CAS Number830-96-6
Synonyms3-Indolepropionic acid; MFCD00005660; 1H-Indole-3-propanoic acid; 3-(1H-Indol-3-yl)propanoic acid; b-(3-Indolyl)propionic acid; Indole-3-propionic acid; EINECS 212-600-1; 3-(1H-Indol-3-yl)propionic acid; IPA
Molecular FormulaC11H11NO2
Molecular Weight189.21
Purity≥99.0 (T)%
Density1.3±0.1 g/cm3
Boiling Point417.6±20.0 °C at 760 mmHg
Melting Point~133 °C
Appearancesolid
EINECS212-600-1
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 830-96-6 |
| Catalog No. | 2A-9004574 |
| Chinese Name | 3-吲哚丙酸(IPA) |
| Synonyms | 3-Indolepropionic acid; MFCD00005660; 1H-Indole-3-propanoic acid; 3-(1H-Indol-3-yl)propanoic acid; b-(3-Indolyl)propionic acid; Indole-3-propionic acid; EINECS 212-600-1; 3-(1H-Indol-3-yl)propionic acid; IPA |
| Molecular Formula | C11H11NO2 |
| Molecular Weight | 189.21 |
| Purity | ≥99.0 (T) |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 417.6±20.0 °C at 760 mmHg |
| Melting Point | ~133 °C |
| Appearance | solid |
| Water Solubility | slightly soluble |
| Storage Condition | Keep container sealed and stored in a cool, dry pl |
| Application | 3-Indolepropionic acid is a powerful antioxidant with the potential to treat Alzheimer's disease. |
| EINECS | 212-600-1 |
| HTC | 29339990 |
| PubChem ID | 57651622 |
| MDL Number | MFCD00005660 |
| SMILES | OC(=O)CCc1c[nH]c2ccccc12 |
| InChI | 1S/C11H11NO2/c13-11(14)6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6H2,(H,13,14) |
| InChI Key | GOLXRNDWAUTYKT-UHFFFAOYSA-N |
| Beilstein/REAXYS | 147733 |
| NACRES Code | NA.77 |
| UNSPSC | 12352106 |
| Hazard Symbols | Transport |
| MSDS | msds/4574_1_830_96_6.pdf |
| Bioactivity | 3-Indolepropionic acid is shown to be a powerful antioxidant and has potential in the treatment for Alzheimer's disease. Related Catalog Natural Products >> Saccharides and Glycosides Research Areas >> Metabolic Disease Research Areas >> Neurological Disease Target Human Endogenous Metabolite In Vitro 3-Indolepropionic acid is shown to be a powerful antioxidant and has potential in the treatment for Alzheimer's disease[1]. 3-Indolepropionic acid is a more potent scavenger of hydroxyl radicals than melatonin. Similar to melatonin but unlike other antioxidants, 3-Indolepropionic acid scavenges radicals without subsequently generating reactive and pro-oxidant intermediate compounds[2]. It is also suggested that indolepropionic acid, a gut microbiota-produced metabolite, is a potential biomarker for the development of type 2 diabetes (T2D) that may mediate its protective effect by preservation of β-cell function[3]. References [1]. Wikoff WR, et al. Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites. Proc Natl Acad Sci U S A. 2009 Mar 10;106(10):3698-703. [2]. Reiter RJ, et al. Reactive oxygen intermediates, molecular damage, and aging. Relation to melatonin. Ann N Y Acad Sci. 1998 Nov 20;854:410-24. [3]. de Mello VDet al. Indolepropionic acid and novel lipid metabolites are associated with a lower risk of type 2 diabetes in the Finnish Diabetes Prevention Study. Sci Rep. 2017 Apr 11;7:46337. doi: 10.1038/srep46337. Chemical & Physical Properties Density 1.3±0.1 g/cm3 Boiling Point 417.6±20.0 °C at 760 mmHg Melting Point 134-135 °C(lit.) Molecular Formula C11H11NO2 Molecular Weight 189.210 Flash Point 206.4±21.8 °C Exact Mass 189.078979 PSA 53.09000 LogP 1.76 Vapour density 2.1 (vs air) Vapour Pressure 0.0±1.0 mmHg at 25°C Index of Refraction 1.667 InChIKey GOLXRNDWAUTYKT-UHFFFAOYSA-N SMILES O=C(O)CCc1c[nH]c2ccccc12 Storage condition −20°C Water Solubility slightly soluble |
| Use of | 3-Indolepropionic acid is shown to be a powerful antioxidant and has potential in the treatment for Alzheimer's disease. Properties Articles48 Name 3-(1H-indol-3-yl)propanoic acid Synonym More Synonyms 3-Indolepropionic acid Biological Activity Description 3-Indolepropionic acid is shown to be a powerful antioxidant and has potential in the treatment for Alzheimer's disease. Related Catalog Natural Products >> Saccharides and Glycosides Research Areas >> Metabolic Disease Research Areas >> Neurological Disease Human Endogenous Metabolite In Vitro 3-Indolepropionic acid is shown to be a powerful antioxidant and has potential in the treatment for Alzheimer's disease[1]. 3-Indolepropionic acid is a more potent scavenger of hydroxyl radicals than melatonin. Similar to melatonin but unlike other antioxidants, 3-Indolepropionic acid scavenges radicals without subsequently generating reactive and pro-oxidant intermediate compounds[2]. It is also suggested that indolepropionic acid, a gut microbiota-produced metabolite, is a potential biomarker for the development of type 2 diabetes (T2D) that may mediate its protective effect by preservation of β-cell function[3]. References [1]. Wikoff WR, et al. Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites. Proc Natl Acad Sci U S A. 2009 Mar 10;106(10):3698-703. [2]. Reiter RJ, et al. Reactive oxygen intermediates, molecular damage, and aging. Relation to melatonin. Ann N Y Acad Sci. 1998 Nov 20;854:410-24. Chemical & Physical Properties Molecular Formula C11H11NO2 Exact Mass 189.078979 PSA 53.09000 Vapour density 2.1 (vs air) Index of Refraction 1.667 InChIKey GOLXRNDWAUTYKT-UHFFFAOYSA-N Water Solubility slightly soluble |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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