CAS Number68189-43-5
Synonyms3,3'-Piperazine-1,4-diylbis(2-hydroxypropane-1-sulfonic acid); MFCD00038350; 3,3'-(1,4-Piperazinediyl)bis(2-hydroxy-1-propanesulfonic acid); EINECS 269-199-1; 2-hydroxy-3-[4-(2-hydroxy-3-sulfopropyl)piperazin-1-yl]propane-1-sulfonic acid
Molecular FormulaC10H22N2O8S2
Molecular Weight362.42 (anhydrous basis)
Purity≥99 (titration)%
Density1.6±0.1 g/cm3
Melting Point320°C
Appearancecrystalline powder
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| Chemical & Physical Properties | |
|---|---|
| CAS Number | 68189-43-5 |
| Catalog No. | 2A-9046732 |
| Chinese Name | POPSO 水合物 |
| Synonyms | 3,3'-Piperazine-1,4-diylbis(2-hydroxypropane-1-sulfonic acid); MFCD00038350; 3,3'-(1,4-Piperazinediyl)bis(2-hydroxy-1-propanesulfonic acid); EINECS 269-199-1; 2-hydroxy-3-[4-(2-hydroxy-3-sulfopropyl)piperazin-1-yl]propane-1-sulfonic acid |
| Molecular Formula | C10H22N2O8S2 |
| Molecular Weight | 362.42 (anhydrous basis) |
| Purity | ≥99 (titration) |
| Density | 1.6±0.1 g/cm3 |
| Melting Point | 320°C |
| Appearance | crystalline powder |
| Water Solubility | 1 M NaOH: 0.1 M, clear, colorless |
| Storage Condition | Store in an airtight container in a cool, dry plac |
| Application | POPSO is a zwitterionic buffer that can increase osmotic pressure and has a significant inhibitory effect on anionic single ports. POPSO inhibits chloride single transport with an IC50 value of 24 mM. |
| HTC | 2933599090 |
| PubChem ID | 24898407 |
| SMILES | O.OC(CN1CCN(CC1)CC(O)CS(O)(=O)=O)CS(O)(=O)=O |
| InChI | 1S/C10H22N2O8S2.H2O/c13-9(7-21(15,16)17)5-11-1-2-12(4-3-11)6-10(14)8-22(18,19)20;/h9-10,13-14H,1-8H2,(H,15,16,17)(H,18,19,20);1H2 |
| InChI Key | VPTYCVRYPYNQLU-UHFFFAOYSA-N |
| Beilstein/REAXYS | 842252 |
| NACRES Code | NA.25 |
| UNSPSC | 12161700 |
| MSDS | msds/46732_1_68189_43_5.pdf |
| Bioactivity | POPSO is a zwitterionic buffer, increases osmolality and shows marked inhibition of anion uniport. POPSO inhibits chloride uniport with an IC50 value of 24 mM. POPSO enhances copper uptake and toxicity in alga, impairs mitochondrial inner membrane. The working pH range of POPSO sesquisodium salt is 7.2-8.5[1][2][3]. Related Catalog Research Areas >> Others Signaling Pathways >> Others >> Others References [1]. Ng LT, et al. Effect of buffers and osmolality on anion uniport across the mitochondrial inner membrane. Biochim Biophys Acta. 1993 Jun 10;1143(1):29-37. [2]. Vasconcelos, et al. Influence of zwitterionic pH buffers on the bioavailability and toxicity of copper to the alga Amphidinium carterae. 2009 Nov;19(10):2542-2550. [3]. Kebede N, et al. Electrogenerated chemiluminescence of tris(2,2' bipyridine)ruthenium(II) using common biological buffers as co-reactant, pH buffer and supporting electrolyte. Analyst. 2015 Nov 7;140(21):7142-5. Chemical & Physical Properties Density 1.6±0.1 g/cm3 Melting Point 320°C Molecular Formula C10H22N2O8S2 Molecular Weight 362.420 Exact Mass 362.081757 PSA 172.44000 LogP -4.05 Index of Refraction 1.593 InChIKey LVQFQZZGTZFUNF-UHFFFAOYSA-N SMILES O=S(=O)(O)CC(O)CN1CCN(CC(O)CS(=O)(=O)O)CC1 Storage condition Store at RT. Water Solubility 1 M NaOH: 0.1 M, clear, colorless |
| Use of | Properties Name Piperazine-1,4-bis(2-hydroxypropanesulfonic acid) dihydrate Synonym More Synonyms Biological Activity Related Catalog Research Areas >> Others Signaling Pathways >> Others >> Others References [1]. Ng LT, et al. Effect of buffers and osmolality on anion uniport across the mitochondrial inner membrane. Biochim Biophys Acta. 1993 Jun 10;1143(1):29-37. [2]. Vasconcelos, et al. Influence of zwitterionic pH buffers on the bioavailability and toxicity of copper to the alga Amphidinium carterae. 2009 Nov;19(10):2542-2550. [3]. Kebede N, et al. Electrogenerated chemiluminescence of tris(2,2' bipyridine)ruthenium(II) using common biological buffers as co-reactant, pH buffer and supporting electrolyte. Analyst. 2015 Nov 7;140(21):7142-5. Chemical & Physical Properties Molecular Formula C10H22N2O8S2 Exact Mass 362.081757 PSA 172.44000 LogP -4.05 Index of Refraction 1.593 InChIKey LVQFQZZGTZFUNF-UHFFFAOYSA-N Storage condition Store at RT. Water Solubility 1 M NaOH: 0.1 M, clear, colorless |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Purity: 99.0% |
| MSDS Transport Info | Module 14. Shipping information United Nations classification: inconsistent with United Nations classification standards UN number: not specified |
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