CAS Number63644-62-2
Synonyms(2E)-3-(4-Hydroxy-3-methoxyphenyl)-2-propen-1-yl (2E)-3-(4-hydroxy-3-methoxyphenyl)acrylate; [(E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enyl] (E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate; 2-Propenoic acid, 3-(4-hydroxy-3-methoxyphenyl)-, 3-(4-hydroxy-3-methoxyphenyl)-2-propenyl ester
Molecular FormulaC20H20O6
Molecular Weight356.38
Purity98.00%
Density1.3±0.1 g/cm3
Boiling Point570.5±50.0 °C at 760 mmHg
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 63644-62-2 |
| Catalog No. | 2A-9045942 |
| Chinese Name | 阿魏酸松柏酯 |
| Synonyms | (2E)-3-(4-Hydroxy-3-methoxyphenyl)-2-propen-1-yl (2E)-3-(4-hydroxy-3-methoxyphenyl)acrylate; [(E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enyl] (E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate; 2-Propenoic acid, 3-(4-hydroxy-3-methoxyphenyl)-, 3-(4-hydroxy-3-methoxyphenyl)-2-propenyl ester |
| Molecular Formula | C20H20O6 |
| Molecular Weight | 356.38 |
| Purity | 98.00 |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 570.5±50.0 °C at 760 mmHg |
| Storage Condition | 2-8C |
| Application | Coniferyl ferulate, a potent inhibitor of glutathione S-transferase (GST) isolated from Angelicae sinensis, reverses multidrug resistance and downregulates P-glycoprotein. Coniferyl ferulate strongly |
| HTC | 2918990090 |
| PubChem ID | 24636836 |
| MDL Number | MFCD13195559 |
| SMILES | COc1cc(C=CCOC(=O)C=Cc2ccc(O)c(OC)c2)ccc1O |
| InChI | InChI=1S/C20H20O6/c1-24-18-12-14(5-8-16(18)21)4-3-11-26-20(23)10-7-15-6-9-17(22)19(13-15)25-2/h3-10,12-13,21-22H,11H2,1-2H3/b4-3+,10-7+ |
| InChI Key | PGLIMMMHQDNVRS-YZQQHVNFSA-N |
| MSDS | msds/45942_1_63644_62_2.pdf |
| Use of | Coniferyl ferulate, a strong inhibitor of glutathione S-transferase (GST) isolated from Radix Angelicae sinensis, reverses multidrug resistance and downregulates P-glycoprotein. Coniferyl ferulate shows strong inhibition of human placental GST with an IC50 of 0.3 μM[1]. Properties Name 3-(4-Hydroxy-3-methoxyphenyl)allyl 3-(4-hydroxy-3-methoxyphenyl)acrylate Synonym More Synonyms Coniferyl ferulate Biological Activity Description Coniferyl ferulate, a strong inhibitor of glutathione S-transferase (GST) isolated from Radix Angelicae sinensis, reverses multidrug resistance and downregulates P-glycoprotein. Coniferyl ferulate shows strong inhibition of human placental GST with an IC50 of 0.3 μM[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Gutathione S-transferase Signaling Pathways >> Membrane Transporter/Ion Channel >> P-glycoprotein Glutathione S-transferase[1] P-glycoprotein[1] References [1]. Chen C, et al. Coniferyl Ferulate, a Strong Inhibitor of Glutathione S-Transferase Isolated from Radix Angelicae sinensis, Reverses Multidrug Resistance and Downregulates P-Glycoprotein. Evid Based Complement Alternat Med. 2013;2013:639083. Chemical & Physical Properties Molecular Formula C20H20O6 Exact Mass 356.125977 PSA 85.22000 Index of Refraction 1.640 InChIKey PGLIMMMHQDNVRS-YZQQHVNFSA-N Safety Information HS Code 2918990090 Synthetic Route Total: 1 Page trans-4-Acetoxy... CAS#:34749-55-8 Coniferyl ferulate CAS#:63644-62-2 Literature: RSC Advances, , vol. 3, # 44 p. 21964 - 21971 4-Oacetylferuli... CAS#:55882-65-0 4-O-acetyl-coni... CAS#:81766-26-9 Coniferyl ferulate CAS#:63644-62-2 Literature: RSC Advances, , vol. 3, # 44 p. 21964 - 21971 Precursor & DownStream Precursor 2 CAS#:55882-65-0 4-Oacetylferuli... CAS#:81766-26-9 4-O-acetyl-coni... DownStream 3 CAS#:1135-24-6 ferulic acid CAS#:458-35-5 Coniferyl alcohol CAS#:63644-71-3 Gamma-Methoxyis... |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 30.0% |
| Transport Info | Product name: Summary 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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