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Dynorphin A (1-13) structure, CAS 72957-38-1

Dynorphin A (1-13)

CAS Number72957-38-1

SynonymsUNII:VFC23V742Z; dynorphin A-(1-13); DYNORPHIN 1-13; DYNORPHIN A (1-13),PORCINE; dyn A-(1-13)-OH; DYNORPHIN A(HUMAN,1-13); YGGFLRRIRPKLK; Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys; Dyn(1-13); DYNORPHIN A PORCINE FRAGMENT 1-13; Dynorphin A (1-13) Acetate; Porcine dynorphin A(1-13)

Molecular FormulaC75H126N24O15

Molecular Weight1603.955

Purity98.00%

Density1.4±0.1 g/cm3

Boiling Point

Melting Point

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Cat. No.: 2A-9047521 Purity: 98.00%
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Quality Control of [ 72957-38-1 ] Purity: 98.00% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number72957-38-1
Catalog No.2A-9047521
Chinese Name强啡肽 A (1-13)
SynonymsUNII:VFC23V742Z; dynorphin A-(1-13); DYNORPHIN 1-13; DYNORPHIN A (1-13),PORCINE; dyn A-(1-13)-OH; DYNORPHIN A(HUMAN,1-13); YGGFLRRIRPKLK; Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys; Dyn(1-13); DYNORPHIN A PORCINE FRAGMENT 1-13; Dynorphin A (1-13) Acetate; Porcine dynorphin A(1-13)
Molecular FormulaC75H126N24O15
Molecular Weight1603.955
Purity98.00
Density1.4±0.1 g/cm3
Storage Condition-20°C
ApplicationPorcine dynorphin A (1-13) is a potent endogenous κ opioid receptor agonist and has analgesic effects at physiological concentrations.
PubChem ID14991637
SMILESCCC(C)C(NC(=O)C(CCCN=C(N)N)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC(C)C)NC(=O)C(Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)C(N)Cc1ccc(O)cc1)C(=O)NC(CCCN=C(N)N)C(=O)N1CCCC1C(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)NC(CCCCN)C(=O)O
InChIInChI=1S/C75H126N24O15/c1-7-45(6)61(70(111)94-53(25-17-35-87-75(83)84)71(112)99-36-18-26-58(99)69(110)93-50(21-11-13-31-76)64(105)96-56(38-44(4)5)67(108)95-54(72(113)114)22-12-14-32-77)98-65(106)52(24-16-34-86-74(81)82)91-63(104)51(23-15-33-85-73(79)80)92-66(107)55(37-43(2)3)97-68(109)57(40-46-19-9-8-10-20-46)90-60(102)42-88-59(101)41-89-62(103)49(78)39-47-27-29-48(100)30-28-47/h8-10,19-20,27-30,43-45,49-58,61,100H,7,11-18,21-26,31-42,76-78H2,1-6H3,(H,88,101)(H,89,103)(H,90,102)(H,91,104)(H,92,107)(H,93,110)(H,94,111)(H,95,108)(H,96,105)(H,97,109)(H,98,106)(H,113,114)(H4,79,80,85)(H4,81,82,86)(H4,83,84,87)/t45-,49-,50-,51-,52-,53-,54?,55-,56-,57-,58-,61-/m0/s1
InChI KeyOVVIBUHLQIYUEU-IWIISZHXSA-N
NACRES CodeNA.32
UNSPSC41116158
Hazard Symbolstransportation
MSDSmsds/47521_1_72957_38_1.pdf
BioactivityPorcine dynorphin A (1-13) is a potent, endogenous κ opioid receptor agonist and is antinociceptive at physiological concentrations. Sequence: Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Others Peptides Target Κ opioid receptor[1]. In Vivo Dynorphin A (1-13) exposure (33 μM) causes a significant loss in neuronal viability at 4 h with a visible destruction in neuronal morphology seen at 16 h. Exposure to dynorphin A (1-13) causes acute increases in [Ca2+]i in individual neurons similar to increases seen with acute NMDA treatment. Continuous exposure to dynorphin A (1-13) (100 μM) causes a significant loss of neurons over time[1]. References [1]. Hauser KF, et al. Dynorphin A (1-13) neurotoxicity in vitro: opioid and non-opioid mechanisms in mouse spinal cord neurons. Exp Neurol. 1999 Dec;160(2):361-75. Chemical & Physical Properties Density 1.4±0.1 g/cm3 Molecular Formula C75H126N24O15 Molecular Weight 1603.955 Exact Mass 1602.983398 PSA 661.70000 LogP -0.50 Index of Refraction 1.645 InChIKey OVVIBUHLQIYUEU-IWIISZHXSA-N SMILES CCC(C)C(NC(=O)C(CCCN=C(N)N)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC(C)C)NC(=O)C(Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)C(N)Cc1ccc(O)cc1)C(=O)NC(CCCN=C(N)N)C(=O)N1CCCC1C(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)NC(CCCCN)C(=O)O Storage condition -20°C
Use ofPorcine dynorphin A (1-13) is a potent, endogenous κ opioid receptor agonist and is antinociceptive at physiological concentrations. Sequence: Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys. Properties Articles29 Name Dynorphin A (1-13) Synonym More Synonyms Dynorphin A (1-13) Biological Activity Description Porcine dynorphin A (1-13) is a potent, endogenous κ opioid receptor agonist and is antinociceptive at physiological concentrations. Sequence: Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Others Κ opioid receptor[1]. In Vivo Dynorphin A (1-13) exposure (33 μM) causes a significant loss in neuronal viability at 4 h with a visible destruction in neuronal morphology seen at 16 h. Exposure to dynorphin A (1-13) causes acute increases in [Ca2+]i in individual neurons similar to increases seen with acute NMDA treatment. Continuous exposure to dynorphin A (1-13) (100 μM) causes a significant loss of neurons over time[1]. References [1]. Hauser KF, et al. Dynorphin A (1-13) neurotoxicity in vitro: opioid and non-opioid mechanisms in mouse spinal cord neurons. Exp Neurol. 1999 Dec;160(2):361-75. Chemical & Physical Properties Molecular Formula C75H126N24O15 Exact Mass 1602.983398 PSA 661.70000 LogP -0.50 Index of Refraction 1.645 InChIKey OVVIBUHLQIYUEU-IWIISZHXSA-N
Transport InfoProduct name: Purity: 98.0%
MSDS Transport InfoModule 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available
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