
CAS Number62758-13-8
Synonyms3H-Phenoxazin-3-one, 7-hydroxy-, 10-oxide, sodium salt (1:1); ResazurinGr; EINECS 263-718-5; 7-sodiooxy-3H-phenoxazin-3-one 10-oxide; DIAZORESORCINOL; RESAZURIN SODIUM; 7-hydroxy-3H-phenoxazin-3-one 10-oxide sodium salt; Sodium 3-oxo-3H-phenoxazin-7-olate 10-oxide; Resazurine; RESAZOIN; REZAZURIN; RESAZURIN NA-SALT; SODIUM RESAZURIN; REISHIMUSHROOM.P.E; 7-Hydroxy-10-oxy-phenoxazin-3-on,Natrium-Verbindung; MFCD00005036
Molecular FormulaC12H6NNaO4
Molecular Weight251.17
Purity98.00%
Boiling Point477.2ºC at 760 mmHg
Melting Point>200ºC
AppearanceDark red crystals with a green sheen
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 62758-13-8 |
| Catalog No. | 2A-9045768 |
| Chinese Name | 刃天青 |
| Synonyms | 3H-Phenoxazin-3-one, 7-hydroxy-, 10-oxide, sodium salt (1:1); ResazurinGr; EINECS 263-718-5; 7-sodiooxy-3H-phenoxazin-3-one 10-oxide; DIAZORESORCINOL; RESAZURIN SODIUM; 7-hydroxy-3H-phenoxazin-3-one 10-oxide sodium salt; Sodium 3-oxo-3H-phenoxazin-7-olate 10-oxide; Resazurine; RESAZOIN; REZAZURIN; RESAZURIN NA-SALT; SODIUM RESAZURIN; REISHIMUSHROOM.P.E; 7-Hydroxy-10-oxy-phenoxazin-3-on,Natrium-Verbindung; MFCD00005036 |
| Molecular Formula | C12H6NNaO4 |
| Molecular Weight | 251.17 |
| Purity | 98.00 |
| Boiling Point | 477.2ºC at 760 mmHg |
| Melting Point | >200ºC |
| Appearance | Dark red crystals with a green sheen |
| Water Solubility | soluble |
| Storage Condition | Store in an airtight container in a cool, dry plac |
| Application | Resazurin sodium salt is frequently used to measure bacterial and eukaryotic cell viability by being reduced to the fluorescent product resorufin. |
| HTC | 2934999090 |
| PubChem ID | 24851905 |
| SMILES | O=c1ccc2[n+]([O-])c3ccc([O-])cc3oc-2c1.[Na+] |
| InChI | InChI=1S/C12H7NO4.Na/c14-7-1-3-9-11(5-7)17-12-6-8(15)2-4-10(12)13(9)16;/h1-6H,(H-,14,15,16);/q;+1/p-1 |
| InChI Key | IVGPGQSSDLDOLH-UHFFFAOYSA-M |
| Bioactivity | Resazurin sodium salt is commonly used to measure bacterial and eukaryotic cell viability through its reduction to the fluorescent product resorufin. Related Catalog Signaling Pathways >> Others >> Others Biochemical Assay Reagents Research Areas >> Others In Vitro Resazurin sodium salt is commonly used to measure bacterial and eukaryotic cell viability through its reduction to the fluorescent product resorufin. No viable bacteria are detected 24 h post-inoculation following inclusion of Resazurin sodium salt in TSBc cultures of F. tularensis LVS at the concentration of 44 μM. Lowering the Resazurin sodium salt concentration to as little as 4.4 μM still results in a 10-fold reduction in viable F. tularensis LVS compare to growth medium alone. Both Resazurin sodium salt treatments result in a significant decrease in viable F. tularensis LVS bacteria over 22 h. Treatment with Resazurin sodium salt significantly reduces the number of viable F. tularensis LVS bacteria in HEK293 cells 22 h post-infection[1]. Cell Assay F. tularensis is cultured in TSBc supplemented with 44 μM Resazurin sodium salt at 37°C with shaking for 24 h. At select time points, a Spectronic 200 Spectrophotometer is used to measure the absorbance at 600 nm and 570 nm to detect the presence of Resazurin sodium salt and resorufin, respectively. The ratio of these two optical densities is used to evaluate reduction of Resazurin sodium salt to resorufin over time[1]. References [1]. Schmitt DM, et al. The use of resazurin as a novel antimicrobial agent against Francisella tularensis. Front Cell Infect Microbiol. 2013 Dec 6;3:93. Chemical & Physical Properties Boiling Point 477.2ºC at 760 mmHg Melting Point >200ºC Molecular Formula C12H6NNaO4 Molecular Weight 251.170 Flash Point 242.4ºC Exact Mass 251.019455 PSA 78.73000 LogP 2.47010 InChIKey IVGPGQSSDLDOLH-UHFFFAOYSA-M SMILES O=c1ccc2[n+]([O-])c3ccc([O-])cc3oc-2c1.[Na+] Storage condition Store at RT. Stability Stable. Incompatible with strong oxidizing agents. Water Solubility soluble |
| Use of | Resazurin sodium salt is commonly used to measure bacterial and eukaryotic cell viability through its reduction to the fluorescent product resorufin. Properties Articles33 Name Resazurin sodium salt Synonym More Synonyms Resazurin sodium salt Biological Activity Description Resazurin sodium salt is commonly used to measure bacterial and eukaryotic cell viability through its reduction to the fluorescent product resorufin. Related Catalog Signaling Pathways >> Others >> Others Biochemical Assay Reagents Research Areas >> Others References [1]. Schmitt DM, et al. The use of resazurin as a novel antimicrobial agent against Francisella tularensis. Front Cell Infect Microbiol. 2013 Dec 6;3:93. Chemical & Physical Properties Molecular Formula C12H6NNaO4 Exact Mass 251.019455 PSA 78.73000 LogP 2.47010 InChIKey IVGPGQSSDLDOLH-UHFFFAOYSA-M Storage condition Store at RT. Stability Stable. Incompatible with strong oxidizing agents. Water Solubility soluble |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Purity: 90.0% |
| MSDS Transport Info | Module 14. Shipping information United Nations classification: inconsistent with United Nations classification standards Resazurin sodium salt Modification number: 5 Module 14. Shipping information UN number: not specified |
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