| Chemical & Physical Properties | |
|---|---|
| CAS Number | 72088-94-9 |
| Catalog No. | 2A-9047411 |
| Chinese Name | 5(6)-羧基荧光素 |
| Synonyms | MFCD00151081; Fluoresceincarboxylic Acid; EINECS 276-331-1 |
| Molecular Formula | C21H12O7 |
| Molecular Weight | 376.32 |
| Purity | ≥95 (HPLC) |
| Melting Point | 275 °C (dec.) (lit.) |
| Appearance | powder |
| Water Solubility | slightly soluble in water |
| Storage Condition | Store in an airtight container in a cool, dry plac |
| Application | 5(6)-Carboxyfluorescein fluorescent probe molecule. |
| EINECS | 276-331-1 |
| HTC | 29335995 |
| PubChem ID | 329752213 |
| MDL Number | MFCD00151081 |
| SMILES | OC(=O)c1ccc2c(c1)C(=O)OC23c4ccc(O)cc4Oc5cc(O)ccc35.OC(=O)c6ccc7C(=O)OC8(c9ccc(O)cc9Oc%10cc(O)ccc8%10)c7c6 |
| InChI | 1S/2C21H12O7/c22-11-2-5-15-17(8-11)27-18-9-12(23)3-6-16(18)21(15)14-4-1-10(19(24)25)7-13(14)20(26)28-21;22-11-2-5-14-17(8-11)27-18-9-12(23)3-6-15(18)21(14)16-7-10(19(24)25)1-4-13(16)20(26)28-21/h2*1-9,22-23H,(H,24,25) |
| InChI Key | BPVHBBXCESDRKW-UHFFFAOYSA-N |
| NACRES Code | NA.32 |
| UNSPSC | 12171500 |
| Hazard Symbols | transportation |
| MSDS | msds/47411_1_72088_94_9.pdf |
| Bioactivity | 5(6)-Carboxyfluorescein contains a carboxylic acid that can be used to react with primary amines via carbodiimide activation of the carboxylic acid; cell-impermeant 5,6-FAM can also be used as a nonfixable polar tracer to investigate fusion, lysis and gap-junctional communication and to detect changes in cell or liposome volume. Related Catalog Signaling Pathways >> Others >> Others Dye Reagents Research Areas >> Others References [1]. Babcock DF. Examination of the intracellular ionic environment and of ionophore action by null point measurements employing the fluorescein chromophore. J Biol Chem. 1983 May 25;258(10):6380-9. [2]. Bonizzoni M, et al. PAMAM dendrimer-induced aggregation of 5(6)-carboxyfluorescein. J Org Chem. 2012 Feb 3;77(3):1258-66. Chemical & Physical Properties Melting Point 275 °C Molecular Formula C21H12O7 Molecular Weight 376.32 PSA 226.58000 LogP 6.72800 InChIKey BPVHBBXCESDRKW-UHFFFAOYSA-N SMILES O=C(O)c1ccc2c(c1)C(=O)OC21c2ccc(O)cc2Oc2cc(O)ccc21.O=C(O)c1ccc2c(c1)C1(OC2=O)c2ccc(O)cc2Oc2cc(O)ccc21 Storage condition Store at 2-8 |
| Use of | 5(6)-Carboxyfluorescein contains a carboxylic acid that can be used to react with primary amines via carbodiimide activation of the carboxylic acid; cell-impermeant 5,6-FAM can also be used as a nonfixable polar tracer to investigate fusion, lysis and gap-junctional communication and to detect changes in cell or liposome volume. Properties Articles64 Name 5(6)-Carboxyfluorescein Synonym More Synonyms 5(6)-Carboxyfluorescein Biological Activity Description 5(6)-Carboxyfluorescein contains a carboxylic acid that can be used to react with primary amines via carbodiimide activation of the carboxylic acid; cell-impermeant 5,6-FAM can also be used as a nonfixable polar tracer to investigate fusion, lysis and gap-junctional communication and to detect changes in cell or liposome volume. Related Catalog Signaling Pathways >> Others >> Others Dye Reagents Research Areas >> Others References [1]. Babcock DF. Examination of the intracellular ionic environment and of ionophore action by null point measurements employing the fluorescein chromophore. J Biol Chem. 1983 May 25;258(10):6380-9. [2]. Bonizzoni M, et al. PAMAM dendrimer-induced aggregation of 5(6)-carboxyfluorescein. J Org Chem. 2012 Feb 3;77(3):1258-66. Chemical & Physical Properties Molecular Formula C21H12O7 PSA 226.58000 LogP 6.72800 InChIKey BPVHBBXCESDRKW-UHFFFAOYSA-N Storage condition Store at 2-8 |
| Transport Info | Product name: Purity: 95.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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