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Cefmenoxime hydrochloride structure, CAS 75738-58-8

Cefmenoxime hydrochloride

CAS Number75738-58-8

SynonymsApatef; SCE 1365 hydrochloride; Yamatetan; Cepan Darvilen; Apacef; Bestcall; CEFOTETAN; Cefotetan acid; Tacef; Cefmenoxime hydrochloride; Ceftenon; Abbott 50192 (HCl); CEFOTETAN SODIUM; Cefmenoxime (hydrochloride)

Molecular FormulaC16H18O5N9Cl1S3

Molecular Weight548.03

Purity98.00%

Density

Boiling Point

Melting Point

Flash Point

AppearanceWhite to off-white solid

EINECS

MSDSChineseEnglish

Symbol

Signal Word

Cat. No.: 2A-9047908 Purity: 98.00%
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Quality Control of [ 75738-58-8 ] Purity: 98.00% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number75738-58-8
Catalog No.2A-9047908
Chinese Name盐酸头孢甲肟
SynonymsApatef; SCE 1365 hydrochloride; Yamatetan; Cepan Darvilen; Apacef; Bestcall; CEFOTETAN; Cefotetan acid; Tacef; Cefmenoxime hydrochloride; Ceftenon; Abbott 50192 (HCl); CEFOTETAN SODIUM; Cefmenoxime (hydrochloride)
Molecular FormulaC16H18O5N9Cl1S3
Molecular Weight548.03
Purity98.00
AppearanceWhite to off-white solid
Storage ConditionWarehouse low temperature ventilation and drying
ApplicationCefmenoxime Hcl is a third-generation cephalosporin antibiotic.
HTC3003209000
PubChem ID7848802
MDL NumberMFCD00941441
SMILESCON=C(C(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12)c1csc(N)n1.CON=C(C(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12)c1csc(N)n1.Cl
InChIInChI=1S/2C16H17N9O5S3.ClH/c2*1-24-16(20-22-23-24)33-4-6-3-31-13-9(12(27)25(13)10(6)14(28)29)19-11(26)8(21-30-2)7-5-32-15(17)18-7;/h2*5,9,13H,3-4H2,1-2H3,(H2,17,18)(H,19,26)(H,28,29);1H/b2*21-8-;/t2*9-,13-;/m11./s1
InChI KeyMPTNDTIREFCQLK-UNVJPQNDSA-N
MSDSmsds/47908_1_75738_58_8.pdf
Use ofCefmenoxime hydrochloride is a third-generation cephalosporin antibiotic. Properties Name cefmenoxime hydrochloride Synonym More Synonyms Cefmenoxime Hydrochloride Biological Activity Description Cefmenoxime hydrochloride is a third-generation cephalosporin antibiotic. Related Catalog Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection References [1]. Yokota N, et al. Antibacterial activities of cefmenoxime against recent fresh clinical isolates from patients in sinusitis. Jpn J Antibiot. 1995 May;48(5):602-9. [2]. Paladino JA, et al. Pharmacoeconomic analysis of cefmenoxime dual individualization in the treatment of nosocomial pneumonia. Ann Pharmacother. 1994 Mar;28(3):384-9. [3]. Duncker GI, et al. Cefmenoxime in corneal organ culture. Ophthalmologica. 1994;208(5):262-6. Chemical & Physical Properties PSA 269.65000 LogP 0.04020 InChIKey MPTNDTIREFCQLK-UNVJPQNDSA-N Toxicological Information CHEMICAL IDENTIFICATION RTECS NUMBER : CAS REGISTRY NUMBER : 75738-58-8 LAST UPDATED : DATA ITEMS CITED : MOLECULAR FORMULA : MOLECULAR WEIGHT : HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : SPECIES OBSERVED : Rodent - rat DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year: 14,297,1983 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JJANAX Japanese Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo 141, Japan) V.21- 1968- Volume(issue)/page/year: 35,2615,1982 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JJANAX Japanese Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo 141, Japan) V.21- 1968- Volume(issue)/page/year: 35,2615,1982 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year: 14,297,1983 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JJANAX Japanese Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo 141, Japan) V.21- 1968- Volume(issue)/page/year: 35,2615,1982 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959- Volume(issue)/page/year: 22,1605,1980 ** OTHER MULTIPLE DOSE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : TOXIC EFFECTS : Gastrointestinal - other changes REFERENCE : TAKHAA Takeda Kenkyusho Ho. Journal of the Takeda Research Laboratories. (Takeda Yakuhin Kogyo K.K., 2-17-85 Jusohon-machi, Yodogawa-ku, Osaka 532, Japan) V.29- 1970- Volume(issue)/page/year: 42,104,1983 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : TOXIC EFFECTS : Liver - changes in liver weight Endocrine - changes in thymus weight Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase REFERENCE : YACHDS Yakuri to Chiryo. Pharmacology and Therapeutics. (Raifu Saiensu Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan) V.1- 1972- Volume(issue)/page/year: 16,2421,1988 Safety Information HS Code 3003209000
Transport InfoProduct Name: Cefmenoxime Hydrochloride
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