CAS Number69256-17-3
Synonyms1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione; 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-methyluracil; 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione
Molecular FormulaC10H13O5N2F1
Molecular Weight260.22
Purity98.00%
Density1.6±0.1 g/cm3
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 69256-17-3 |
| Catalog No. | 2A-9046990 |
| Chinese Name | 2'-氟-5-甲基阿拉伯糖基尿嘧啶 |
| Synonyms | 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione; 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-methyluracil; 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione |
| Molecular Formula | C10H13O5N2F1 |
| Molecular Weight | 260.22 |
| Purity | 98.00 |
| Density | 1.6±0.1 g/cm3 |
| Storage Condition | 2-8°C, dry and sealed |
| Application | FMAU is a thymidine analogue. This series of analogues has insertional activity on replicated DNA. They can be used to label cells and track DNA synthesis [1]. |
| HTC | 2934999090 |
| PubChem ID | 598487 |
| MDL Number | MFCD00870799 |
| SMILES | Cc1cn(C2OC(CO)C(O)C2F)c(=O)[nH]c1=O |
| InChI | InChI=1S/C10H13FN2O5/c1-4-2-13(10(17)12-8(4)16)9-6(11)7(15)5(3-14)18-9/h2,5-7,9,14-15H,3H2,1H3,(H,12,16,17)/t5-,6+,7-,9-/m1/s1 |
| InChI Key | GBBJCSTXCAQSSJ-JVZYCSMKSA-N |
| MSDS | msds/46990_1_69256_17_3.pdf |
| Use of | FMAU is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis[1]. Properties Name 1-(2-Deoxy-2-fluoro-.β.-D-arabinofuranosyl)-5-methyluracil Synonym More Synonyms 2'-Fluoro-5-methylarabinosyluracil Biological Activity Description FMAU is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis[1]. Related Catalog Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Research Areas >> Others References [1]. Cavanagh BL, et al. Thymidine analogues for tracking DNA synthesis. Molecules. 2011 Sep 15;16(9):7980-93. Chemical & Physical Properties Molecular Formula C10H13FN2O5 Exact Mass 260.080841 PSA 104.55000 LogP -0.72 Index of Refraction 1.593 InChIKey GBBJCSTXCAQSSJ-JVZYCSMKSA-N Toxicological Information CHEMICAL IDENTIFICATION RTECS NUMBER : CHEMICAL NAME : Uracil, 1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-methyl - CAS REGISTRY NUMBER : 69256-17-3 LAST UPDATED : DATA ITEMS CITED : MOLECULAR FORMULA : C10-H13-F-N2-O5 MOLECULAR WEIGHT : WISWESSER LINE NOTATION : T6NVMVJ E1 A- BT5OTJ CF DQ E1Q HEALTH HAZARD DATA ACUTE TOXICITY DATA MUTATION DATA TYPE OF TEST : DNA inhibition TEST SYSTEM : Rodent - mouse Leukocyte DOSE/DURATION : REFERENCE : Safety Information HS Code 2934999090 Synthetic Route 3',5&rsqu... 97614-47-6 2'-Fluoro-5... 69256-17-3 Literature: Wang, Qiang; Li, Yanfeng; Song, Chuanjun; Qian, Keduo; Chen, Chin-Ho; Lee, Kuo-Hsiung; Chang, Junbiao Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 14 p. 4053 - 4056 1-(3-O-Acetyl-5... 69124-04-5 2'-Fluoro-5... 69256-17-3 Literature: US4211773 A1, ; US4594339 A1, ; 2-Deoxy-2-fluor... 97614-43-2 2'-Fluoro-5... 69256-17-3 Literature: Nucleosides, nucleotides and nucleic acids, , vol. 22, # 5-8 p. 1343 - 1346 Precursor & DownStream Precursor 10 CAS#:97614-47-6 3',5'-Di-O-benz... CAS#:69124-04-5 1-(3-O-Acetyl-5... CAS#:97614-43-2 2-Deoxy-2-fluor... CAS#:97614-44-3 2-Deoxy-2-fluor... DownStream 6 CAS#:105281-19-4 1-[(2R,3S,4R,5S... CAS#:144822-48-0 1-[5-O-[Bis(4-m... CAS#:40615-39-2 5'-O-Dimethoxyt... CAS#:128114-99-8 Trityl-lyxofura... |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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