| Chemical & Physical Properties | |
|---|---|
| CAS Number | 65995-63-3 |
| Catalog No. | 2A-9046361 |
| Chinese Name | 安石榴甙； 安石榴苷 |
| Synonyms | pulchinenoside b4(rg) |
| Molecular Formula | C48H28O30 |
| Molecular Weight | 1084.72 |
| Purity | 98.00 |
| Density | 2.1±0.1 g/cm3 |
| Appearance | faint yellow to dark yellow |
| Water Solubility | methanol: soluble5mg/mL, clear |
| Storage Condition | 2-8°C |
| Application | Punicalagin is a polyphenolic component isolated from the leaves of pomegranate (Punica granatum L.) or Terminalia catappa L. Punicalagin is an anti-hepatitis B virus (HBV) drug with antioxidant, anti |
| PubChem ID | 329757633 |
| SMILES | O=C1OC2C(O)OC3COC(=O)c4cc(O)c(O)c(O)c4-c4c(O)c(O)c5oc(=O)c6c(c(O)c(O)c7oc(=O)c4c5c76)-c4c(cc(O)c(O)c4O)C(=O)OC3C2OC(=O)c2cc(O)c(O)c(O)c2-c2c1cc(O)c(O)c2O |
| InChI | InChI=1S/C48H28O30/c49-10-1-6-17(31(59)27(10)55)19-23-21-22-24(47(70)76-38(21)35(63)33(19)61)20(34(62)36(64)39(22)75-46(23)69)18-9(4-13(52)28(56)32(18)60)43(66)74-37-14(5-72-42(6)65)73-48(71)41-40(37)77-44(67)7-2-11(50)25(53)29(57)15(7)16-8(45(68)78-41)3-12(51)26(54)30(16)58/h1-4,14,37,40-41,48-64,71H,5H2 |
| InChI Key | ZJVUMAFASBFUBG-OGJBWQGYSA-N |
| Hazard Symbols | transportation |
| Bioactivity | Punicalagin is a polyphenol ingredient isolated from Pomegranate (Punica granatum L.) or the leaves of Terminalia catappa L.. Punicalagin is a anti-hepatitis B virus (HBV) agent and has antioxidant, anti-inflammatory, and anticancer effects[1][2][3]. Related Catalog Research Areas >> Cancer Research Areas >> Infection Signaling Pathways >> Anti-infection >> HBV Research Areas >> Metabolic Disease In Vitro Punicalagin (100 mg/ml) induces apoptosis in HT-29, HCT116 colon cells[1]. In Vivo Punicalagin (10 mg/kg) inhibits the edema rate of 58.15% in rats[2]. References [1]. Seeram NP, et al. In vitro antiproliferative, apoptotic and antioxidant activities of punicalagin, ellagicacid and a total pomegranate tannin extract are enhanced in combination with otherpolyphenols as found in pomegranate juice. J Nutr Biochem. 2005 Jun;16(6):360-7. [2]. Lin CC, et al. Effects of punicalagin and punicalin on carrageenan-induced inflammation in rats. Am J Chin Med. 1999;27(3-4):371-6. [3]. Liu C, et al. Identification of hydrolyzable tannins (punicalagin, punicalin and geraniin) as novel inhibitors of hepatitis B virus covalently closed circular DNA. Antiviral Res. 2016 Oct;134:97-107. Chemical & Physical Properties Density 2.1±0.1 g/cm3 Molecular Formula C48H28O30 Molecular Weight 1084.718 Exact Mass 1084.066528 PSA 518.76000 LogP 2.36 Appearance of Characters faint yellow to dark yellow Index of Refraction 1.893 InChIKey ZJVUMAFASBFUBG-OGJBWQGYSA-N SMILES O=C1OC2C(O)OC3COC(=O)c4cc(O)c(O)c(O)c4-c4c(O)c(O)c5oc(=O)c6c(c(O)c(O)c7oc(=O)c4c5c76)-c4c(cc(O)c(O)c4O)C(=O)OC3C2OC(=O)c2cc(O)c(O)c(O)c2-c2c1cc(O)c(O)c2O Storage condition 2-8°C Water Solubility methanol: soluble5mg/mL, clear |
| Use of | Punicalagin is a polyphenol ingredient isolated from Pomegranate (Punica granatum L.) or the leaves of Terminalia catappa L.. Punicalagin is a anti-hepatitis B virus (HBV) agent and has antioxidant, anti-inflammatory, and anticancer effects[1][2][3]. Properties Articles30 Name Punicalagin Synonym More Synonyms Punicalagin Biological Activity Description Punicalagin is a polyphenol ingredient isolated from Pomegranate (Punica granatum L.) or the leaves of Terminalia catappa L.. Punicalagin is a anti-hepatitis B virus (HBV) agent and has antioxidant, anti-inflammatory, and anticancer effects[1][2][3]. Related Catalog Research Areas >> Cancer Research Areas >> Infection Signaling Pathways >> Anti-infection >> HBV Research Areas >> Metabolic Disease References [1]. Seeram NP, et al. In vitro antiproliferative, apoptotic and antioxidant activities of punicalagin, ellagicacid and a total pomegranate tannin extract are enhanced in combination with otherpolyphenols as found in pomegranate juice. J Nutr Biochem. 2005 Jun;16(6):360-7. [2]. Lin CC, et al. Effects of punicalagin and punicalin on carrageenan-induced inflammation in rats. Am J Chin Med. 1999;27(3-4):371-6. [3]. Liu C, et al. Identification of hydrolyzable tannins (punicalagin, punicalin and geraniin) as novel inhibitors of hepatitis B virus covalently closed circular DNA. Antiviral Res. 2016 Oct;134:97-107. Chemical & Physical Properties Molecular Formula C48H28O30 Exact Mass 1084.066528 PSA 518.76000 Appearance of Characters faint yellow to dark yellow Index of Refraction 1.893 InChIKey ZJVUMAFASBFUBG-OGJBWQGYSA-N |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
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