; Ammonium 2-amino-4-(hydroxymethylphosphinyl)butyrate; Basta; Monoammonium 4-[hydroxy(methyl)phosphinoyl]-DL-homoalaninate; 2-Amino-4-[hydroxy(methyl)phosphoryl]butanoic acid ammoniate; QVYZ2PQO&1 &&(DL) Form NH4 Salt; Ammonium (DL-homoalanine-4-yl)methylphosphinate; Glufos
Molecular FormulaC5H15N2O4P
Molecular Weight198.16
Purity98.00%
Boiling Point519.1ºC at 760 mmHg
Melting Point210°C
Appearancecrystalline solid
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 77182-82-2 |
| Catalog No. | 2A-9048091 |
| Chinese Name | 草铵膦 |
| Synonyms | Glufosinate Ammonium; 2-Amino-4-(hydroxymethylphosphinyl)butyric acid ammonium salt; 2-Amino-4-(hydroxymethylphosphinyl)butanoic acid, monoammonium salt; DL-Phosphinothricin, monoammonium salt; 2-Amino-4-(hydroxymethylphosphinyl)butanoic acid monoammonium salt; 2-Amino-4-[hydroxy(methyl)phosphoryl]butanoic acid ammoniate (1:1); Glufosinate ammonium salt; Ammonium (3-amino-3-carboxypropyl)methylphosphinate; ammonium (2RS)-2-amino-4-(methylphosphinato)butyric acid; Monoammonium 2-amino-4-(hydroxymethylphosphinyl)butanoate; Ammonium 2-amino-4-(hydroxymethylphosphinyl)butyrate; Basta; Monoammonium 4-[hydroxy(methyl)phosphinoyl]-DL-homoalaninate; 2-Amino-4-[hydroxy(methyl)phosphoryl]butanoic acid ammoniate; QVYZ2PQO&1 &&(DL) Form NH4 Salt; Ammonium (DL-homoalanine-4-yl)methylphosphinate; Glufos |
| Molecular Formula | C5H15N2O4P |
| Molecular Weight | 198.16 |
| Purity | 98.00 |
| Boiling Point | 519.1ºC at 760 mmHg |
| Melting Point | 210°C |
| Appearance | crystalline solid |
| Water Solubility | Water solubility: completely dissolved; water solu |
| Storage Condition | Warehouse ventilation and low temperature drying |
| Packaging | III |
| Application | Glufosinate ammonium is a phosphonic acid analogue of glutamic acid, a herbicide converted into PT (L-phosphinothricin) by plant cells. Glufosinate ammonium has neurotoxic effects. |
| HTC | 2931901917 |
| PubChem ID | 329757504 |
| SMILES | CP(=O)(O)CCC(N)C(=O)O.N |
| InChI | InChI=1S/C5H12NO4P.H3N/c1-11(9,10)3-2-4(6)5(7)8;/h4H,2-3,6H2,1H3,(H,7,8)(H,9,10);1H3 |
| InChI Key | ZBMRKNMTMPPMMK-UHFFFAOYSA-N |
| Hazard Symbols | 6.1(b) |
| Bioactivity | Glufosinate ammonium, a phosphinic acid analogue of glutamic acid, is an herbicide which is converted by plant cells into PT (L-phosphinothricin). Glufosinate ammonium exerts neurotoxic activity[1][2]. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease In Vitro Glufosinate ammonium (1-100 μM; 12DIV) disrupts cell-cell adhesion in differentiated V-SVZ neural stem cells (NSCs)[2]. Glufosinate ammonium (1-100 μM; 12DIV) significantly decreases Celsr2 gene expression at 100 μM[2]. Glufosinate ammonium impairs ependymal cell capability to synthetize cilia[2]. RT-PCR[2] Cell Line: Ependymal cells Concentration: 1, 3, 10, 100 μM Incubation Time: During 12DIV (NSCs-to-ependymal cells time point) Result: Significantly decreased Celsr2 gene expression at 100 μM. In Vivo Glufosinate ammonium (10-250 mg/kg; gavage; Daily; on days 6-15 of gestation) indicates maternal toxicity in the groups given 50 or 250 mg/kg in Wistar rats[3]. The Elimination of Glufosinate ammonium (oral intubation) in the blood takes place with a half-life of less than 4 hours in male and female rats[3]. References [1]. Áy Z, et al. The effect of high concentrations of glufosinate ammonium on the yield components of transgenic spring wheat (Triticum aestivum L.) constitutively expressing the bar gene. ScientificWorldJournal. 2012;2012:657945. [2]. Feat-Vetel J, et al. Multiple effects of the herbicide glufosinate-ammonium and its main metabolite on neural stem cells from the subventricular zone of newborn mice. Neurotoxicology. 2018 Dec;69:152-163. [3]. Ebert E, et al. Summary of safety evaluation toxicity studies of glufosinate ammonium. Food Chem Toxicol. 1990 May;28(5):339-49. Chemical & Physical Properties Boiling Point 519.1ºC at 760 mmHg Melting Point 210°C Molecular Formula C5H15N2O4P Molecular Weight 215.18800 Flash Point 100 °C Exact Mass 215.10300 PSA 116.09000 LogP 0.24480 InChIKey ZBMRKNMTMPPMMK-UHFFFAOYSA-N SMILES CP(=O)(O)CCC(N)C(=O)O.N Stability Stable. Incompatible with strong oxidizing agents. |
| Use of | Glufosinate ammonium, a phosphinic acid analogue of glutamic acid, is an herbicide which is converted by plant cells into PT (L-phosphinothricin). Glufosinate ammonium exerts neurotoxic activity[1][2]. Properties Articles13 Name glufosinate-ammonium Synonym More Synonyms Glufosinate ammonium Biological Activity Description Glufosinate ammonium, a phosphinic acid analogue of glutamic acid, is an herbicide which is converted by plant cells into PT (L-phosphinothricin). Glufosinate ammonium exerts neurotoxic activity[1][2]. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease References [1]. Áy Z, et al. The effect of high concentrations of glufosinate ammonium on the yield components of transgenic spring wheat (Triticum aestivum L.) constitutively expressing the bar gene. ScientificWorldJournal. 2012;2012:657945. [2]. Feat-Vetel J, et al. Multiple effects of the herbicide glufosinate-ammonium and its main metabolite on neural stem cells from the subventricular zone of newborn mice. Neurotoxicology. 2018 Dec;69:152-163. [3]. Ebert E, et al. Summary of safety evaluation toxicity studies of glufosinate ammonium. Food Chem Toxicol. 1990 May;28(5):339-49. Chemical & Physical Properties Molecular Formula C5H15N2O4P Exact Mass 215.10300 PSA 116.09000 LogP 0.24480 InChIKey ZBMRKNMTMPPMMK-UHFFFAOYSA-N SMILES CP(=O)(O)CCC(N)C(=O)O.N Stability Stable. Incompatible with strong oxidizing agents. |
| Tax Rebate | 13.0% |
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| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
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