CAS Number65195-55-3
Synonyms5-O-Demethyl Antibiotic C 076A1a; Abamectinum [Latin]; Abamectin B1a; AVERMECTIN B1A; Abamectine [French]; [3H]-Abamectin B1a; Abamectin komponente B1a; 22,23-dihydroavermectinh B1a; abamectin component B1a; Avermectin B(1)a; Abamectina [Spanish]; Vertimec(R)018SC; Caswell No. 063AB; Antibiotic C 076B1a
Molecular FormulaC48H72O14
Molecular Weight873.077
Purity98.00%
Density1.2±0.1 g/cm3
Boiling Point940.9±65.0 °C at 760 mmHg
Melting Point157-162ºC
AppearanceWhite crystalline powder
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 65195-55-3 |
| Catalog No. | 2A-0202358 |
| Chinese Name | 阿维菌素 |
| Synonyms | 5-O-Demethyl Antibiotic C 076A1a; Abamectinum [Latin]; Abamectin B1a; AVERMECTIN B1A; Abamectine [French]; [3H]-Abamectin B1a; Abamectin komponente B1a; 22,23-dihydroavermectinh B1a; abamectin component B1a; Avermectin B(1)a; Abamectina [Spanish]; Vertimec(R)018SC; Caswell No. 063AB; Antibiotic C 076B1a |
| Molecular Formula | C48H72O14 |
| Molecular Weight | 873.077 |
| Purity | 98.00 |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 940.9±65.0 °C at 760 mmHg |
| Melting Point | 157-162ºC |
| Appearance | White crystalline powder |
| Storage Condition | Ventilated and low temperature drying |
| Packaging | II |
| Application | Avermectin B1a is an antiparasitic agent that paralyzes nematodes. |
| HTC | 2932999099 |
| SMILES | CCC(C)C1OC2(C=CC1C)CC1CC(CC=C(C)C(OC3CC(OC)C(OC4CC(OC)C(O)C(C)O4)C(C)O3)C(C)C=CC=C3COC4C(O)C(C)=CC(C(=O)O1)C34O)O2 |
| InChI | InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12+,27-15+,32-14+/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1 |
| InChI Key | RRZXIRBKKLTSOM-XPNPUAGNSA-N |
| Hazard Symbols | 6.1(a) |
| MSDS | msds/46220_1_65195_55_3.pdf |
| Use of | Avermectin B1a is an antiparasitic agent that paralyzes nematodes without causing hypercontraction or flaccid paralysis. Properties Name avermectin B1a Synonym More Synonyms Avermectin B1a Biological Activity Description Avermectin B1a is an antiparasitic agent that paralyzes nematodes without causing hypercontraction or flaccid paralysis. Related Catalog Signaling Pathways >> Anti-infection >> Parasite Research Areas >> Infection References [1]. Sun Y, et al. [Effects of avermectin B1a on soil microorganism and earthworm (Eisenia fetida)]. Ying Yong Sheng Tai Xue Bao. 2005 Nov;16(11):2140-3. [2]. Sun Y, et al. Bioaccumulation and elimination of avermectin B1a in the earthworms (Eisenia fetida). Chemosphere. 2005 Jul;60(5):699-704. [3]. Huang J, et al. Avermectin B1a binds to high- and low-affinity sites with dual effects on the gamma-aminobutyric acid-gated chloride channel of cultured cerebellar granule neurons. J Pharmacol Exp Ther. 1997 Apr;281(1):261-6. [4]. Payne GT, et al. Activation of gamma-aminobutyric acid insensitive chloride channels in mouse brain synaptic vesicles by avermectin B1a. J Biochem Toxicol. 1991 Winter;6(4):283-92. Chemical & Physical Properties Molecular Formula C48H72O14 Exact Mass 872.492188 PSA 170.06000 Index of Refraction 1.571 InChIKey RRZXIRBKKLTSOM-XPNPUAGNSA-N Toxicological Information CHEMICAL IDENTIFICATION RTECS NUMBER : CHEMICAL NAME : Avermectin A1a, 5-O-demethyl- CAS REGISTRY NUMBER : 65195-55-3 LAST UPDATED : DATA ITEMS CITED : MOLECULAR FORMULA : C48-H72-O14 MOLECULAR WEIGHT : HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD20 - Lethal Dose ROUTE OF EXPOSURE : SPECIES OBSERVED : Rodent - rat DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JAFCAU Journal of Agricultural and Food Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) V.1- 1953- Volume(issue)/page/year: 32,94,1984 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rat DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JAFCAU Journal of Agricultural and Food Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) V.1- 1953- Volume(issue)/page/year: 32,94,1984 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JAFCAU Journal of Agricultural and Food Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) V.1- 1953- Volume(issue)/page/year: 42,1786,1994 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JAFCAU Journal of Agricultural and Food Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) V.1- 1953- Volume(issue)/page/year: 32,94,1984 Safety Information RIDADR UN 2588 Packaging Group II Hazard Class 6.1(a) HS Code 2932999099 Synthetic Route 4'',5-d... 81924-42-7 Avermectin B1a 65195-55-3 Literature: Katoh, Tadashi; Itoh, Etsuko; Terashima, Shiro Heterocycles, 2000 , vol. 52, # 2 p. 587 - 590 106544-70-1 Avermectin B1a 65195-55-3 Literature: Hanessian; Ugolini; Dube; et al. Journal of the American Chemical Society, 1986 , vol. 108, # 10 p. 2776 - 2778 Avermectin B1a 65195-55-3 Avermectin B1a 65195-55-3 Δ2-4(R)-a... 110415-68-4 Literature: Journal of the American Chemical Society, , vol. 109, # 23 p. 7063 - 7067 Precursor & DownStream Precursor 9 CAS#:81924-42-7 4'',5-di-O-tert... CAS#:106544-70-1 CAS#:65195-55-3 Avermectin B1a CAS#:71826-88-5 DownStream 2 CAS#:65195-55-3 Avermectin B1a CAS#:110415-68-4 Δ2-4(R)-avermec... |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
| Related Products in Specialty Chemicals | ||
|---|---|---|
| 1-Methoxy-5-methylphenazinium methyl sulfate | 65162-13-2 | 2A-9046213 |
| N-Methyl-2,2'-iminodi(8-quinolinol) | 65165-14-2 | 2A-9046214 |
| Bis[2-(2-chloroethylsulfonyl)ethyl]azanium chloride | 65180-91-8 | 2A-9046216 |
| N,N'-Bis(3-methylphenyl)-N,N'-bis(phenyl)benzidine | 65181-78-4 | 2A-9046218 |
| 2-Bromophenethylamine | 65185-58-2 | 2A-9046219 |
| Avermectin B1b | 65195-56-4 | 2A-9046221 |
| Guayule | 65202-07-5 | 2A-9046223 |
| 4-((2-Hydroxyethyl)amino)-3-nitrophenol | 65235-31-6 | 2A-9046228 |
| Cefetamet pivoxyl | 65243-33-6 | 2A-9046229 |
| 2-(3-tert-Butyl-4-hydroxyphenoxy)-N-(4-chloro-3-((4-((3,4-dimethoxyphenyl)azo)-4,5-dihydro-5-oxo-1-(2,4,6-trichlorophenyl)-1H-pyrazol-3-yl)amino)phenyl)myristamide | 65293-90-5 | 2A-9046235 |
| Browse all Specialty Chemicals products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA
EN
SDS