CAS Number74938-88-8
Synonyms(4-Carbamimidoylphenyl)methanesulfonyl fluoride hydrochloride; (4-Carbamimidoylphenyl)methanesulfonyl fluoride hydrochloride (1:1); Benzenemethanesulfonyl fluoride, 4-(aminoiminomethyl)-, hydrochloride (1:1); (4-carbamimidoylphenyl)methanesulfonyl fluoride,hydrochloride; MFCD00036898
Molecular FormulaC8H10ClFN2O2S
Molecular Weight252.69
Purity≥97 (HPLC)%
Boiling Point405.2ºC at 760 mmHg
Melting Point~205 °C (dec.)
Appearancesolid
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 74938-88-8 |
| Catalog No. | 2A-9047814 |
| Chinese Name | (4-脒苯基)甲磺酰氟盐酸盐 |
| Synonyms | (4-Carbamimidoylphenyl)methanesulfonyl fluoride hydrochloride; (4-Carbamimidoylphenyl)methanesulfonyl fluoride hydrochloride (1:1); Benzenemethanesulfonyl fluoride, 4-(aminoiminomethyl)-, hydrochloride (1:1); (4-carbamimidoylphenyl)methanesulfonyl fluoride,hydrochloride; MFCD00036898 |
| Molecular Formula | C8H10ClFN2O2S |
| Molecular Weight | 252.69 |
| Purity | ≥97 (HPLC) |
| Boiling Point | 405.2ºC at 760 mmHg |
| Melting Point | ~205 °C (dec.) |
| Appearance | solid |
| Water Solubility | H2O: 50 mM Stable when aliquoted at −20°C. Half-li |
| Storage Condition | Store in an airtight container in a cool, dry plac |
| Application | p-APMSF is an irreversible inhibitor of serinase. p-APMSF has substrate specificity for the positively charged side chains of amino acids, lysine or arginine. p-APMSF can be used to study irreversible |
| HTC | 2925290090 |
| PubChem ID | 24891118 |
| MDL Number | MFCD00078902 |
| SMILES | F[S](=O)(=O)Cc1ccc(cc1)\C(=N\[H])\N.Cl |
| InChI | 1S/C8H9FN2O2S.ClH/c9-14(12,13)5-6-1-3-7(4-2-6)8(10)11;/h1-4H,5H2,(H3,10,11);1H |
| InChI Key | KHLLRHIUKOJXLL-UHFFFAOYSA-N |
| NACRES Code | NA.77 |
| UNSPSC | 12352200 |
| Hazard Symbols | transportation |
| MSDS | msds/47814_1_74938_88_8.pdf |
| Bioactivity | p-APMSF is an irreversible inhibitor of serinase. p-APMSFhas substrate specificity for positively charged side chains of amino acids,lysine, or arginine. p-APMSF can be used to study the irreversible inhibitionof trypsin and thrombin [1]. Related Catalog Research Areas >> Others Signaling Pathways >> Others >> Others References [1]. LauraR, et al. (p-Amidinophenyl)methanesulfonyl fluoride, an irreversible inhibitorof serine proteases. Biochemistry. 1980 Oct 14;19(21):4859-64. Chemical & Physical Properties Boiling Point 405.2ºC at 760 mmHg Melting Point ~205 °C (dec.) Molecular Formula C8H10ClFN2O2S Molecular Weight 252.69 Flash Point 198.8ºC Exact Mass 252.013550 PSA 92.39000 LogP 3.45280 InChIKey KHLLRHIUKOJXLL-UHFFFAOYSA-N SMILES Cl.N=C(N)c1ccc(CS(=O)(=O)F)cc1 Storage condition −20°C Water Solubility H2O: 50 mM Stable when aliquoted at −20°C. Half-life = 6 minutes in pH 7.0 buffer systems. |
| Use of | p-APMSF is an irreversible inhibitor of serinase. p-APMSFhas substrate specificity for positively charged side chains of amino acids,lysine, or arginine. p-APMSF can be used to study the irreversible inhibitionof trypsin and thrombin [1]. Properties Name 4-Amidinophenylmethanesulfonyl fluoride hydrochloride Synonym More Synonyms Biological Activity Description p-APMSF is an irreversible inhibitor of serinase. p-APMSFhas substrate specificity for positively charged side chains of amino acids,lysine, or arginine. p-APMSF can be used to study the irreversible inhibitionof trypsin and thrombin [1]. Related Catalog Research Areas >> Others Signaling Pathways >> Others >> Others References [1]. LauraR, et al. (p-Amidinophenyl)methanesulfonyl fluoride, an irreversible inhibitorof serine proteases. Biochemistry. 1980 Oct 14;19(21):4859-64. Chemical & Physical Properties Exact Mass 252.013550 PSA 92.39000 LogP 3.45280 InChIKey KHLLRHIUKOJXLL-UHFFFAOYSA-N |
| Tax Rebate | 9.0% |
| Supervision | none |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
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