| Chemical & Physical Properties | |
|---|---|
| CAS Number | 70363-83-6 |
| Catalog No. | 2A-9047155 |
| Chinese Name | 双(1,3-二巴比妥酸)-三次甲基氧烯洛尔 |
| Synonyms | dibac4(3); MFCD00467633 |
| Molecular Formula | C27H40O6N4 |
| Molecular Weight | 516.64 |
| Purity | 98.00 |
| Storage Condition | 2~8°C |
| Application | DiBAC4(3) is a voltage-sensitive fluorescent dye (λex=490 nm, λem=505 nm). |
| MDL Number | MFCD23103932 |
| Hazard Symbols | transportation |
| MSDS | msds/47155_1_70363_83_6.pdf |
| Bioactivity | DiBAC4(3) is a voltage-sensitive fluorescent dye (λex=490 nm, λem=505 nm). Related Catalog Signaling Pathways >> Others >> Others Dye Reagents Research Areas >> Others In Vitro The membrane hyperpolarization induced by 10 μM Evans blue (EB) in HEKBKα is clearly observed with DiBAC4(3), while the change in membrane potential (MP) by addition of 3 mM tetraethylammonium chloride (TEA) appears more slowly than that measured with microelectrode. The time to peak of hyperpolarization is 2.3±0.9 s (n=4) and 35.0±2.6 s (n=12, P<0.01) by the measurements with microelectrodes and DiBAC4(3), respectively[1]. Cell Assay Prior to the fluorescence measurements, cells are incubated in KRH (Krebs-Ringer-HEPES) buffer containing with 100 nM DiBAC4(3) for 20 min at room temperature. The stained cells are used for experiments without washing. The fluorescence emission is collected using a 505 nm dicroic mirror and a BA filter (>520 nm)[1]. References [1]. Yamada A, et al. Usefulness and limitation of DiBAC4(3), a voltage-sensitive fluorescent dye, for the measurement of membrane potentials regulated by recombinant large conductance Ca2+-activated K+ channels in HEK293 cells. Jpn J Pharmacol. 2001 Jul;86(3):342-50. Chemical & Physical Properties Molecular Formula C27H40N4O6 Molecular Weight 516.63 PSA 200.30000 LogP 2.90160 Storage condition 2~8°C |
| Use of | DiBAC4(3) is a voltage-sensitive fluorescent dye (λex=490 nm, λem=505 nm). Properties Articles24 Name Bis(1,3-dibutylbarbituric acid) trimethine oxonol Synonym More Synonyms DiSBAC2(5) Biological Activity Description DiBAC4(3) is a voltage-sensitive fluorescent dye (λex=490 nm, λem=505 nm). Related Catalog Signaling Pathways >> Others >> Others Dye Reagents Research Areas >> Others References Chemical & Physical Properties Molecular Formula C27H40N4O6 PSA 200.30000 LogP 2.90160 |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
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